Measurement of glomerulus diameter and Bowman's space width of renal albino rats
Autor(a) principal: | |
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Data de Publicação: | 2016 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://hdl.handle.net/10216/82986 |
Resumo: | Glomerulus diameter and Bowman's space width in renal microscopic images indicate various diseases. Therefore, the detection of the renal corpuscle and related objects is a key step in histopathological evaluation of renal microscopic images. However, the task of automatic glomeruli detection is challenging due to their wide intensity variation, besides the inconsistency in terms of shape and size of the glomeruli in the renal corpuscle. Here, a novel solution is proposed which includes the Particles Analyzer technique based on median filter for morphological image processing to detect the renal corpuscle objects. Afterwards, the glomerulus diameter and Bowman's space width are measured. The solution was tested with a dataset of 21 rats' renal corpuscle images acquired using light microscope. The experimental results proved that the proposed solution can detect the renal corpuscle and its objects efficiently. As well as, the proposed solution has the ability to manage any input images assuring its robustness to the deformations of the glomeruli even with the glomerular hypertrophy cases. Also, the results reported significant difference between the control and affected (due to ingested additional daily dose (14.6mg) of fructose) groups in terms of glomerulus diameter (97.40 ± 19.02m and 177.03 ± 54.48m, respectively). |
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Measurement of glomerulus diameter and Bowman's space width of renal albino ratsCiências Tecnológicas, Ciências médicas e da saúdeTechnological sciences, Medical and Health sciencesGlomerulus diameter and Bowman's space width in renal microscopic images indicate various diseases. Therefore, the detection of the renal corpuscle and related objects is a key step in histopathological evaluation of renal microscopic images. However, the task of automatic glomeruli detection is challenging due to their wide intensity variation, besides the inconsistency in terms of shape and size of the glomeruli in the renal corpuscle. Here, a novel solution is proposed which includes the Particles Analyzer technique based on median filter for morphological image processing to detect the renal corpuscle objects. Afterwards, the glomerulus diameter and Bowman's space width are measured. The solution was tested with a dataset of 21 rats' renal corpuscle images acquired using light microscope. The experimental results proved that the proposed solution can detect the renal corpuscle and its objects efficiently. As well as, the proposed solution has the ability to manage any input images assuring its robustness to the deformations of the glomeruli even with the glomerular hypertrophy cases. Also, the results reported significant difference between the control and affected (due to ingested additional daily dose (14.6mg) of fructose) groups in terms of glomerulus diameter (97.40 ± 19.02m and 177.03 ± 54.48m, respectively).20162016-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/10216/82986eng0169-260710.1016/j.cmpb.2015.10.023Taras KotykNilanjan DeyAmira S. AshourDana Balas-TimarSayan ChakrabortyAhmed S. AshourJoão Manuel R. S. Tavaresinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-29T14:04:12Zoai:repositorio-aberto.up.pt:10216/82986Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T23:53:56.744301Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Measurement of glomerulus diameter and Bowman's space width of renal albino rats |
title |
Measurement of glomerulus diameter and Bowman's space width of renal albino rats |
spellingShingle |
Measurement of glomerulus diameter and Bowman's space width of renal albino rats Taras Kotyk Ciências Tecnológicas, Ciências médicas e da saúde Technological sciences, Medical and Health sciences |
title_short |
Measurement of glomerulus diameter and Bowman's space width of renal albino rats |
title_full |
Measurement of glomerulus diameter and Bowman's space width of renal albino rats |
title_fullStr |
Measurement of glomerulus diameter and Bowman's space width of renal albino rats |
title_full_unstemmed |
Measurement of glomerulus diameter and Bowman's space width of renal albino rats |
title_sort |
Measurement of glomerulus diameter and Bowman's space width of renal albino rats |
author |
Taras Kotyk |
author_facet |
Taras Kotyk Nilanjan Dey Amira S. Ashour Dana Balas-Timar Sayan Chakraborty Ahmed S. Ashour João Manuel R. S. Tavares |
author_role |
author |
author2 |
Nilanjan Dey Amira S. Ashour Dana Balas-Timar Sayan Chakraborty Ahmed S. Ashour João Manuel R. S. Tavares |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Taras Kotyk Nilanjan Dey Amira S. Ashour Dana Balas-Timar Sayan Chakraborty Ahmed S. Ashour João Manuel R. S. Tavares |
dc.subject.por.fl_str_mv |
Ciências Tecnológicas, Ciências médicas e da saúde Technological sciences, Medical and Health sciences |
topic |
Ciências Tecnológicas, Ciências médicas e da saúde Technological sciences, Medical and Health sciences |
description |
Glomerulus diameter and Bowman's space width in renal microscopic images indicate various diseases. Therefore, the detection of the renal corpuscle and related objects is a key step in histopathological evaluation of renal microscopic images. However, the task of automatic glomeruli detection is challenging due to their wide intensity variation, besides the inconsistency in terms of shape and size of the glomeruli in the renal corpuscle. Here, a novel solution is proposed which includes the Particles Analyzer technique based on median filter for morphological image processing to detect the renal corpuscle objects. Afterwards, the glomerulus diameter and Bowman's space width are measured. The solution was tested with a dataset of 21 rats' renal corpuscle images acquired using light microscope. The experimental results proved that the proposed solution can detect the renal corpuscle and its objects efficiently. As well as, the proposed solution has the ability to manage any input images assuring its robustness to the deformations of the glomeruli even with the glomerular hypertrophy cases. Also, the results reported significant difference between the control and affected (due to ingested additional daily dose (14.6mg) of fructose) groups in terms of glomerulus diameter (97.40 ± 19.02m and 177.03 ± 54.48m, respectively). |
publishDate |
2016 |
dc.date.none.fl_str_mv |
2016 2016-01-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://hdl.handle.net/10216/82986 |
url |
https://hdl.handle.net/10216/82986 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
0169-2607 10.1016/j.cmpb.2015.10.023 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
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1799135859818102785 |