New method to produce poly(vinyl alcohol)/cellulose acetate films with improved antibacterial action

Detalhes bibliográficos
Autor(a) principal: Felgueiras, Helena Prado
Data de Publicação: 2020
Outros Autores: Teixeira, Marta Albertina, Tavares, Tânia Daniela Eugénio, Amorim, M. T. Pessoa de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://hdl.handle.net/1822/63673
Resumo: New alternatives to the conventional wound dressings are being engineered. Here, we propose the processing of two biodegradable polymers, poly(vinyl alcohol) (PVA) and cellulose acetate (CA), in the form of films via a new method that combines principles of solvent casting and phase-inversion. Highly flexible and mechanically resistant films were obtained. PVA/CA films were then treated with the antibiotic vancomycin via two methods, blending and physisorption (via dopamine). Immobilization of vancomycin was proven efficient in promoting the films' antibacterial action against Staphylococcus epidermidis bacteria. Data demonstrates the potentialities of PVA/CA films for prospective wound healing applications.
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spelling New method to produce poly(vinyl alcohol)/cellulose acetate films with improved antibacterial actionBiodegradable polymersSolvent castingPhase-inversionAntimicrobial peptidesAntibacterial activityWound-healing applicationsEngenharia e Tecnologia::Engenharia dos MateriaisScience & TechnologyNew alternatives to the conventional wound dressings are being engineered. Here, we propose the processing of two biodegradable polymers, poly(vinyl alcohol) (PVA) and cellulose acetate (CA), in the form of films via a new method that combines principles of solvent casting and phase-inversion. Highly flexible and mechanically resistant films were obtained. PVA/CA films were then treated with the antibiotic vancomycin via two methods, blending and physisorption (via dopamine). Immobilization of vancomycin was proven efficient in promoting the films' antibacterial action against Staphylococcus epidermidis bacteria. Data demonstrates the potentialities of PVA/CA films for prospective wound healing applications.Authors acknowledge the Portuguese Foundation for Science and Technology (FCT), FEDER funds by means of Portugal 2020 Competitive Factors Operational Program (POCI) and the Portuguese Government (OE) for funding the project PEPTEX with reference POCI-01-0145-FEDER-028074. Authors also acknowledge project UID/CTM/00264/2019 of Centre for Textile Science and Technology (2C2T), funded by national funds through FCT/MCTESElsevierUniversidade do MinhoFelgueiras, Helena PradoTeixeira, Marta AlbertinaTavares, Tânia Daniela EugénioAmorim, M. T. Pessoa de20202020-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/1822/63673engFelgueiras, H. P., Teixeira, M. A., Tavares, T. D., & Amorim, M. T. P. (2020). New method to produce poly(vinyl alcohol)/cellulose acetate films with improved antibacterial action. Materials Today: Proceedings. Elsevier BV. http://doi.org/10.1016/j.matpr.2019.12.1002214-78532214-785310.1016/j.matpr.2019.12.100https://www.sciencedirect.com/science/article/pii/S2214785319341112info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:30:05ZPortal AgregadorONG
dc.title.none.fl_str_mv New method to produce poly(vinyl alcohol)/cellulose acetate films with improved antibacterial action
title New method to produce poly(vinyl alcohol)/cellulose acetate films with improved antibacterial action
spellingShingle New method to produce poly(vinyl alcohol)/cellulose acetate films with improved antibacterial action
Felgueiras, Helena Prado
Biodegradable polymers
Solvent casting
Phase-inversion
Antimicrobial peptides
Antibacterial activity
Wound-healing applications
Engenharia e Tecnologia::Engenharia dos Materiais
Science & Technology
title_short New method to produce poly(vinyl alcohol)/cellulose acetate films with improved antibacterial action
title_full New method to produce poly(vinyl alcohol)/cellulose acetate films with improved antibacterial action
title_fullStr New method to produce poly(vinyl alcohol)/cellulose acetate films with improved antibacterial action
title_full_unstemmed New method to produce poly(vinyl alcohol)/cellulose acetate films with improved antibacterial action
title_sort New method to produce poly(vinyl alcohol)/cellulose acetate films with improved antibacterial action
author Felgueiras, Helena Prado
author_facet Felgueiras, Helena Prado
Teixeira, Marta Albertina
Tavares, Tânia Daniela Eugénio
Amorim, M. T. Pessoa de
author_role author
author2 Teixeira, Marta Albertina
Tavares, Tânia Daniela Eugénio
Amorim, M. T. Pessoa de
author2_role author
author
author
dc.contributor.none.fl_str_mv Universidade do Minho
dc.contributor.author.fl_str_mv Felgueiras, Helena Prado
Teixeira, Marta Albertina
Tavares, Tânia Daniela Eugénio
Amorim, M. T. Pessoa de
dc.subject.por.fl_str_mv Biodegradable polymers
Solvent casting
Phase-inversion
Antimicrobial peptides
Antibacterial activity
Wound-healing applications
Engenharia e Tecnologia::Engenharia dos Materiais
Science & Technology
topic Biodegradable polymers
Solvent casting
Phase-inversion
Antimicrobial peptides
Antibacterial activity
Wound-healing applications
Engenharia e Tecnologia::Engenharia dos Materiais
Science & Technology
description New alternatives to the conventional wound dressings are being engineered. Here, we propose the processing of two biodegradable polymers, poly(vinyl alcohol) (PVA) and cellulose acetate (CA), in the form of films via a new method that combines principles of solvent casting and phase-inversion. Highly flexible and mechanically resistant films were obtained. PVA/CA films were then treated with the antibiotic vancomycin via two methods, blending and physisorption (via dopamine). Immobilization of vancomycin was proven efficient in promoting the films' antibacterial action against Staphylococcus epidermidis bacteria. Data demonstrates the potentialities of PVA/CA films for prospective wound healing applications.
publishDate 2020
dc.date.none.fl_str_mv 2020
2020-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://hdl.handle.net/1822/63673
url https://hdl.handle.net/1822/63673
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Felgueiras, H. P., Teixeira, M. A., Tavares, T. D., & Amorim, M. T. P. (2020). New method to produce poly(vinyl alcohol)/cellulose acetate films with improved antibacterial action. Materials Today: Proceedings. Elsevier BV. http://doi.org/10.1016/j.matpr.2019.12.100
2214-7853
2214-7853
10.1016/j.matpr.2019.12.100
https://www.sciencedirect.com/science/article/pii/S2214785319341112
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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repository.mail.fl_str_mv
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