Association of dairy product consumption with metabolic and inflammatory biomarkers in adolescents: a cross-Sectional Analysis from the LabMed study
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Outros Autores: | , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/1822/61872 |
Resumo: | This study aimed to investigate the association between dairy product consumption and metabolic and inflammatory biomarkers in Portuguese adolescents, and whether the association differed by weight status. A cross-sectional study was conducted during the school year 2011/2012 with 412 Portuguese adolescents (52.4% girls) in 7th and 10th grade (aged 12 to 18 years old). The World Health Organization cutoffs were used to categorize adolescents as non-overweight (NW) or overweight (OW). Blood samples were collected to analyze C-reactive protein (CRP), interleukin-6 (IL-6), leptin, and adiponectin. Dairy product intake was evaluated using a food frequency questionnaire. Participants were divided by tertiles according to the amount of dairy product consumed. The associations between dairy product consumption with metabolic and inflammatory biomarkers were evaluated using generalized linear regression models with logarithmic link and gamma distribution and adjusted for potential confounders. The majority of adolescents were NW (67.2%). NW adolescents had lower IL-6, CRP, and leptin concentration than their counterparts (<i>p</i> < 0.05, for all comparisons). Higher levels of total dairy product and milk intake were inversely associated with IL-6 (P for trend <0.05, for all) in NW adolescents, but not in OW adolescents. NW adolescents in the second tertile of yogurt consumption had lower level of IL-6 compared to those in the first tertile (<i>p</i> = 0.004). Our results suggest an inverse association between total dairy product and milk intake and serum concentrations of IL-6 only among NW adolescents. |
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Association of dairy product consumption with metabolic and inflammatory biomarkers in adolescents: a cross-Sectional Analysis from the LabMed studydairy productsinflammationadolescentsinflammationScience & TechnologyThis study aimed to investigate the association between dairy product consumption and metabolic and inflammatory biomarkers in Portuguese adolescents, and whether the association differed by weight status. A cross-sectional study was conducted during the school year 2011/2012 with 412 Portuguese adolescents (52.4% girls) in 7th and 10th grade (aged 12 to 18 years old). The World Health Organization cutoffs were used to categorize adolescents as non-overweight (NW) or overweight (OW). Blood samples were collected to analyze C-reactive protein (CRP), interleukin-6 (IL-6), leptin, and adiponectin. Dairy product intake was evaluated using a food frequency questionnaire. Participants were divided by tertiles according to the amount of dairy product consumed. The associations between dairy product consumption with metabolic and inflammatory biomarkers were evaluated using generalized linear regression models with logarithmic link and gamma distribution and adjusted for potential confounders. The majority of adolescents were NW (67.2%). NW adolescents had lower IL-6, CRP, and leptin concentration than their counterparts (<i>p</i> < 0.05, for all comparisons). Higher levels of total dairy product and milk intake were inversely associated with IL-6 (P for trend <0.05, for all) in NW adolescents, but not in OW adolescents. NW adolescents in the second tertile of yogurt consumption had lower level of IL-6 compared to those in the first tertile (<i>p</i> = 0.004). Our results suggest an inverse association between total dairy product and milk intake and serum concentrations of IL-6 only among NW adolescents.This study was supported by the Research Centre on Physical Activity Health and Leisure (CIAFEL) of the Faculty of Sport, University of Porto and by FCT grant BD88984/ 2012 (J. Oliveira-Santos); The Research Centre on Physical Activity Health and Leisure (CIAFEL) is supported by FCT/UID/DTP/00617/2019; the author C. Agostinis-Sobrinho was given Doctoral scholarship from the Brazilian government by CAPES (Coordination of Improvement of Higher Education Personnel) (Proc: 9588-13-2). Rute Santos is founded by and FCT grant (CEECIND/01069/2017). Eduarda Sousa-Sá is funded by a Gulbenkian grant (Project nº 221669-Projeto Academias Gulbenkian do Conhecimento).Multidisciplinary Digital Publishing InstituteUniversidade do MinhoAbreu, SandraAgostinis-Sobrinho, CésarSantos, RuteMoreira, CarlaLopes, LuísGonçalves, CarlaOliveira-Santos, JoséSousa-Sá, EduardaRodrigues, BrunoMota, JorgeRosário, Rafaela2019-09-212019-09-21T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/61872engAbreu, S.; Agostinis-Sobrinho, C.; Santos, R.; Moreira, C.; Lopes, L.; Gonçalves, C.; Oliveira-Santos, J.; Sousa-Sá, E.; Rodrigues, B.; Mota, J.; Rosário, R. Association of Dairy Product Consumption with Metabolic and Inflammatory Biomarkers in Adolescents: A Cross-Sectional Analysis from the LabMed Study. Nutrients. 2019, 11, 2268.2072-664310.3390/nu1110226831546602info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T11:58:56Zoai:repositorium.sdum.uminho.pt:1822/61872Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:48:42.276584Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Association of dairy product consumption with metabolic and inflammatory biomarkers in adolescents: a cross-Sectional Analysis from the LabMed study |
