Global longitudinal strain in chronic asymptomatic aortic regurgitation: systematic review
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10316/105896 https://doi.org/10.1530/ERP-20-0024 |
Resumo: | Chronic aortic regurgitation (AR) patients typically remain asymptomatic for a long time. Left ventricular mechanics, namely global longitudinal strain (GLS), has been associated with outcomes in AR patients. The authors conducted a systematic review to summarize and appraise GLS impact on mortality, the need for aortic valve replacement (AVR) and disease progression in AR patients. A literature search was performed using these key terms 'aortic regurgitation' and 'longitudinal strain' looking at all randomized and nonrandomized studies conducted on chronic aortic regurgitation. The search yielded six observational studies published from 2011 and 2018 with a total of 1571 patients with moderate to severe chronic AR. Only two studies included all-cause mortality as their endpoint. The other studies looked at the association between GLS with AVR and disease progression. The mean follow-up period was 4.2 years. We noted a great variability of clinical, methodological and/or statistical origin. Thus, meta-analytic portion of our study was limited. Despite a relevant heterogeneity, an impaired GLS was associated with adverse cardiac outcomes. Left ventricular GLS may offer incremental value in risk stratification and decision-making. |
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Global longitudinal strain in chronic asymptomatic aortic regurgitation: systematic reviewaortic regurgitationglobal longitudinal strainoutcomesaortic valve replacementChronic aortic regurgitation (AR) patients typically remain asymptomatic for a long time. Left ventricular mechanics, namely global longitudinal strain (GLS), has been associated with outcomes in AR patients. The authors conducted a systematic review to summarize and appraise GLS impact on mortality, the need for aortic valve replacement (AVR) and disease progression in AR patients. A literature search was performed using these key terms 'aortic regurgitation' and 'longitudinal strain' looking at all randomized and nonrandomized studies conducted on chronic aortic regurgitation. The search yielded six observational studies published from 2011 and 2018 with a total of 1571 patients with moderate to severe chronic AR. Only two studies included all-cause mortality as their endpoint. The other studies looked at the association between GLS with AVR and disease progression. The mean follow-up period was 4.2 years. We noted a great variability of clinical, methodological and/or statistical origin. Thus, meta-analytic portion of our study was limited. Despite a relevant heterogeneity, an impaired GLS was associated with adverse cardiac outcomes. Left ventricular GLS may offer incremental value in risk stratification and decision-making.Springer Nature2020-09info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://hdl.handle.net/10316/105896http://hdl.handle.net/10316/105896https://doi.org/10.1530/ERP-20-0024eng2055-0464Campos, DianaTeixeira, RogérioSaleiro, CarolinaBotelho, AnaGonçalves, Linoinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-03-14T21:31:50Zoai:estudogeral.uc.pt:10316/105896Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T21:22:23.328663Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Global longitudinal strain in chronic asymptomatic aortic regurgitation: systematic review |
title |
Global longitudinal strain in chronic asymptomatic aortic regurgitation: systematic review |
spellingShingle |
Global longitudinal strain in chronic asymptomatic aortic regurgitation: systematic review Campos, Diana aortic regurgitation global longitudinal strain outcomes aortic valve replacement |
title_short |
Global longitudinal strain in chronic asymptomatic aortic regurgitation: systematic review |
title_full |
Global longitudinal strain in chronic asymptomatic aortic regurgitation: systematic review |
title_fullStr |
Global longitudinal strain in chronic asymptomatic aortic regurgitation: systematic review |
title_full_unstemmed |
Global longitudinal strain in chronic asymptomatic aortic regurgitation: systematic review |
title_sort |
Global longitudinal strain in chronic asymptomatic aortic regurgitation: systematic review |
author |
Campos, Diana |
author_facet |
Campos, Diana Teixeira, Rogério Saleiro, Carolina Botelho, Ana Gonçalves, Lino |
author_role |
author |
author2 |
Teixeira, Rogério Saleiro, Carolina Botelho, Ana Gonçalves, Lino |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Campos, Diana Teixeira, Rogério Saleiro, Carolina Botelho, Ana Gonçalves, Lino |
dc.subject.por.fl_str_mv |
aortic regurgitation global longitudinal strain outcomes aortic valve replacement |
topic |
aortic regurgitation global longitudinal strain outcomes aortic valve replacement |
description |
Chronic aortic regurgitation (AR) patients typically remain asymptomatic for a long time. Left ventricular mechanics, namely global longitudinal strain (GLS), has been associated with outcomes in AR patients. The authors conducted a systematic review to summarize and appraise GLS impact on mortality, the need for aortic valve replacement (AVR) and disease progression in AR patients. A literature search was performed using these key terms 'aortic regurgitation' and 'longitudinal strain' looking at all randomized and nonrandomized studies conducted on chronic aortic regurgitation. The search yielded six observational studies published from 2011 and 2018 with a total of 1571 patients with moderate to severe chronic AR. Only two studies included all-cause mortality as their endpoint. The other studies looked at the association between GLS with AVR and disease progression. The mean follow-up period was 4.2 years. We noted a great variability of clinical, methodological and/or statistical origin. Thus, meta-analytic portion of our study was limited. Despite a relevant heterogeneity, an impaired GLS was associated with adverse cardiac outcomes. Left ventricular GLS may offer incremental value in risk stratification and decision-making. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-09 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10316/105896 http://hdl.handle.net/10316/105896 https://doi.org/10.1530/ERP-20-0024 |
url |
http://hdl.handle.net/10316/105896 https://doi.org/10.1530/ERP-20-0024 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
2055-0464 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.publisher.none.fl_str_mv |
Springer Nature |
publisher.none.fl_str_mv |
Springer Nature |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799134113500758016 |