Stage at presentation of breast cancer in Luanda, Angola - a retrospective study
Autor(a) principal: | |
---|---|
Data de Publicação: | 2015 |
Outros Autores: | , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/1822/41419 |
Resumo: | Background: It is expected that, by 2020, 15 million new cases of cancer will occur every year in the world, one million of them in Africa. Knowledge of cancer trends in African countries is far from adequate, and improvements in cancer prevention efforts are urgently needed. The aim of this study was to characterize breast cancer clinically and pathologically at presentation in Luanda, Angola; we additionally provide quality information that will be useful for breast cancer care planning in the country. Methods: Data on breast cancer cases were retrieved from the Angolan Institute of Cancer Control, from 2006 to 2014. For women diagnosed in 2009 (5-years of follow-up), demographic, clinical and pathological information, at presentation, was collected, namely age at diagnosis, parity, methods used for pathological diagnoses, tumor pathological characteristics, stage of disease and treatment. Descriptive statistics were performed. Results: The median age of women diagnosed with breast cancer in 2009 was 47 years old (range 25–89). The most frequent clinical presentation was breast swelling with axillary lymph nodes metastasis (44.9 %), followed by a mass larger than 5 cm (14.2 %) and lump (12.9 %). Invasive ductal carcinoma was the main histologic type (81.8 %). Only 10.1 % of cancer cases had a well differentiated histological grade. Cancers were diagnosed mostly at advanced stages (66.7 % in stage III and 11.1 % in stage IV). Discussion: In this study, breast cancer was diagnosed at a very advanced stage. Although it reports data from a single cancer center in Luanda, Angola it reinforces the need for early diagnosis and increasing awareness. According to the main challenges related to breast cancer diagnosis and treatment herein presented, we propose a realistic framework that would allow for the implementation of a breast cancer care program, built under a strong network based on cooperation, teaching, audit, good practices and the organization of health services. Conclusion: Angola needs urgently a program for early diagnosis of breast cancer. |
id |
RCAP_5868aa32d95815f1949b82bf34168867 |
---|---|
oai_identifier_str |
oai:repositorium.sdum.uminho.pt:1822/41419 |
network_acronym_str |
RCAP |
network_name_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository_id_str |
7160 |
spelling |
Stage at presentation of breast cancer in Luanda, Angola - a retrospective studyBreast cancerAngolaClinical and pathological characterizationCiências Médicas::Ciências da SaúdeScience & TechnologyBackground: It is expected that, by 2020, 15 million new cases of cancer will occur every year in the world, one million of them in Africa. Knowledge of cancer trends in African countries is far from adequate, and improvements in cancer prevention efforts are urgently needed. The aim of this study was to characterize breast cancer clinically and pathologically at presentation in Luanda, Angola; we additionally provide quality information that will be useful for breast cancer care planning in the country. Methods: Data on breast cancer cases were retrieved from the Angolan Institute of Cancer Control, from 2006 to 2014. For women diagnosed in 2009 (5-years of follow-up), demographic, clinical and pathological information, at presentation, was collected, namely age at diagnosis, parity, methods used for pathological diagnoses, tumor pathological characteristics, stage of disease and treatment. Descriptive statistics were performed. Results: The median age of women diagnosed with breast cancer in 2009 was 47 years old (range 25–89). The most frequent clinical presentation was breast swelling with axillary lymph nodes metastasis (44.9 %), followed by a mass larger than 5 cm (14.2 %) and lump (12.9 %). Invasive ductal carcinoma was the main histologic type (81.8 %). Only 10.1 % of cancer cases had a well differentiated histological grade. Cancers were diagnosed mostly at advanced stages (66.7 % in stage III and 11.1 % in stage IV). Discussion: In this study, breast cancer was diagnosed at a very advanced stage. Although it reports data from a single cancer center in Luanda, Angola it reinforces the need for early diagnosis and increasing awareness. According to the main challenges related to breast cancer diagnosis and treatment herein presented, we propose a realistic framework that would allow for the implementation of a breast cancer care program, built under a strong network based on cooperation, teaching, audit, good practices and the organization of health services. Conclusion: Angola needs urgently a program for early diagnosis of breast cancer.We thank Susana Santos for correction of the article in English language, and a Cancer Registry Staff from IACC, particularly Pedro Luis Hernandez Gonzalez, Paulo Ernesto Alves, Xacu Parica and Alberto Sivi Lutumba for their support in data acquisition. We also thank SEMED -Portugal in support for publication.BioMed Central (BMC)Universidade do MinhoLopes, Lygia VieiraMiguel, FernandoFreitas, HelgaTavares, AntónioPangui, SalvadorCastro, ClaraLacerda, Gonçalo ForjazLongatto Filho, AdhemarWeiderpass, ElisabeteSantos, Lúcio Lara20152015-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/41419engLopes, L. V., Miguel, F., Freitas, H., Tavares, A., Pangui, S., Castro, C., . . . Santos, L. L. (2015). Stage at presentation of breast cancer in Luanda, Angola - a retrospective study. Bmc Health Services Research, 15. doi: 10.1186/s12913-015-1092-91472-696310.1186/s12913-015-1092-926471845http://bmchealthservres.biomedcentral.com/articles/10.1186/s12913-015-1092-9info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:47:48Zoai:repositorium.sdum.uminho.pt:1822/41419Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T19:45:55.891708Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Stage at presentation of breast cancer in Luanda, Angola - a retrospective study |
