Voltammetric and impedance studies of inosine-5'-monophosphate and hypoxanthine

Detalhes bibliográficos
Autor(a) principal: Brett, Ana Maria Oliveira
Data de Publicação: 2003
Outros Autores: Silva, Luís A., Farace, Giosi, Vadgama, Pankaj, Brett, Christopher M. A.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10316/5165
https://doi.org/10.1016/S1567-5394(02)00189-5
Resumo: The oxidation mechanism and adsorption of inosine 5'-monophosphate and hypoxanthine were investigated in solutions of different pH using voltammetric and impedance methods at glassy carbon electrodes. For both compounds, the pH dependence from differential pulse voltammetry showed that the same number of electrons and protons are involved in the rate-determining step of the electrochemical reaction. In the case of hypoxanthine, it was also possible to study the effect of different concentrations. At high concentrations of hypoxanthine, two oxidation peaks were observed, the first due to hypoxanthine oxidation with formation of oligomers and the second due to hypoxanthine oligomer oxidation, both compounds adsorbing strongly. Impedance measurements corroborated the voltammetric results and enabled the study of the adsorption of hypoxanthine on glassy carbon.
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spelling Voltammetric and impedance studies of inosine-5'-monophosphate and hypoxanthineInosine 5'-monophosphateHypoxanthineElectrochemical adsorptionDifferential pulse voltammetryElectrochemical impedanceDNA-biosensorThe oxidation mechanism and adsorption of inosine 5'-monophosphate and hypoxanthine were investigated in solutions of different pH using voltammetric and impedance methods at glassy carbon electrodes. For both compounds, the pH dependence from differential pulse voltammetry showed that the same number of electrons and protons are involved in the rate-determining step of the electrochemical reaction. In the case of hypoxanthine, it was also possible to study the effect of different concentrations. At high concentrations of hypoxanthine, two oxidation peaks were observed, the first due to hypoxanthine oxidation with formation of oligomers and the second due to hypoxanthine oligomer oxidation, both compounds adsorbing strongly. Impedance measurements corroborated the voltammetric results and enabled the study of the adsorption of hypoxanthine on glassy carbon.http://www.sciencedirect.com/science/article/B6W72-47R9YPB-1/1/a6995627364cc875adcae0c8f04fbcd52003info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleaplication/PDFhttp://hdl.handle.net/10316/5165http://hdl.handle.net/10316/5165https://doi.org/10.1016/S1567-5394(02)00189-5engBioelectrochemistry. 59:1-2 (2003) 49-56Brett, Ana Maria OliveiraSilva, Luís A.Farace, GiosiVadgama, PankajBrett, Christopher M. A.info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2020-11-06T16:59:58Zoai:estudogeral.uc.pt:10316/5165Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T21:01:20.164843Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Voltammetric and impedance studies of inosine-5'-monophosphate and hypoxanthine
title Voltammetric and impedance studies of inosine-5'-monophosphate and hypoxanthine
spellingShingle Voltammetric and impedance studies of inosine-5'-monophosphate and hypoxanthine
Brett, Ana Maria Oliveira
Inosine 5'-monophosphate
Hypoxanthine
Electrochemical adsorption
Differential pulse voltammetry
Electrochemical impedance
DNA-biosensor
title_short Voltammetric and impedance studies of inosine-5'-monophosphate and hypoxanthine
title_full Voltammetric and impedance studies of inosine-5'-monophosphate and hypoxanthine
title_fullStr Voltammetric and impedance studies of inosine-5'-monophosphate and hypoxanthine
title_full_unstemmed Voltammetric and impedance studies of inosine-5'-monophosphate and hypoxanthine
title_sort Voltammetric and impedance studies of inosine-5'-monophosphate and hypoxanthine
author Brett, Ana Maria Oliveira
author_facet Brett, Ana Maria Oliveira
Silva, Luís A.
Farace, Giosi
Vadgama, Pankaj
Brett, Christopher M. A.
author_role author
author2 Silva, Luís A.
Farace, Giosi
Vadgama, Pankaj
Brett, Christopher M. A.
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Brett, Ana Maria Oliveira
Silva, Luís A.
Farace, Giosi
Vadgama, Pankaj
Brett, Christopher M. A.
dc.subject.por.fl_str_mv Inosine 5'-monophosphate
Hypoxanthine
Electrochemical adsorption
Differential pulse voltammetry
Electrochemical impedance
DNA-biosensor
topic Inosine 5'-monophosphate
Hypoxanthine
Electrochemical adsorption
Differential pulse voltammetry
Electrochemical impedance
DNA-biosensor
description The oxidation mechanism and adsorption of inosine 5'-monophosphate and hypoxanthine were investigated in solutions of different pH using voltammetric and impedance methods at glassy carbon electrodes. For both compounds, the pH dependence from differential pulse voltammetry showed that the same number of electrons and protons are involved in the rate-determining step of the electrochemical reaction. In the case of hypoxanthine, it was also possible to study the effect of different concentrations. At high concentrations of hypoxanthine, two oxidation peaks were observed, the first due to hypoxanthine oxidation with formation of oligomers and the second due to hypoxanthine oligomer oxidation, both compounds adsorbing strongly. Impedance measurements corroborated the voltammetric results and enabled the study of the adsorption of hypoxanthine on glassy carbon.
publishDate 2003
dc.date.none.fl_str_mv 2003
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10316/5165
http://hdl.handle.net/10316/5165
https://doi.org/10.1016/S1567-5394(02)00189-5
url http://hdl.handle.net/10316/5165
https://doi.org/10.1016/S1567-5394(02)00189-5
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Bioelectrochemistry. 59:1-2 (2003) 49-56
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv aplication/PDF
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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