(Un)suitability of the use of pH buffers in biological, biochemical and environmental studies and their interaction with metal ions - a review

Detalhes bibliográficos
Autor(a) principal: Ferreira, Carlos M. H.
Data de Publicação: 2015
Outros Autores: Pinto, Isabel S. S., Soares, Eduardo V., Soares, Helena M. V. M.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/1822/38712
Resumo: The use of buffers to maintain the pH within a desired range is a very common practice in chemical, biochemical and biological studies. Among them, zwitterionic N-substituted aminosulfonic acids, usually known as Good's buffers, although widely used, can complex metals and interact with biological systems. The present work reviews, discusses and updates the metal complexation characteristics of thirty one commercially available buffers. In addition, their impact on biological systems is also presented. The influences of these buffers on the results obtained in biological, biochemical and environmental studies, with special focus on their interaction with metal ions, are highlighted and critically reviewed. Using chemical speciation simulations, based on the current knowledge of the metal-buffer stability constants, a proposal of the most adequate buffer to employ for a given metal ion is presented.
id RCAP_585dc30e99733fa938ab26798f338f92
oai_identifier_str oai:repositorium.sdum.uminho.pt:1822/38712
network_acronym_str RCAP
network_name_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository_id_str 7160
spelling (Un)suitability of the use of pH buffers in biological, biochemical and environmental studies and their interaction with metal ions - a reviewScience & TechnologyThe use of buffers to maintain the pH within a desired range is a very common practice in chemical, biochemical and biological studies. Among them, zwitterionic N-substituted aminosulfonic acids, usually known as Good's buffers, although widely used, can complex metals and interact with biological systems. The present work reviews, discusses and updates the metal complexation characteristics of thirty one commercially available buffers. In addition, their impact on biological systems is also presented. The influences of these buffers on the results obtained in biological, biochemical and environmental studies, with special focus on their interaction with metal ions, are highlighted and critically reviewed. Using chemical speciation simulations, based on the current knowledge of the metal-buffer stability constants, a proposal of the most adequate buffer to employ for a given metal ion is presented.This work has been supported by Fundação para a Ciência e a Tecnologia (FCT), from the Portuguese Government, through the grants Strategic project-LA23/2013-2014 (IBB) and PEST-C/EQB/ LA0006/2011 (REQUIMTE). Soares EV also thanks the Project “BioInd-Biotechnology and Bioengineering for improved Industrial and Agro-Food processes”, REF. NORTE-07-0124-FEDER- 000028 Co-funded by the Programa Operacional Regional do Norte (ON.2 – O Novo Norte), QREN, FEDER.Royal Society of ChemistryUniversidade do MinhoFerreira, Carlos M. H.Pinto, Isabel S. S.Soares, Eduardo V.Soares, Helena M. V. M.20152015-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/38712engFerreira, Carlos M. H.; Pinto, Isabel S. S.; Soares, Eduardo V.; Soares, Helena M. V. M., (Un)suitability of the use of pH buffers in biological, biochemical and environmental studies and their interaction with metal ions - a review. RSC Advances, 5, 30989-31003, 20152046-20692046-206910.1039/C4RA15453Chttp://pubs.rsc.org/en/journals/journalissues/rainfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:08:20Zoai:repositorium.sdum.uminho.pt:1822/38712Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:59:34.070369Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv (Un)suitability of the use of pH buffers in biological, biochemical and environmental studies and their interaction with metal ions - a review
title (Un)suitability of the use of pH buffers in biological, biochemical and environmental studies and their interaction with metal ions - a review
spellingShingle (Un)suitability of the use of pH buffers in biological, biochemical and environmental studies and their interaction with metal ions - a review
Ferreira, Carlos M. H.
Science & Technology
title_short (Un)suitability of the use of pH buffers in biological, biochemical and environmental studies and their interaction with metal ions - a review
title_full (Un)suitability of the use of pH buffers in biological, biochemical and environmental studies and their interaction with metal ions - a review
title_fullStr (Un)suitability of the use of pH buffers in biological, biochemical and environmental studies and their interaction with metal ions - a review
title_full_unstemmed (Un)suitability of the use of pH buffers in biological, biochemical and environmental studies and their interaction with metal ions - a review
title_sort (Un)suitability of the use of pH buffers in biological, biochemical and environmental studies and their interaction with metal ions - a review
author Ferreira, Carlos M. H.
author_facet Ferreira, Carlos M. H.
Pinto, Isabel S. S.
Soares, Eduardo V.
Soares, Helena M. V. M.
author_role author
author2 Pinto, Isabel S. S.
Soares, Eduardo V.
Soares, Helena M. V. M.
author2_role author
author
author
dc.contributor.none.fl_str_mv Universidade do Minho
dc.contributor.author.fl_str_mv Ferreira, Carlos M. H.
Pinto, Isabel S. S.
Soares, Eduardo V.
Soares, Helena M. V. M.
dc.subject.por.fl_str_mv Science & Technology
topic Science & Technology
description The use of buffers to maintain the pH within a desired range is a very common practice in chemical, biochemical and biological studies. Among them, zwitterionic N-substituted aminosulfonic acids, usually known as Good's buffers, although widely used, can complex metals and interact with biological systems. The present work reviews, discusses and updates the metal complexation characteristics of thirty one commercially available buffers. In addition, their impact on biological systems is also presented. The influences of these buffers on the results obtained in biological, biochemical and environmental studies, with special focus on their interaction with metal ions, are highlighted and critically reviewed. Using chemical speciation simulations, based on the current knowledge of the metal-buffer stability constants, a proposal of the most adequate buffer to employ for a given metal ion is presented.
publishDate 2015
dc.date.none.fl_str_mv 2015
2015-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/1822/38712
url http://hdl.handle.net/1822/38712
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Ferreira, Carlos M. H.; Pinto, Isabel S. S.; Soares, Eduardo V.; Soares, Helena M. V. M., (Un)suitability of the use of pH buffers in biological, biochemical and environmental studies and their interaction with metal ions - a review. RSC Advances, 5, 30989-31003, 2015
2046-2069
2046-2069
10.1039/C4RA15453C
http://pubs.rsc.org/en/journals/journalissues/ra
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Royal Society of Chemistry
publisher.none.fl_str_mv Royal Society of Chemistry
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
_version_ 1799132387473358848

Registros relacionados