Role of mitochondrial antioxidant defense systems in fatty acid β-oxidation defects

Detalhes bibliográficos
Autor(a) principal: Rocha, Hugo
Data de Publicação: 2012
Outros Autores: Ferreira, Rita, Vitorino, Rui, Almeida, Vanessa, Santa, Cátia, Lopes, Lurdes, Vilarinho, Laura, Amado, Francisco
Tipo de documento: Artigo de conferência
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.18/4042
Resumo: Mitochondrial fatty acid oxidation (FAO) plays a pivotal role in energy homeostasis, namely during periods of fasting or metabolic stress. FAO defects are a group of inherited metabolic disorders that encompass at least twelve distinct enzyme or transporter deficiencies, and can present with a wide range of clinical symptoms with various degrees of severity. Besides recent advances, many doubts still remain on the degree and characteristics of mitochondrial dysfunction on FAOD and its contribution to the clinical phenotype.
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spelling Role of mitochondrial antioxidant defense systems in fatty acid β-oxidation defectsDoenças GenéticasMitochondrial fatty acid oxidationMitochondrial fatty acid oxidation (FAO) plays a pivotal role in energy homeostasis, namely during periods of fasting or metabolic stress. FAO defects are a group of inherited metabolic disorders that encompass at least twelve distinct enzyme or transporter deficiencies, and can present with a wide range of clinical symptoms with various degrees of severity. Besides recent advances, many doubts still remain on the degree and characteristics of mitochondrial dysfunction on FAOD and its contribution to the clinical phenotype.Repositório Científico do Instituto Nacional de SaúdeRocha, HugoFerreira, RitaVitorino, RuiAlmeida, VanessaSanta, CátiaLopes, LurdesVilarinho, LauraAmado, Francisco2016-10-06T15:26:40Z2012-06-062012-06-06T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/conferenceObjectapplication/pdfhttp://hdl.handle.net/10400.18/4042enginfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-20T15:38:40Zoai:repositorio.insa.pt:10400.18/4042Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:36:27.758241Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Role of mitochondrial antioxidant defense systems in fatty acid β-oxidation defects
title Role of mitochondrial antioxidant defense systems in fatty acid β-oxidation defects
spellingShingle Role of mitochondrial antioxidant defense systems in fatty acid β-oxidation defects
Rocha, Hugo
Doenças Genéticas
Mitochondrial fatty acid oxidation
title_short Role of mitochondrial antioxidant defense systems in fatty acid β-oxidation defects
title_full Role of mitochondrial antioxidant defense systems in fatty acid β-oxidation defects
title_fullStr Role of mitochondrial antioxidant defense systems in fatty acid β-oxidation defects
title_full_unstemmed Role of mitochondrial antioxidant defense systems in fatty acid β-oxidation defects
title_sort Role of mitochondrial antioxidant defense systems in fatty acid β-oxidation defects
author Rocha, Hugo
author_facet Rocha, Hugo
Ferreira, Rita
Vitorino, Rui
Almeida, Vanessa
Santa, Cátia
Lopes, Lurdes
Vilarinho, Laura
Amado, Francisco
author_role author
author2 Ferreira, Rita
Vitorino, Rui
Almeida, Vanessa
Santa, Cátia
Lopes, Lurdes
Vilarinho, Laura
Amado, Francisco
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório Científico do Instituto Nacional de Saúde
dc.contributor.author.fl_str_mv Rocha, Hugo
Ferreira, Rita
Vitorino, Rui
Almeida, Vanessa
Santa, Cátia
Lopes, Lurdes
Vilarinho, Laura
Amado, Francisco
dc.subject.por.fl_str_mv Doenças Genéticas
Mitochondrial fatty acid oxidation
topic Doenças Genéticas
Mitochondrial fatty acid oxidation
description Mitochondrial fatty acid oxidation (FAO) plays a pivotal role in energy homeostasis, namely during periods of fasting or metabolic stress. FAO defects are a group of inherited metabolic disorders that encompass at least twelve distinct enzyme or transporter deficiencies, and can present with a wide range of clinical symptoms with various degrees of severity. Besides recent advances, many doubts still remain on the degree and characteristics of mitochondrial dysfunction on FAOD and its contribution to the clinical phenotype.
publishDate 2012
dc.date.none.fl_str_mv 2012-06-06
2012-06-06T00:00:00Z
2016-10-06T15:26:40Z
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dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.18/4042
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dc.language.iso.fl_str_mv eng
language eng
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dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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