Outcomes of varicose vein surgery in patients with HIV/AIDS – a nested case-control study

Detalhes bibliográficos
Autor(a) principal: Pereira-Neves, António
Data de Publicação: 2023
Outros Autores: Domingues-Monteiro, Diogo, Nóbrega, Leandro, Duarte-Gamas, Luís, Cerqueira, Alfredo, Rocha-Neves, João, Oliveira-Pinto, José, Mansilha, Armando
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://doi.org/10.48750/acv.492
Resumo: INTRODUCTION: Currently, people living with HIV/ AIDS (PLWHA) attain a life expectancy similar to a non-HIV population. However, these patients experience a status of chronic inflammation, which is a known cause of arteriopathy. Yet, literature is scarce regarding the potential venous inflammatory effect, especially after varicose vein surgery. The aim of this study was to perform a descriptive analysis alongside evaluating short and long- term outcomes after varicose vein surgery in PLWHA while comparing with a control group. METHODS: A retrospective nested case-control study was performed resorting to codification. All PLWHA patients which had any hospital interaction with the Vascular Surgery Department (either outpatient clinic, emergency or surgery) due to venous disease between April 2006 and December 2019 were identified. PLWHA found to have undergone varicose vein surgery within the study inclusion period were included. The immediately consecutive varicose vein surgery in a patient with no-HIV infection was included in the control group in a 1:1 ratio. Comorbidities were collected at the time of index event. RESULTS: The cohort included 118 patients (59 PLWHA and 59 control) and had a mean follow-up of 86 [Interquartile range (IQR) 25-75%, 43-111] months. At baseline, PLWHA were younger (45.2 ± 10.71 vs 49.9 ± 10.69 years, p=0.017) and had a male predominance (54% vs 27%, p=0.003). Furthermore, there were a higher prevalence of smokers (54% vs 17%, p<0.001) and history of drug abuse (34% vs 2%, p<0.001) in the study group. Although not statistically significant, PLWHA presented higher pre-operative CEAP classifications. Regarding post-operative outcomes, no differences were found for complications, reinterventions or overall-mortality. CONCLUSION: To the authors knowledge, this is the first study addressing varicose vein treatment in PLWHA. In summary, PLWHA undergoing varicose vein surgery seem to be younger and have higher CEAP classifications. Nonetheless, short and long-term outcomes seem to be good and similar to a control population. Further studies with larger populations and disease specific outcomes are necessary to confirm such findings.
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spelling Outcomes of varicose vein surgery in patients with HIV/AIDS – a nested case-control studyHIV/AIDS carechronic venous diseasevaricose veinsvenous surgeryINTRODUCTION: Currently, people living with HIV/ AIDS (PLWHA) attain a life expectancy similar to a non-HIV population. However, these patients experience a status of chronic inflammation, which is a known cause of arteriopathy. Yet, literature is scarce regarding the potential venous inflammatory effect, especially after varicose vein surgery. The aim of this study was to perform a descriptive analysis alongside evaluating short and long- term outcomes after varicose vein surgery in PLWHA while comparing with a control group. METHODS: A retrospective nested case-control study was performed resorting to codification. All PLWHA patients which had any hospital interaction with the Vascular Surgery Department (either outpatient clinic, emergency or surgery) due to venous disease between April 2006 and December 2019 were identified. PLWHA found to have undergone varicose vein surgery within the study inclusion period were included. The immediately consecutive varicose vein surgery in a patient with no-HIV infection was included in the control group in a 1:1 ratio. Comorbidities were collected at the time of index event. RESULTS: The cohort included 118 patients (59 PLWHA and 59 control) and had a mean follow-up of 86 [Interquartile range (IQR) 25-75%, 43-111] months. At baseline, PLWHA were younger (45.2 ± 10.71 vs 49.9 ± 10.69 years, p=0.017) and had a male predominance (54% vs 27%, p=0.003). Furthermore, there were a higher prevalence of smokers (54% vs 17%, p<0.001) and history of drug abuse (34% vs 2%, p<0.001) in the study group. Although not statistically significant, PLWHA presented higher pre-operative CEAP classifications. Regarding post-operative outcomes, no differences were found for complications, reinterventions or overall-mortality. CONCLUSION: To the authors knowledge, this is the first study addressing varicose vein treatment in PLWHA. In summary, PLWHA undergoing varicose vein surgery seem to be younger and have higher CEAP classifications. Nonetheless, short and long-term outcomes seem to be good and similar to a control population. Further studies with larger populations and disease specific outcomes are necessary to confirm such findings.Sociedade Portuguesa de Angiologia e Cirurgia Vascular2023-03-23info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://doi.org/10.48750/acv.492https://doi.org/10.48750/acv.492Angiologia e Cirurgia Vascular; Vol. 18 No. 4 (2022): December; 215-218Angiologia e Cirurgia Vascular; Vol. 18 N.º 4 (2022): December; 215-2182183-00961646-706Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPenghttp://acvjournal.com/index.php/acv/article/view/492http://acvjournal.com/index.php/acv/article/view/492/313Copyright (c) 2023 Angiologia e Cirurgia Vascularinfo:eu-repo/semantics/openAccessPereira-Neves, AntónioDomingues-Monteiro, DiogoNóbrega, LeandroDuarte-Gamas, LuísCerqueira, AlfredoRocha-Neves, JoãoOliveira-Pinto, JoséMansilha, Armando2023-03-24T10:30:13Zoai:ojs.acvjournal.com:article/492Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T17:46:06.126810Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Outcomes of varicose vein surgery in patients with HIV/AIDS – a nested case-control study
