The effect of reversible binding sites on drug release from drug eluting stents

Detalhes bibliográficos
Autor(a) principal: Ferreira, José Augusto
Data de Publicação: 2014
Outros Autores: Naghipoor, Jahed, Oliveira, Paula de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10316/44680
Resumo: A coupled non-Fickian model of a cardiovascular drug delivery system using a biodegradable drug eluting stent is proposed. The reversible reaction between the drug and the arterial tissue binding sites are taken into account. The proposed model accounts for the different nature of the therapeutic compounds used. The numerical results are obtained using an IMEX finite element method in the variational form.
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spelling The effect of reversible binding sites on drug release from drug eluting stentsA coupled non-Fickian model of a cardiovascular drug delivery system using a biodegradable drug eluting stent is proposed. The reversible reaction between the drug and the arterial tissue binding sites are taken into account. The proposed model accounts for the different nature of the therapeutic compounds used. The numerical results are obtained using an IMEX finite element method in the variational form.J. Vigo - Aguiar2014info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://hdl.handle.net/10316/44680http://hdl.handle.net/10316/44680enghttp://cmmse.usal.es/cmmse2016/sites/default/files/volumes/Proceedings%20CMMSE-2014-volume2.pdfFerreira, José AugustoNaghipoor, JahedOliveira, Paula deinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2020-05-25T06:28:42Zoai:estudogeral.uc.pt:10316/44680Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T20:53:32.888979Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv The effect of reversible binding sites on drug release from drug eluting stents
title The effect of reversible binding sites on drug release from drug eluting stents
spellingShingle The effect of reversible binding sites on drug release from drug eluting stents
Ferreira, José Augusto
title_short The effect of reversible binding sites on drug release from drug eluting stents
title_full The effect of reversible binding sites on drug release from drug eluting stents
title_fullStr The effect of reversible binding sites on drug release from drug eluting stents
title_full_unstemmed The effect of reversible binding sites on drug release from drug eluting stents
title_sort The effect of reversible binding sites on drug release from drug eluting stents
author Ferreira, José Augusto
author_facet Ferreira, José Augusto
Naghipoor, Jahed
Oliveira, Paula de
author_role author
author2 Naghipoor, Jahed
Oliveira, Paula de
author2_role author
author
dc.contributor.author.fl_str_mv Ferreira, José Augusto
Naghipoor, Jahed
Oliveira, Paula de
description A coupled non-Fickian model of a cardiovascular drug delivery system using a biodegradable drug eluting stent is proposed. The reversible reaction between the drug and the arterial tissue binding sites are taken into account. The proposed model accounts for the different nature of the therapeutic compounds used. The numerical results are obtained using an IMEX finite element method in the variational form.
publishDate 2014
dc.date.none.fl_str_mv 2014
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10316/44680
http://hdl.handle.net/10316/44680
url http://hdl.handle.net/10316/44680
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv http://cmmse.usal.es/cmmse2016/sites/default/files/volumes/Proceedings%20CMMSE-2014-volume2.pdf
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv J. Vigo - Aguiar
publisher.none.fl_str_mv J. Vigo - Aguiar
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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