An enzymatic route to a benzocarbazole framework using bacterial CotA laccase

Detalhes bibliográficos
Autor(a) principal: Sousa, Ana Catarina
Data de Publicação: 2015
Outros Autores: Piedade, Maria de Fátima M. M., Martins, Lígia O., Robalo, Maria Paula
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.21/5814
Resumo: The CotA laccase-catalysed oxidation of the meta, para-disubstituted arylamine 2,4-diaminophenyldiamine delivers, under mild reaction conditions, a benzocarbazole derivative (1) (74% yield), a key structural motif of a diverse range of applications. This work extends the scope of aromatic frameworks obtained using these enzymes and represents a new efficient and clean method to construct in one step C-C and C-N bonds.
id RCAP_4f283dfa2907edfc438c8dab0c6cb260
oai_identifier_str oai:repositorio.ipl.pt:10400.21/5814
network_acronym_str RCAP
network_name_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository_id_str 7160
spelling An enzymatic route to a benzocarbazole framework using bacterial CotA laccaseActive carbazole alkaloidsTransition-Metal-ComplexesOrganic-SynthesisFungal laccasesAntimicrobial activityBiological evaluationCoupling reactionsBacillus-subtilisDomino reactionsGreen chemistryThe CotA laccase-catalysed oxidation of the meta, para-disubstituted arylamine 2,4-diaminophenyldiamine delivers, under mild reaction conditions, a benzocarbazole derivative (1) (74% yield), a key structural motif of a diverse range of applications. This work extends the scope of aromatic frameworks obtained using these enzymes and represents a new efficient and clean method to construct in one step C-C and C-N bonds.ROYAL SOC CHEMISTRYRCIPLSousa, Ana CatarinaPiedade, Maria de Fátima M. M.Martins, Lígia O.Robalo, Maria Paula2016-03-09T15:31:45Z20152015-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.21/5814engSOUSA, Ana Catarina; [et al.] - An enzymatic route to a benzocarbazole framework using bacterial CotA laccase. Green Chemistry. ISSN. 1463-9262. Vol. 17, N.º 3 (2015), pp. 1429-14331463-926210.1039/c4gc02511cmetadata only accessinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-08-03T09:49:45Zoai:repositorio.ipl.pt:10400.21/5814Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T20:15:02.635231Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv An enzymatic route to a benzocarbazole framework using bacterial CotA laccase
title An enzymatic route to a benzocarbazole framework using bacterial CotA laccase
spellingShingle An enzymatic route to a benzocarbazole framework using bacterial CotA laccase
Sousa, Ana Catarina
Active carbazole alkaloids
Transition-Metal-Complexes
Organic-Synthesis
Fungal laccases
Antimicrobial activity
Biological evaluation
Coupling reactions
Bacillus-subtilis
Domino reactions
Green chemistry
title_short An enzymatic route to a benzocarbazole framework using bacterial CotA laccase
title_full An enzymatic route to a benzocarbazole framework using bacterial CotA laccase
title_fullStr An enzymatic route to a benzocarbazole framework using bacterial CotA laccase
title_full_unstemmed An enzymatic route to a benzocarbazole framework using bacterial CotA laccase
title_sort An enzymatic route to a benzocarbazole framework using bacterial CotA laccase
author Sousa, Ana Catarina
author_facet Sousa, Ana Catarina
Piedade, Maria de Fátima M. M.
Martins, Lígia O.
Robalo, Maria Paula
author_role author
author2 Piedade, Maria de Fátima M. M.
Martins, Lígia O.
Robalo, Maria Paula
author2_role author
author
author
dc.contributor.none.fl_str_mv RCIPL
dc.contributor.author.fl_str_mv Sousa, Ana Catarina
Piedade, Maria de Fátima M. M.
Martins, Lígia O.
Robalo, Maria Paula
dc.subject.por.fl_str_mv Active carbazole alkaloids
Transition-Metal-Complexes
Organic-Synthesis
Fungal laccases
Antimicrobial activity
Biological evaluation
Coupling reactions
Bacillus-subtilis
Domino reactions
Green chemistry
topic Active carbazole alkaloids
Transition-Metal-Complexes
Organic-Synthesis
Fungal laccases
Antimicrobial activity
Biological evaluation
Coupling reactions
Bacillus-subtilis
Domino reactions
Green chemistry
description The CotA laccase-catalysed oxidation of the meta, para-disubstituted arylamine 2,4-diaminophenyldiamine delivers, under mild reaction conditions, a benzocarbazole derivative (1) (74% yield), a key structural motif of a diverse range of applications. This work extends the scope of aromatic frameworks obtained using these enzymes and represents a new efficient and clean method to construct in one step C-C and C-N bonds.
publishDate 2015
dc.date.none.fl_str_mv 2015
2015-01-01T00:00:00Z
2016-03-09T15:31:45Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.21/5814
url http://hdl.handle.net/10400.21/5814
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv SOUSA, Ana Catarina; [et al.] - An enzymatic route to a benzocarbazole framework using bacterial CotA laccase. Green Chemistry. ISSN. 1463-9262. Vol. 17, N.º 3 (2015), pp. 1429-1433
1463-9262
10.1039/c4gc02511c
dc.rights.driver.fl_str_mv metadata only access
info:eu-repo/semantics/openAccess
rights_invalid_str_mv metadata only access
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv ROYAL SOC CHEMISTRY
publisher.none.fl_str_mv ROYAL SOC CHEMISTRY
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
_version_ 1799133408661602304

Registros relacionados