“Simbiosis” between Gitelman and Pregnancy: a challenge

• Autor(a) principal: Oliveira,Iolanda
• Data de Publicação: 2022
• Outros Autores: Silva,Rui, Pires,Carlos
• Tipo de documento: Relatório
• Idioma: eng
• Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
• Texto Completo: http://scielo.pt/scielo.php?script=sci_arttext&pid=S1646-58302022000100048
• topic: Gitelman’s Syndrome; Pregnancy; Hypokalaemia; Prognosis

Abstract Gitelman's syndrome is characterized by a mutation of SLC12A3 gene, which encodes the NaCl cotransporter of distal convoluted tubule resulting in hypokalaemia. During pregnancy its approach and treatment become a challenge. We report the case of a pregnant woman, with a history of previous abortions, who needed a tight analytical control with several hospital admissions throughout pregnancy and more agressive and controled oral and intravenous therapy, which allowed to preserve a good fetal development and normal delivery without complications. This disease in pregnant women has a good prognosis, although it imposes the need of a tight multidisciplinar follow-up.