Anaphylaxis to Agaricus bisporus ingestion
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.16/2588 |
Resumo: | A 33-year-old male with house dust mite allergic rhinitis and asthma reported an episode of facial and lip angioedema, dyspnea, cough and dysphagia at the age of 25, minutes after eating a mushroom ( Agaricus bisporus ) pizza. He denied any drug intake, hymenoptera stings or other possible triggers, and no identifiable cofactors were present. Since then he avoided all types of mushrooms, however an accidental contact occurred with mushroom sauce that resulted in angioedema of the lip within minutes. The allergy workup included measurements of total IgE and specific IgE to mushroom, and skin prick test to aeroallergens sources, possible food allergen sources and mushroom extract, a prick to prick test with raw and cooked A. bisporus , in addition to a SDS-PAGE and immunoblotting assay. The study revealed a specific IgE to mushroom of 0.76kUA/L positive skin prick test to mushroom extract, and prick to prick test positive to white and brown A. bisporus (raw and cooked). The immunoblotting identified two IgE binding proteins with 10kDa and 27kDa. We report a case of A. bisporus anaphylaxis probably due to primary mushroom sensitization. We detected two IgE-reactive proteins with 10kDa and 27kDa as possible culprit allergens. |
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Anaphylaxis to Agaricus bisporus ingestionAnaphylaxisAgaricalesImmunoblottingA 33-year-old male with house dust mite allergic rhinitis and asthma reported an episode of facial and lip angioedema, dyspnea, cough and dysphagia at the age of 25, minutes after eating a mushroom ( Agaricus bisporus ) pizza. He denied any drug intake, hymenoptera stings or other possible triggers, and no identifiable cofactors were present. Since then he avoided all types of mushrooms, however an accidental contact occurred with mushroom sauce that resulted in angioedema of the lip within minutes. The allergy workup included measurements of total IgE and specific IgE to mushroom, and skin prick test to aeroallergens sources, possible food allergen sources and mushroom extract, a prick to prick test with raw and cooked A. bisporus , in addition to a SDS-PAGE and immunoblotting assay. The study revealed a specific IgE to mushroom of 0.76kUA/L positive skin prick test to mushroom extract, and prick to prick test positive to white and brown A. bisporus (raw and cooked). The immunoblotting identified two IgE binding proteins with 10kDa and 27kDa. We report a case of A. bisporus anaphylaxis probably due to primary mushroom sensitization. We detected two IgE-reactive proteins with 10kDa and 27kDa as possible culprit allergens.Instituto de Ensino e Pesquisa Albert EinsteinRepositório Científico do Centro Hospitalar Universitário de Santo AntónioCunha, Inês MachadoMarques, Maria LuísAbreu, CarmoBartolomé, Borjagomes, Eva2021-11-22T12:16:58Z2020-11-272020-11-27T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.16/2588engCunha IM, Marques ML, Abreu C, Bartolomé B, Gomes E. Anaphylaxis to Agaricus bisporus ingestion. Einstein (Sao Paulo). 2020;18:eRC5478. doi:10.31744/einstein_journal/2020RC54781679-450810.31744/einstein_journal/2020RC5478info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-10-20T11:01:11Zoai:repositorio.chporto.pt:10400.16/2588Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T20:38:47.203709Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Anaphylaxis to Agaricus bisporus ingestion |
title |
Anaphylaxis to Agaricus bisporus ingestion |
spellingShingle |
Anaphylaxis to Agaricus bisporus ingestion Cunha, Inês Machado Anaphylaxis Agaricales Immunoblotting |
title_short |
Anaphylaxis to Agaricus bisporus ingestion |
title_full |
Anaphylaxis to Agaricus bisporus ingestion |
title_fullStr |
Anaphylaxis to Agaricus bisporus ingestion |
title_full_unstemmed |
Anaphylaxis to Agaricus bisporus ingestion |
title_sort |
Anaphylaxis to Agaricus bisporus ingestion |
author |
Cunha, Inês Machado |
author_facet |
Cunha, Inês Machado Marques, Maria Luís Abreu, Carmo Bartolomé, Borja gomes, Eva |
author_role |
author |
author2 |
Marques, Maria Luís Abreu, Carmo Bartolomé, Borja gomes, Eva |
author2_role |
author author author author |
dc.contributor.none.fl_str_mv |
Repositório Científico do Centro Hospitalar Universitário de Santo António |
dc.contributor.author.fl_str_mv |
Cunha, Inês Machado Marques, Maria Luís Abreu, Carmo Bartolomé, Borja gomes, Eva |
dc.subject.por.fl_str_mv |
Anaphylaxis Agaricales Immunoblotting |
topic |
Anaphylaxis Agaricales Immunoblotting |
description |
A 33-year-old male with house dust mite allergic rhinitis and asthma reported an episode of facial and lip angioedema, dyspnea, cough and dysphagia at the age of 25, minutes after eating a mushroom ( Agaricus bisporus ) pizza. He denied any drug intake, hymenoptera stings or other possible triggers, and no identifiable cofactors were present. Since then he avoided all types of mushrooms, however an accidental contact occurred with mushroom sauce that resulted in angioedema of the lip within minutes. The allergy workup included measurements of total IgE and specific IgE to mushroom, and skin prick test to aeroallergens sources, possible food allergen sources and mushroom extract, a prick to prick test with raw and cooked A. bisporus , in addition to a SDS-PAGE and immunoblotting assay. The study revealed a specific IgE to mushroom of 0.76kUA/L positive skin prick test to mushroom extract, and prick to prick test positive to white and brown A. bisporus (raw and cooked). The immunoblotting identified two IgE binding proteins with 10kDa and 27kDa. We report a case of A. bisporus anaphylaxis probably due to primary mushroom sensitization. We detected two IgE-reactive proteins with 10kDa and 27kDa as possible culprit allergens. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-11-27 2020-11-27T00:00:00Z 2021-11-22T12:16:58Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.16/2588 |
url |
http://hdl.handle.net/10400.16/2588 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Cunha IM, Marques ML, Abreu C, Bartolomé B, Gomes E. Anaphylaxis to Agaricus bisporus ingestion. Einstein (Sao Paulo). 2020;18:eRC5478. doi:10.31744/einstein_journal/2020RC5478 1679-4508 10.31744/einstein_journal/2020RC5478 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Instituto de Ensino e Pesquisa Albert Einstein |
publisher.none.fl_str_mv |
Instituto de Ensino e Pesquisa Albert Einstein |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
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1799133648418504704 |