New and efficient bioactive glass compositions for controlling endodontic pathogens

Detalhes bibliográficos
Autor(a) principal: Correia, Bruna L.
Data de Publicação: 2022
Outros Autores: Gomes, Ana T.P.C., Noites, Rita, Ferreira, José M. F., Duarte, Ana S.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.14/37702
Resumo: Endodontic treatment aims to conserve teeth through removing infected tissue, disinfecting, and filling/sealing the root canal. One of the most important treatment steps is the removal of microorganisms to avoid reinfection and consequent tooth loss. Due to increased resistance to intracanal medications, new alternative procedures are needed. Thus, an intracanal medication is suggested using three bioactive glass (BG) compositions (BG1, BG2, and BG3) produced by the sol–gel method, with different molar contents of bactericidal oxides. The BGs were morphologically and physically characterized. Their ability to inhibit the growth of two oral pathogens responsible for the failure of endodontic treatments (E. faecalis and C. albicans) was also studied. The results suggest that BG2 and BG3 can inhibit the growth of E. faecalis after 48 h of incubation, and all BG samples have a significant effect on C. albicans survival.
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spelling New and efficient bioactive glass compositions for controlling endodontic pathogensBioactive glassCandida albicansEnterococcus faecalisIntracanal medicationReinfectionRoot canal treatmentEndodontic treatment aims to conserve teeth through removing infected tissue, disinfecting, and filling/sealing the root canal. One of the most important treatment steps is the removal of microorganisms to avoid reinfection and consequent tooth loss. Due to increased resistance to intracanal medications, new alternative procedures are needed. Thus, an intracanal medication is suggested using three bioactive glass (BG) compositions (BG1, BG2, and BG3) produced by the sol–gel method, with different molar contents of bactericidal oxides. The BGs were morphologically and physically characterized. Their ability to inhibit the growth of two oral pathogens responsible for the failure of endodontic treatments (E. faecalis and C. albicans) was also studied. The results suggest that BG2 and BG3 can inhibit the growth of E. faecalis after 48 h of incubation, and all BG samples have a significant effect on C. albicans survival.Veritati - Repositório Institucional da Universidade Católica PortuguesaCorreia, Bruna L.Gomes, Ana T.P.C.Noites, RitaFerreira, José M. F.Duarte, Ana S.2022-05-24T09:31:41Z2022-05-012022-05-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.14/37702eng2079-499110.3390/nano1209157785129441839PMC910565935564288000794786300001info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-01-16T01:43:47Zoai:repositorio.ucp.pt:10400.14/37702Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:30:42.782821Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv New and efficient bioactive glass compositions for controlling endodontic pathogens
title New and efficient bioactive glass compositions for controlling endodontic pathogens
spellingShingle New and efficient bioactive glass compositions for controlling endodontic pathogens
Correia, Bruna L.
Bioactive glass
Candida albicans
Enterococcus faecalis
Intracanal medication
Reinfection
Root canal treatment
title_short New and efficient bioactive glass compositions for controlling endodontic pathogens
title_full New and efficient bioactive glass compositions for controlling endodontic pathogens
title_fullStr New and efficient bioactive glass compositions for controlling endodontic pathogens
title_full_unstemmed New and efficient bioactive glass compositions for controlling endodontic pathogens
title_sort New and efficient bioactive glass compositions for controlling endodontic pathogens
author Correia, Bruna L.
author_facet Correia, Bruna L.
Gomes, Ana T.P.C.
Noites, Rita
Ferreira, José M. F.
Duarte, Ana S.
author_role author
author2 Gomes, Ana T.P.C.
Noites, Rita
Ferreira, José M. F.
Duarte, Ana S.
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Veritati - Repositório Institucional da Universidade Católica Portuguesa
dc.contributor.author.fl_str_mv Correia, Bruna L.
Gomes, Ana T.P.C.
Noites, Rita
Ferreira, José M. F.
Duarte, Ana S.
dc.subject.por.fl_str_mv Bioactive glass
Candida albicans
Enterococcus faecalis
Intracanal medication
Reinfection
Root canal treatment
topic Bioactive glass
Candida albicans
Enterococcus faecalis
Intracanal medication
Reinfection
Root canal treatment
description Endodontic treatment aims to conserve teeth through removing infected tissue, disinfecting, and filling/sealing the root canal. One of the most important treatment steps is the removal of microorganisms to avoid reinfection and consequent tooth loss. Due to increased resistance to intracanal medications, new alternative procedures are needed. Thus, an intracanal medication is suggested using three bioactive glass (BG) compositions (BG1, BG2, and BG3) produced by the sol–gel method, with different molar contents of bactericidal oxides. The BGs were morphologically and physically characterized. Their ability to inhibit the growth of two oral pathogens responsible for the failure of endodontic treatments (E. faecalis and C. albicans) was also studied. The results suggest that BG2 and BG3 can inhibit the growth of E. faecalis after 48 h of incubation, and all BG samples have a significant effect on C. albicans survival.
publishDate 2022
dc.date.none.fl_str_mv 2022-05-24T09:31:41Z
2022-05-01
2022-05-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.14/37702
url http://hdl.handle.net/10400.14/37702
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 2079-4991
10.3390/nano12091577
85129441839
PMC9105659
35564288
000794786300001
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eu_rights_str_mv openAccess
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instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
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collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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