Peritoneal dialysis-related peritonitis in 10 years: a single-centre experience
Autor(a) principal: | |
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Data de Publicação: | 2013 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-01692013000100006 |
Resumo: | Aims: Evaluate the incidence, aetiology, predictors and outcomes of peritonitis in our chronic peritoneal dialysis (PD) patients. Patients and methods: A retrospective observational study was carried out in 59 patients during a ten-year period, which included the epidemiology, clinical presentation, microbiology profile, treatment and outcomes of all peritonitis episodes. Results: A total of 88 peritonitis occurred in 31 patients (mean age 43 ±15 years), with a peritonitis rate of 0.57 episodes.patient.year. Male gender (68.0% vs. 39.0%, p < 0.01) was associated with events. Coagulase-negative Staphylococcus was the most frequent agent (25.9%). Staphylococcus aureus peritonitis (17.0%) was associated with repeat peritonitis (44.4% vs. 14.3%, p = 0.02). Nasal carriage of this agent was found in half the patients and five (33.3%) episodes were preceded by exit-site infection. Culture negative peritonitis (15.9%) had lower initial peritoneal leukocyte count (< 1500 cell/mm3: 64.3% vs. 32.4%, p = 0.02). Eleven refractory peritonitis were reported and associated with longer time of treatment (34 vs. 20 days, p < 0.01) and hospital stay (16 vs. 5 days, p < 0.01). The peritoneal catheter was removed in eight cases. Cure was achieved in the majority of cases (n = 80; 90.9%), seven patients were transferred to haemodialysis, and one died. The technique survival rate at 36 months was 80%. Greater risk of peritonitis in the first year was identified in patients transferred from haemodialysis (OR 5.9; CI 95%: 1.2 -29.3) and male gender (OR 5.1; CI 95%: 1.02 - 25.1). Considering all PD patients, first year peritoneal dialysis episode was associated with higher risk for cumulative peritonitis (≥ 3) (OR 10.28; CI 95%: 1.27 -83.32). Diabetes and older age were not associated to higher risk of these events. Conclusion: The overall results of peritonitis episodes were satisfactory. Transfer from haemodialysis and male gender were associated with higher risk for first -year peritonitis. This early event was associated with a greater risk of occurrence of three or more peritonitis in those patients. |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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7160 |
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Peritoneal dialysis-related peritonitis in 10 years: a single-centre experienceOutcomeperitoneal dialysisperitonitispredictorsAims: Evaluate the incidence, aetiology, predictors and outcomes of peritonitis in our chronic peritoneal dialysis (PD) patients. Patients and methods: A retrospective observational study was carried out in 59 patients during a ten-year period, which included the epidemiology, clinical presentation, microbiology profile, treatment and outcomes of all peritonitis episodes. Results: A total of 88 peritonitis occurred in 31 patients (mean age 43 ±15 years), with a peritonitis rate of 0.57 episodes.patient.year. Male gender (68.0% vs. 39.0%, p < 0.01) was associated with events. Coagulase-negative Staphylococcus was the most frequent agent (25.9%). Staphylococcus aureus peritonitis (17.0%) was associated with repeat peritonitis (44.4% vs. 14.3%, p = 0.02). Nasal carriage of this agent was found in half the patients and five (33.3%) episodes were preceded by exit-site infection. Culture negative peritonitis (15.9%) had lower initial peritoneal leukocyte count (< 1500 cell/mm3: 64.3% vs. 32.4%, p = 0.02). Eleven refractory peritonitis were reported and associated with longer time of treatment (34 vs. 20 days, p < 0.01) and hospital stay (16 vs. 5 days, p < 0.01). The peritoneal catheter was removed in eight cases. Cure was achieved in the majority of cases (n = 80; 90.9%), seven patients were transferred to haemodialysis, and one died. The technique survival rate at 36 months was 80%. Greater risk of peritonitis in the first year was identified in patients transferred from haemodialysis (OR 5.9; CI 95%: 1.2 -29.3) and male gender (OR 5.1; CI 95%: 1.02 - 25.1). Considering all PD patients, first year peritoneal dialysis episode was associated with higher risk for cumulative peritonitis (≥ 3) (OR 10.28; CI 95%: 1.27 -83.32). Diabetes and older age were not associated to higher risk of these events. Conclusion: The overall results of peritonitis episodes were satisfactory. Transfer from haemodialysis and male gender were associated with higher risk for first -year peritonitis. This early event was associated with a greater risk of occurrence of three or more peritonitis in those patients.Sociedade