title Outcomes of varicose vein surgery in patients with HIV/AIDS – a nested case-control study
spellingShingle Outcomes of varicose vein surgery in patients with HIV/AIDS – a nested case-control study
Pereira-Neves, António
HIV/AIDS care
chronic venous disease
varicose veins
venous surgery
title_short Outcomes of varicose vein surgery in patients with HIV/AIDS – a nested case-control study
title_full Outcomes of varicose vein surgery in patients with HIV/AIDS – a nested case-control study
title_fullStr Outcomes of varicose vein surgery in patients with HIV/AIDS – a nested case-control study
title_full_unstemmed Outcomes of varicose vein surgery in patients with HIV/AIDS – a nested case-control study
title_sort Outcomes of varicose vein surgery in patients with HIV/AIDS – a nested case-control study
author Pereira-Neves, António
author_facet Pereira-Neves, António
Domingues-Monteiro, Diogo
Nóbrega, Leandro
Duarte-Gamas, Luís
Cerqueira, Alfredo
Rocha-Neves, João
Oliveira-Pinto, José
Mansilha, Armando
author_role author
author2 Domingues-Monteiro, Diogo
Nóbrega, Leandro
Duarte-Gamas, Luís
Cerqueira, Alfredo
Rocha-Neves, João
Oliveira-Pinto, José
Mansilha, Armando
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Pereira-Neves, António
Domingues-Monteiro, Diogo
Nóbrega, Leandro
Duarte-Gamas, Luís
Cerqueira, Alfredo
Rocha-Neves, João
Oliveira-Pinto, José
Mansilha, Armando
dc.subject.por.fl_str_mv HIV/AIDS care
chronic venous disease
varicose veins
venous surgery
topic HIV/AIDS care
chronic venous disease
varicose veins
venous surgery
description INTRODUCTION: Currently, people living with HIV/ AIDS (PLWHA) attain a life expectancy similar to a non-HIV population. However, these patients experience a status of chronic inflammation, which is a known cause of arteriopathy. Yet, literature is scarce regarding the potential venous inflammatory effect, especially after varicose vein surgery. The aim of this study was to perform a descriptive analysis alongside evaluating short and long- term outcomes after varicose vein surgery in PLWHA while comparing with a control group. METHODS: A retrospective nested case-control study was performed resorting to codification. All PLWHA patients which had any hospital interaction with the Vascular Surgery Department (either outpatient clinic, emergency or surgery) due to venous disease between April 2006 and December 2019 were identified. PLWHA found to have undergone varicose vein surgery within the study inclusion period were included. The immediately consecutive varicose vein surgery in a patient with no-HIV infection was included in the control group in a 1:1 ratio. Comorbidities were collected at the time of index event. RESULTS: The cohort included 118 patients (59 PLWHA and 59 control) and had a mean follow-up of 86 [Interquartile range (IQR) 25-75%, 43-111] months. At baseline, PLWHA were younger (45.2 ± 10.71 vs 49.9 ± 10.69 years, p=0.017) and had a male predominance (54% vs 27%, p=0.003). Furthermore, there were a higher prevalence of smokers (54% vs 17%, p<0.001) and history of drug abuse (34% vs 2%, p<0.001) in the study group. Although not statistically significant, PLWHA presented higher pre-operative CEAP classifications. Regarding post-operative outcomes, no differences were found for complications, reinterventions or overall-mortality. CONCLUSION: To the authors knowledge, this is the first study addressing varicose vein treatment in PLWHA. In summary, PLWHA undergoing varicose vein surgery seem to be younger and have higher CEAP classifications. Nonetheless, short and long-term outcomes seem to be good and similar to a control population. Further studies with larger populations and disease specific outcomes are necessary to confirm such findings.
publishDate 2023
dc.date.none.fl_str_mv 2023-03-23
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://doi.org/10.48750/acv.492
https://doi.org/10.48750/acv.492
url https://doi.org/10.48750/acv.492
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv http://acvjournal.com/index.php/acv/article/view/492
http://acvjournal.com/index.php/acv/article/view/492/313
dc.rights.driver.fl_str_mv Copyright (c) 2023 Angiologia e Cirurgia Vascular
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2023 Angiologia e Cirurgia Vascular
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Sociedade Portuguesa de Angiologia e Cirurgia Vascular
publisher.none.fl_str_mv Sociedade Portuguesa de Angiologia e Cirurgia Vascular
dc.source.none.fl_str_mv Angiologia e Cirurgia Vascular; Vol. 18 No. 4 (2022): December; 215-218
Angiologia e Cirurgia Vascular; Vol. 18 N.º 4 (2022): December; 215-218
2183-0096
1646-706X
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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