title |
Stage at presentation of breast cancer in Luanda, Angola - a retrospective study |
spellingShingle |
Stage at presentation of breast cancer in Luanda, Angola - a retrospective study Lopes, Lygia Vieira Breast cancer Angola Clinical and pathological characterization Ciências Médicas::Ciências da Saúde Science & Technology |
title_short |
Stage at presentation of breast cancer in Luanda, Angola - a retrospective study |
title_full |
Stage at presentation of breast cancer in Luanda, Angola - a retrospective study |
title_fullStr |
Stage at presentation of breast cancer in Luanda, Angola - a retrospective study |
title_full_unstemmed |
Stage at presentation of breast cancer in Luanda, Angola - a retrospective study |
title_sort |
Stage at presentation of breast cancer in Luanda, Angola - a retrospective study |
author |
Lopes, Lygia Vieira |
author_facet |
Lopes, Lygia Vieira Miguel, Fernando Freitas, Helga Tavares, António Pangui, Salvador Castro, Clara Lacerda, Gonçalo Forjaz Longatto Filho, Adhemar Weiderpass, Elisabete Santos, Lúcio Lara |
author_role |
author |
author2 |
Miguel, Fernando Freitas, Helga Tavares, António Pangui, Salvador Castro, Clara Lacerda, Gonçalo Forjaz Longatto Filho, Adhemar Weiderpass, Elisabete Santos, Lúcio Lara |
author2_role |
author author author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade do Minho |
dc.contributor.author.fl_str_mv |
Lopes, Lygia Vieira Miguel, Fernando Freitas, Helga Tavares, António Pangui, Salvador Castro, Clara Lacerda, Gonçalo Forjaz Longatto Filho, Adhemar Weiderpass, Elisabete Santos, Lúcio Lara |
dc.subject.por.fl_str_mv |
Breast cancer Angola Clinical and pathological characterization Ciências Médicas::Ciências da Saúde Science & Technology |
topic |
Breast cancer Angola Clinical and pathological characterization Ciências Médicas::Ciências da Saúde Science & Technology |
description |
Background: It is expected that, by 2020, 15 million new cases of cancer will occur every year in the world, one million of them in Africa. Knowledge of cancer trends in African countries is far from adequate, and improvements in cancer prevention efforts are urgently needed. The aim of this study was to characterize breast cancer clinically and pathologically at presentation in Luanda, Angola; we additionally provide quality information that will be useful for breast cancer care planning in the country. Methods: Data on breast cancer cases were retrieved from the Angolan Institute of Cancer Control, from 2006 to 2014. For women diagnosed in 2009 (5-years of follow-up), demographic, clinical and pathological information, at presentation, was collected, namely age at diagnosis, parity, methods used for pathological diagnoses, tumor pathological characteristics, stage of disease and treatment. Descriptive statistics were performed. Results: The median age of women diagnosed with breast cancer in 2009 was 47 years old (range 25–89). The most frequent clinical presentation was breast swelling with axillary lymph nodes metastasis (44.9 %), followed by a mass larger than 5 cm (14.2 %) and lump (12.9 %). Invasive ductal carcinoma was the main histologic type (81.8 %). Only 10.1 % of cancer cases had a well differentiated histological grade. Cancers were diagnosed mostly at advanced stages (66.7 % in stage III and 11.1 % in stage IV). Discussion: In this study, breast cancer was diagnosed at a very advanced stage. Although it reports data from a single cancer center in Luanda, Angola it reinforces the need for early diagnosis and increasing awareness. According to the main challenges related to breast cancer diagnosis and treatment herein presented, we propose a realistic framework that would allow for the implementation of a breast cancer care program, built under a strong network based on cooperation, teaching, audit, good practices and the organization of health services. Conclusion: Angola needs urgently a program for early diagnosis of breast cancer. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015 2015-01-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/1822/41419 |
url |
http://hdl.handle.net/1822/41419 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Lopes, L. V., Miguel, F., Freitas, H., Tavares, A., Pangui, S., Castro, C., . . . Santos, L. L. (2015). Stage at presentation of breast cancer in Luanda, Angola - a retrospective study. Bmc Health Services Research, 15. doi: 10.1186/s12913-015-1092-9 1472-6963 10.1186/s12913-015-1092-9 26471845 http://bmchealthservres.biomedcentral.com/articles/10.1186/s12913-015-1092-9 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
BioMed Central (BMC) |
publisher.none.fl_str_mv |
BioMed Central (BMC) |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
|
_version_ |
1799133025551777792 |