MYCOPHENOLATE MOFETIL FOR CHILDHOOD ATOPIC ECZEMA

• Autor(a) principal: Guedes, Rita
• Data de Publicação: 2011
• Outros Autores: Leite, Inês, Baptista, Armando, Ferreira, Eduarda Osório
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
• DOI: 10.29021/spdv.69.4.67
• Texto Completo: https://doi.org/10.29021/spdv.69.4.67

Atopic eczema is a chronic inflammatory dermatosis that affects mostly children. In most cases it can be trea- ted with topical therapy, but in a significant number of patients it is necessary to use systemic agents. In some patients side effects associated with long-term systemic treatment and insufficient therapeutic results oblige searching for new therapies. The authors describe a clinical case of a child with severe atopic eczema without a satisfactory response to prescribed therapy. Mycophenolate mofetil was started at 6 years of life, with complete resolution of inflammatory lesions at 5 months of treatment. Therapeutic results presented in this article raise new questions about immunosuppression in atopic dermatitis and suggest a promising therapeutic alternative for cases refractory to classical treatments. To date there is only one published study reporting the treatment with this drug in a small series of pediatric patients.KEYWORDS – Dermatitis, Atopic; Child; Immunosuppressive Agents; Mycophenolic Acid.