Ensembl regulation resources
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , , , , , , , , , , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.7/589 |
Resumo: | New experimental techniques in epigenomics allow researchers to assay a diversity of highly dynamic features such as histone marks, DNA modifications or chromatin structure. The study of their fluctuations should provide insights into gene expression regulation, cell differentiation and disease. The Ensembl project collects and maintains the Ensembl regulation data resources on epigenetic marks, transcription factor binding and DNA methylation for human and mouse, as well as microarray probe mappings and annotations for a variety of chordate genomes. From this data, we produce a functional annotation of the regulatory elements along the human and mouse genomes with plans to expand to other species as data becomes available. Starting from well-studied cell lines, we will progressively expand our library of measurements to a greater variety of samples. Ensembl's regulation resources provide a central and easy-to-query repository for reference epigenomes. As with all Ensembl data, it is freely available at http://www.ensembl.org, from the Perl and REST APIs and from the public Ensembl MySQL database server at ensembldb.ensembl.org.Database URL: http://www.ensembl.org. |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Ensembl regulation resourcesGenomeDNANew experimental techniques in epigenomics allow researchers to assay a diversity of highly dynamic features such as histone marks, DNA modifications or chromatin structure. The study of their fluctuations should provide insights into gene expression regulation, cell differentiation and disease. The Ensembl project collects and maintains the Ensembl regulation data resources on epigenetic marks, transcription factor binding and DNA methylation for human and mouse, as well as microarray probe mappings and annotations for a variety of chordate genomes. From this data, we produce a functional annotation of the regulatory elements along the human and mouse genomes with plans to expand to other species as data becomes available. Starting from well-studied cell lines, we will progressively expand our library of measurements to a greater variety of samples. Ensembl's regulation resources provide a central and easy-to-query repository for reference epigenomes. As with all Ensembl data, it is freely available at http://www.ensembl.org, from the Perl and REST APIs and from the public Ensembl MySQL database server at ensembldb.ensembl.org.Database URL: http://www.ensembl.org.Wellcome Trust grant: (WT098051); National Human Genome Research Institute grants: (U41HG007234, 1U01 HG004695); Biotechnology and Biological Sciences Research Council grant: (BB/L024225/1); European Molecular Biology Laboratory; European Union’s Seventh Framework Programme; European Research Council.Oxford University PressARCAZerbino, Daniel R.Johnson, NathanJuetteman, ThomasSheppard, DanWilder, Steven P.Lavidas, IliasNuhn, MichaelPerry, EmilyRaffaillac-Desfosses, QuentinSobral, DanielKeefe, DamianGräf, StefanAhmed, IkhlakKinsella, RhodaPritchard, BethanBrent, SimonAmode, RidwanParker, AnneTrevanion, StevenBirney, EwanDunham, IanFlicek, Paul2016-04-27T17:12:27Z2015-11-242015-11-24T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfapplication/vnd.openxmlformats-officedocument.wordprocessingml.documenthttp://hdl.handle.net/10400.7/589engZerbino, D.R., Johnson, N., Juetteman, T. et al. Ensembl regulation resources. Database (2015) Vol. 2015: article ID bav119; doi:10.1093/database/bav11910.1093/database/bav119info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-11-29T14:34:58Zoai:arca.igc.gulbenkian.pt:10400.7/589Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:11:50.228739Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Ensembl regulation resources |
title |
Ensembl regulation resources |
spellingShingle |
Ensembl regulation resources Zerbino, Daniel R. Genome DNA |
title_short |
Ensembl regulation resources |
title_full |
Ensembl regulation resources |
title_fullStr |
Ensembl regulation resources |
title_full_unstemmed |
Ensembl regulation resources |
title_sort |
Ensembl regulation resources |
author |
Zerbino, Daniel R. |
author_facet |
Zerbino, Daniel R. Johnson, Nathan Juetteman, Thomas Sheppard, Dan Wilder, Steven P. Lavidas, Ilias Nuhn, Michael Perry, Emily Raffaillac-Desfosses, Quentin Sobral, Daniel Keefe, Damian Gräf, Stefan Ahmed, Ikhlak Kinsella, Rhoda Pritchard, Bethan Brent, Simon Amode, Ridwan Parker, Anne Trevanion, Steven Birney, Ewan Dunham, Ian Flicek, Paul |
author_role |
author |
author2 |
Johnson, Nathan Juetteman, Thomas Sheppard, Dan Wilder, Steven P. Lavidas, Ilias Nuhn, Michael Perry, Emily Raffaillac-Desfosses, Quentin Sobral, Daniel Keefe, Damian Gräf, Stefan Ahmed, Ikhlak Kinsella, Rhoda Pritchard, Bethan Brent, Simon Amode, Ridwan Parker, Anne Trevanion, Steven Birney, Ewan Dunham, Ian Flicek, Paul |
author2_role |
author author author author author author author author author author author author author author author author author author author author author |
dc.contributor.none.fl_str_mv |
ARCA |
dc.contributor.author.fl_str_mv |
Zerbino, Daniel R. Johnson, Nathan Juetteman, Thomas Sheppard, Dan Wilder, Steven P. Lavidas, Ilias Nuhn, Michael Perry, Emily Raffaillac-Desfosses, Quentin Sobral, Daniel Keefe, Damian Gräf, Stefan Ahmed, Ikhlak Kinsella, Rhoda Pritchard, Bethan Brent, Simon Amode, Ridwan Parker, Anne Trevanion, Steven Birney, Ewan Dunham, Ian Flicek, Paul |
dc.subject.por.fl_str_mv |
Genome DNA |
topic |
Genome DNA |
description |
New experimental techniques in epigenomics allow researchers to assay a diversity of highly dynamic features such as histone marks, DNA modifications or chromatin structure. The study of their fluctuations should provide insights into gene expression regulation, cell differentiation and disease. The Ensembl project collects and maintains the Ensembl regulation data resources on epigenetic marks, transcription factor binding and DNA methylation for human and mouse, as well as microarray probe mappings and annotations for a variety of chordate genomes. From this data, we produce a functional annotation of the regulatory elements along the human and mouse genomes with plans to expand to other species as data becomes available. Starting from well-studied cell lines, we will progressively expand our library of measurements to a greater variety of samples. Ensembl's regulation resources provide a central and easy-to-query repository for reference epigenomes. As with all Ensembl data, it is freely available at http://www.ensembl.org, from the Perl and REST APIs and from the public Ensembl MySQL database server at ensembldb.ensembl.org.Database URL: http://www.ensembl.org. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-11-24 2015-11-24T00:00:00Z 2016-04-27T17:12:27Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.7/589 |
url |
http://hdl.handle.net/10400.7/589 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Zerbino, D.R., Johnson, N., Juetteman, T. et al. Ensembl regulation resources. Database (2015) Vol. 2015: article ID bav119; doi:10.1093/database/bav119 10.1093/database/bav119 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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application/pdf application/vnd.openxmlformats-officedocument.wordprocessingml.document |
dc.publisher.none.fl_str_mv |
Oxford University Press |
publisher.none.fl_str_mv |
Oxford University Press |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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