Portuguesa de Nefrologia2013-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articletext/htmlhttp://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-01692013000100006Portuguese Journal of Nephrology & Hypertension v.27 n.1 2013reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPenghttp://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-01692013000100006Costa,RuiCastro,RuiOliveira,LuísBento,CláudiaCruz,SandraFructuoso,MónicaPrata,CatarinaMorgado,Teresainfo:eu-repo/semantics/openAccess2024-02-06T17:04:41Zoai:scielo:S0872-01692013000100006Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T02:18:50.027540Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Peritoneal dialysis-related peritonitis in 10 years: a single-centre experience |
title |
Peritoneal dialysis-related peritonitis in 10 years: a single-centre experience |
spellingShingle |
Peritoneal dialysis-related peritonitis in 10 years: a single-centre experience Costa,Rui Outcome peritoneal dialysis peritonitis predictors |
title_short |
Peritoneal dialysis-related peritonitis in 10 years: a single-centre experience |
title_full |
Peritoneal dialysis-related peritonitis in 10 years: a single-centre experience |
title_fullStr |
Peritoneal dialysis-related peritonitis in 10 years: a single-centre experience |
title_full_unstemmed |
Peritoneal dialysis-related peritonitis in 10 years: a single-centre experience |
title_sort |
Peritoneal dialysis-related peritonitis in 10 years: a single-centre experience |
author |
Costa,Rui |
author_facet |
Costa,Rui Castro,Rui Oliveira,Luís Bento,Cláudia Cruz,Sandra Fructuoso,Mónica Prata,Catarina Morgado,Teresa |
author_role |
author |
author2 |
Castro,Rui Oliveira,Luís Bento,Cláudia Cruz,Sandra Fructuoso,Mónica Prata,Catarina Morgado,Teresa |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Costa,Rui Castro,Rui Oliveira,Luís Bento,Cláudia Cruz,Sandra Fructuoso,Mónica Prata,Catarina Morgado,Teresa |
dc.subject.por.fl_str_mv |
Outcome peritoneal dialysis peritonitis predictors |
topic |
Outcome peritoneal dialysis peritonitis predictors |
description |
Aims: Evaluate the incidence, aetiology, predictors and outcomes of peritonitis in our chronic peritoneal dialysis (PD) patients. Patients and methods: A retrospective observational study was carried out in 59 patients during a ten-year period, which included the epidemiology, clinical presentation, microbiology profile, treatment and outcomes of all peritonitis episodes. Results: A total of 88 peritonitis occurred in 31 patients (mean age 43 ±15 years), with a peritonitis rate of 0.57 episodes.patient.year. Male gender (68.0% vs. 39.0%, p < 0.01) was associated with events. Coagulase-negative Staphylococcus was the most frequent agent (25.9%). Staphylococcus aureus peritonitis (17.0%) was associated with repeat peritonitis (44.4% vs. 14.3%, p = 0.02). Nasal carriage of this agent was found in half the patients and five (33.3%) episodes were preceded by exit-site infection. Culture negative peritonitis (15.9%) had lower initial peritoneal leukocyte count (< 1500 cell/mm3: 64.3% vs. 32.4%, p = 0.02). Eleven refractory peritonitis were reported and associated with longer time of treatment (34 vs. 20 days, p < 0.01) and hospital stay (16 vs. 5 days, p < 0.01). The peritoneal catheter was removed in eight cases. Cure was achieved in the majority of cases (n = 80; 90.9%), seven patients were transferred to haemodialysis, and one died. The technique survival rate at 36 months was 80%. Greater risk of peritonitis in the first year was identified in patients transferred from haemodialysis (OR 5.9; CI 95%: 1.2 -29.3) and male gender (OR 5.1; CI 95%: 1.02 - 25.1). Considering all PD patients, first year peritoneal dialysis episode was associated with higher risk for cumulative peritonitis (≥ 3) (OR 10.28; CI 95%: 1.27 -83.32). Diabetes and older age were not associated to higher risk of these events. Conclusion: The overall results of peritonitis episodes were satisfactory. Transfer from haemodialysis and male gender were associated with higher risk for first -year peritonitis. This early event was associated with a greater risk of occurrence of three or more peritonitis in those patients. |
publishDate |
2013 |
dc.date.none.fl_str_mv |
2013-01-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-01692013000100006 |
url |
http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-01692013000100006 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-01692013000100006 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Portuguesa de Nefrologia |
publisher.none.fl_str_mv |
Sociedade Portuguesa de Nefrologia |
dc.source.none.fl_str_mv |
Portuguese Journal of Nephrology & Hypertension v.27 n.1 2013 reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799137278345347072 |