Proof of concept: could snake venoms be a potential source of bioactive compounds for control of mould growth and mycotoxin production

Detalhes bibliográficos
Autor(a) principal: Verheecke-Vaessen, C.
Data de Publicação: 2020
Outros Autores: Monte, Joana, Garcia-Cela, E., Magan, N., Medina, Ana
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/120726
Resumo: Funding Information: This research was funded by a 7th Framework Program, SP3 Support for training and career development of researchers Marie Curie Actions (Project: PIEF-GA-2009-253014) and received support from a BBSRC-SFI research grant (BB/P001432/1) between the Applied Mycology Group at Cranfield University and the School of Biology and Environmental Science, University College Dublin, Ireland.
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spelling Proof of concept: could snake venoms be a potential source of bioactive compounds for control of mould growth and mycotoxin productionApplied Microbiology and BiotechnologyFunding Information: This research was funded by a 7th Framework Program, SP3 Support for training and career development of researchers Marie Curie Actions (Project: PIEF-GA-2009-253014) and received support from a BBSRC-SFI research grant (BB/P001432/1) between the Applied Mycology Group at Cranfield University and the School of Biology and Environmental Science, University College Dublin, Ireland.The objective was to screen 10 snake venoms for their efficacy to control growth and mycotoxin production by important mycotoxigenic fungi including Aspergillus flavus, Aspergillus westerdijkiae, Penicillium verrucosum, Fusarium graminearum and F. langsethiae. The Bioscreen C rapid assay system was used. The venoms from the Viperidae snake family delayed growth of some of the test fungi, especially F. graminearum and F. langsethiae and sometimes A. flavus. Some were also able to reduce mycotoxin production. The two most potent crude snake venoms (Naja nigricollis and N. siamensis; 41 and 43 fractions, respectively) were further fractionated and 83/84 of these fractions were able to reduce mycotoxin production by >90% in two of the mycotoxigenic fungi examined. This study suggests that there may be significant potential for the identification of novel fungistatic/fungicidal bioactive compounds as preservatives of raw and processed food commodities post-harvest from such snake venoms.LAQV@REQUIMTEDQ - Departamento de QuímicaRUNVerheecke-Vaessen, C.Monte, JoanaGarcia-Cela, E.Magan, N.Medina, Ana2021-07-08T22:19:29Z2020-11-012020-11-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article7application/pdfhttp://hdl.handle.net/10362/120726eng0266-8254PURE: 32426535https://doi.org/10.1111/lam.13338info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:03:11Zoai:run.unl.pt:10362/120726Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:44:25.743795Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Proof of concept: could snake venoms be a potential source of bioactive compounds for control of mould growth and mycotoxin production
title Proof of concept: could snake venoms be a potential source of bioactive compounds for control of mould growth and mycotoxin production
spellingShingle Proof of concept: could snake venoms be a potential source of bioactive compounds for control of mould growth and mycotoxin production
Verheecke-Vaessen, C.
Applied Microbiology and Biotechnology
title_short Proof of concept: could snake venoms be a potential source of bioactive compounds for control of mould growth and mycotoxin production
title_full Proof of concept: could snake venoms be a potential source of bioactive compounds for control of mould growth and mycotoxin production
title_fullStr Proof of concept: could snake venoms be a potential source of bioactive compounds for control of mould growth and mycotoxin production
title_full_unstemmed Proof of concept: could snake venoms be a potential source of bioactive compounds for control of mould growth and mycotoxin production
title_sort Proof of concept: could snake venoms be a potential source of bioactive compounds for control of mould growth and mycotoxin production
author Verheecke-Vaessen, C.
author_facet Verheecke-Vaessen, C.
Monte, Joana
Garcia-Cela, E.
Magan, N.
Medina, Ana
author_role author
author2 Monte, Joana
Garcia-Cela, E.
Magan, N.
Medina, Ana
author2_role author
author
author
author
dc.contributor.none.fl_str_mv LAQV@REQUIMTE
DQ - Departamento de Química
RUN
dc.contributor.author.fl_str_mv Verheecke-Vaessen, C.
Monte, Joana
Garcia-Cela, E.
Magan, N.
Medina, Ana
dc.subject.por.fl_str_mv Applied Microbiology and Biotechnology
topic Applied Microbiology and Biotechnology
description Funding Information: This research was funded by a 7th Framework Program, SP3 Support for training and career development of researchers Marie Curie Actions (Project: PIEF-GA-2009-253014) and received support from a BBSRC-SFI research grant (BB/P001432/1) between the Applied Mycology Group at Cranfield University and the School of Biology and Environmental Science, University College Dublin, Ireland.
publishDate 2020
dc.date.none.fl_str_mv 2020-11-01
2020-11-01T00:00:00Z
2021-07-08T22:19:29Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/120726
url http://hdl.handle.net/10362/120726
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 0266-8254
PURE: 32426535
https://doi.org/10.1111/lam.13338
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 7
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dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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