Oxygen Leukocyte Larceny

Detalhes bibliográficos
Autor(a) principal: Pinto da Costa, Miguel
Data de Publicação: 2016
Outros Autores: Pimenta Coelho, Henrique
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/6874
Resumo: The authors present a case of a 60-year-old male patient, previously diagnosed with B-cell chronic lymphocytic leukemia, who was admitted to the Emergency Room with dyspnea. The initial evaluation revealed severe anemia (Hgb = 5.0 g/dL) with hyperleukocytosis (800.000/µL), nearly all of the cells being mature lymphocytes, a normal chest X-ray and a low arterial oxygen saturation (89%; pulse oximetry). After red blood cell transfusion, Hgb values rose (9.0 g/dL) and there was a complete reversion of the dyspnea. Yet, subsequent arterial blood gas analysis, without the administration of supplemental oxygen, systematically revealed very low oxygen saturation values (~ 46%), which was inconsistent with the patient’s clinical state and his pulse oximetry values (~ 87%), and these values were not corrected by the administration of oxygen via non-rebreather mask. The investigation performed allowed to establish the diagnosis of oxygen leukocyte larceny, a phenomenon which conceals the true oxygen saturation due to peripheral consumption by leukocytes.
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spelling Oxygen Leukocyte LarcenySequestro Leucocitário de OxigénioAnoxiaLeukocytosisOxygen ConsumptionOximetry.AnoxiaConsumo de OxigénioLeucocitoseOximetria.The authors present a case of a 60-year-old male patient, previously diagnosed with B-cell chronic lymphocytic leukemia, who was admitted to the Emergency Room with dyspnea. The initial evaluation revealed severe anemia (Hgb = 5.0 g/dL) with hyperleukocytosis (800.000/µL), nearly all of the cells being mature lymphocytes, a normal chest X-ray and a low arterial oxygen saturation (89%; pulse oximetry). After red blood cell transfusion, Hgb values rose (9.0 g/dL) and there was a complete reversion of the dyspnea. Yet, subsequent arterial blood gas analysis, without the administration of supplemental oxygen, systematically revealed very low oxygen saturation values (~ 46%), which was inconsistent with the patient’s clinical state and his pulse oximetry values (~ 87%), and these values were not corrected by the administration of oxygen via non-rebreather mask. The investigation performed allowed to establish the diagnosis of oxygen leukocyte larceny, a phenomenon which conceals the true oxygen saturation due to peripheral consumption by leukocytes.Os autores apresentam um caso clínico de um homem de 60 anos, com diagnóstico de leucemia linfocítica crónica-B, observado no Serviço de Urgência por dispneia de esforço. Na avaliação inicial, destacava-se uma anemia grave (Hgb = 5,0 g/dL) e hiperleucocitose (800 000/µL), correspondendo na sua quase totalidade a linfócitos maduros, uma radiografia do tórax normal e uma saturação de oxigénio baixa (89%). Após transfusão de glóbulos rubros registou-se uma elevação do valor de Hgb (9,0 g/dL) e uma reversão completa do quadro de dispneia. Porém, as gasimetrias subsequentes de reavaliação, em ar ambiente, revelaram sistematicamente valores de saturação de oxigénio muito baixos (~ 46%), discrepantes com o estado clínico do doente e com a oximetria de pulso (~ 87%), e não sofreram qualquer alteração com administração de concentrações de oxigénio por máscara. A investigação efetuada permitiu estabelecer o diagnóstico de sequestro leucocitário de oxigénio, fenómeno que mascara a verdadeira saturação de oxigénio por consumo periférico pelos leucócitos. Ordem dos Médicos2016-05-31info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfimage/jpegimage/jpegapplication/mswordimage/jpegimage/x-ms-bmpimage/jpegapplication/pdfapplication/pdfimage/jpegimage/jpegimage/jpegimage/jpeghttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/6874oai:ojs.www.actamedicaportuguesa.com:article/6874Acta Médica Portuguesa; Vol. 29 No. 5 (2016): May; 343-347Acta Médica Portuguesa; Vol. 29 N.º 5 (2016): Maio; 343-3471646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/6874https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/6874/4688https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/6874/7820https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/6874/7821https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/6874/8047https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/6874/8048https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/6874/8049https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/6874/8050https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/6874/8428https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/6874/8429https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/6874/8482https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/6874/8483https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/6874/8484https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/6874/8485Direitos de Autor (c) 2016 Acta Médica Portuguesa - Ordem dos Médicosinfo:eu-repo/semantics/openAccessPinto da Costa, MiguelPimenta Coelho, Henrique2022-12-20T11:05:01Zoai:ojs.www.actamedicaportuguesa.com:article/6874Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:19:22.890488Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Oxygen Leukocyte Larceny
Sequestro Leucocitário de Oxigénio
title Oxygen Leukocyte Larceny
spellingShingle Oxygen Leukocyte Larceny
Pinto da Costa, Miguel
Anoxia
Leukocytosis
Oxygen Consumption
Oximetry.
Anoxia
Consumo de Oxigénio
Leucocitose
Oximetria.
title_short Oxygen Leukocyte Larceny
title_full Oxygen Leukocyte Larceny
title_fullStr Oxygen Leukocyte Larceny
title_full_unstemmed Oxygen Leukocyte Larceny
title_sort Oxygen Leukocyte Larceny
author Pinto da Costa, Miguel
author_facet Pinto da Costa, Miguel
Pimenta Coelho, Henrique
author_role author
author2 Pimenta Coelho, Henrique
author2_role author
dc.contributor.author.fl_str_mv Pinto da Costa, Miguel
Pimenta Coelho, Henrique
dc.subject.por.fl_str_mv Anoxia
Leukocytosis
Oxygen Consumption
Oximetry.
Anoxia
Consumo de Oxigénio
Leucocitose
Oximetria.
topic Anoxia
Leukocytosis
Oxygen Consumption
Oximetry.
Anoxia
Consumo de Oxigénio
Leucocitose
Oximetria.
description The authors present a case of a 60-year-old male patient, previously diagnosed with B-cell chronic lymphocytic leukemia, who was admitted to the Emergency Room with dyspnea. The initial evaluation revealed severe anemia (Hgb = 5.0 g/dL) with hyperleukocytosis (800.000/µL), nearly all of the cells being mature lymphocytes, a normal chest X-ray and a low arterial oxygen saturation (89%; pulse oximetry). After red blood cell transfusion, Hgb values rose (9.0 g/dL) and there was a complete reversion of the dyspnea. Yet, subsequent arterial blood gas analysis, without the administration of supplemental oxygen, systematically revealed very low oxygen saturation values (~ 46%), which was inconsistent with the patient’s clinical state and his pulse oximetry values (~ 87%), and these values were not corrected by the administration of oxygen via non-rebreather mask. The investigation performed allowed to establish the diagnosis of oxygen leukocyte larceny, a phenomenon which conceals the true oxygen saturation due to peripheral consumption by leukocytes.
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dc.rights.driver.fl_str_mv Direitos de Autor (c) 2016 Acta Médica Portuguesa - Ordem dos Médicos
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dc.publisher.none.fl_str_mv Ordem dos Médicos
publisher.none.fl_str_mv Ordem dos Médicos
dc.source.none.fl_str_mv Acta Médica Portuguesa; Vol. 29 No. 5 (2016): May; 343-347
Acta Médica Portuguesa; Vol. 29 N.º 5 (2016): Maio; 343-347
1646-0758
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