Psychotic aura symptoms in familial hemiplegic migraine type 2 (ATP1A2)

• Autor(a) principal: Barros, J.
• Data de Publicação: 2012
• Outros Autores: Mendes, A., Matos, I., Pereira-Monteiro, J.
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
• Texto Completo: http://hdl.handle.net/10400.16/1032

Abstract INTRODUCTION: Neuropsychological symptoms are rare in familial hemiplegic migraine (FHM). There are no reports of psychotic symptoms in FHM type 2 (ATP1A2). We examined a family with a FHM phenotype due to a M731T mutation in ATP1A2. A 10-year follow-up allowed us to observe complex auras, including psychotic symptoms in two siblings. CASE REPORT: Male, 48 years old, with an aura that included complex illusions with a feeling of time travelling, coincident with other aura features. The aura was regarded as mystical by the patient. Female, 38 years old, with a complex migraine aura, during which she believed she had the ability to time travel and was being followed by lobbyists who wanted to steal this ability from her. DISCUSSION: FHM type 2 must be included in the list of differential diagnoses of acute psychosis in patients with a previous history of migraine aura.