title |
Association of dairy product consumption with metabolic and inflammatory biomarkers in adolescents: a cross-Sectional Analysis from the LabMed study |
spellingShingle |
Association of dairy product consumption with metabolic and inflammatory biomarkers in adolescents: a cross-Sectional Analysis from the LabMed study Abreu, Sandra dairy products inflammation adolescents inflammation Science & Technology |
title_short |
Association of dairy product consumption with metabolic and inflammatory biomarkers in adolescents: a cross-Sectional Analysis from the LabMed study |
title_full |
Association of dairy product consumption with metabolic and inflammatory biomarkers in adolescents: a cross-Sectional Analysis from the LabMed study |
title_fullStr |
Association of dairy product consumption with metabolic and inflammatory biomarkers in adolescents: a cross-Sectional Analysis from the LabMed study |
title_full_unstemmed |
Association of dairy product consumption with metabolic and inflammatory biomarkers in adolescents: a cross-Sectional Analysis from the LabMed study |
title_sort |
Association of dairy product consumption with metabolic and inflammatory biomarkers in adolescents: a cross-Sectional Analysis from the LabMed study |
author |
Abreu, Sandra |
author_facet |
Abreu, Sandra Agostinis-Sobrinho, César Santos, Rute Moreira, Carla Lopes, Luís Gonçalves, Carla Oliveira-Santos, José Sousa-Sá, Eduarda Rodrigues, Bruno Mota, Jorge Rosário, Rafaela |
author_role |
author |
author2 |
Agostinis-Sobrinho, César Santos, Rute Moreira, Carla Lopes, Luís Gonçalves, Carla Oliveira-Santos, José Sousa-Sá, Eduarda Rodrigues, Bruno Mota, Jorge Rosário, Rafaela |
author2_role |
author author author author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade do Minho |
dc.contributor.author.fl_str_mv |
Abreu, Sandra Agostinis-Sobrinho, César Santos, Rute Moreira, Carla Lopes, Luís Gonçalves, Carla Oliveira-Santos, José Sousa-Sá, Eduarda Rodrigues, Bruno Mota, Jorge Rosário, Rafaela |
dc.subject.por.fl_str_mv |
dairy products inflammation adolescents inflammation Science & Technology |
topic |
dairy products inflammation adolescents inflammation Science & Technology |
description |
This study aimed to investigate the association between dairy product consumption and metabolic and inflammatory biomarkers in Portuguese adolescents, and whether the association differed by weight status. A cross-sectional study was conducted during the school year 2011/2012 with 412 Portuguese adolescents (52.4% girls) in 7th and 10th grade (aged 12 to 18 years old). The World Health Organization cutoffs were used to categorize adolescents as non-overweight (NW) or overweight (OW). Blood samples were collected to analyze C-reactive protein (CRP), interleukin-6 (IL-6), leptin, and adiponectin. Dairy product intake was evaluated using a food frequency questionnaire. Participants were divided by tertiles according to the amount of dairy product consumed. The associations between dairy product consumption with metabolic and inflammatory biomarkers were evaluated using generalized linear regression models with logarithmic link and gamma distribution and adjusted for potential confounders. The majority of adolescents were NW (67.2%). NW adolescents had lower IL-6, CRP, and leptin concentration than their counterparts (<i>p</i> < 0.05, for all comparisons). Higher levels of total dairy product and milk intake were inversely associated with IL-6 (P for trend <0.05, for all) in NW adolescents, but not in OW adolescents. NW adolescents in the second tertile of yogurt consumption had lower level of IL-6 compared to those in the first tertile (<i>p</i> = 0.004). Our results suggest an inverse association between total dairy product and milk intake and serum concentrations of IL-6 only among NW adolescents. |
publishDate |
2019 |
dc.date.none.fl_str_mv |
2019-09-21 2019-09-21T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/1822/61872 |
url |
http://hdl.handle.net/1822/61872 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Abreu, S.; Agostinis-Sobrinho, C.; Santos, R.; Moreira, C.; Lopes, L.; Gonçalves, C.; Oliveira-Santos, J.; Sousa-Sá, E.; Rodrigues, B.; Mota, J.; Rosário, R. Association of Dairy Product Consumption with Metabolic and Inflammatory Biomarkers in Adolescents: A Cross-Sectional Analysis from the LabMed Study. Nutrients. 2019, 11, 2268. 2072-6643 10.3390/nu11102268 31546602 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Multidisciplinary Digital Publishing Institute |
publisher.none.fl_str_mv |
Multidisciplinary Digital Publishing Institute |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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