Cytotoxicity of Clay-TiO2 nanostructures in human HepG2 cells

Detalhes bibliográficos
Autor(a) principal: Bessa, Maria João
Data de Publicação: 2015
Outros Autores: Reinosa, Julian Jimenez, Fernandez, José Francisco, Banares, Miguel, Teixeira, João Paulo, Costa, Carla
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.18/3566
Resumo: Background and Objective: In the last decades, nanotechnology has become increasingly attractive to different scientific and industrial fields as it becomes evident that manufactured nanomaterials offer a whole new range of potentialities. On the other hand, different studies have been showing that nanomaterials can be toxic and therefore may harm both the environment and the human health. Recent advances in the production of nanomaterials lead to the development of new structures, namely of nanoparticles immobilized in microstructures that by presenting new physico-chemical features must be test in regards to their toxic potential. Therefore, the aim of the present work was the evaluation of the in vitro cytotoxicity of TiO2 nanoparticles (TiO2 NPs) immobilized in clay (C-TiO2 ) in a hepatocellular carcinoma human cell line (HepG2). In order to understand the origin of the observed effects, TiO2 NPs and clay alone were also studied.
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spelling Cytotoxicity of Clay-TiO2 nanostructures in human HepG2 cellsCytotoxicityNanomaterialsNanotechnologyGenotoxicidade AmbientalBackground and Objective: In the last decades, nanotechnology has become increasingly attractive to different scientific and industrial fields as it becomes evident that manufactured nanomaterials offer a whole new range of potentialities. On the other hand, different studies have been showing that nanomaterials can be toxic and therefore may harm both the environment and the human health. Recent advances in the production of nanomaterials lead to the development of new structures, namely of nanoparticles immobilized in microstructures that by presenting new physico-chemical features must be test in regards to their toxic potential. Therefore, the aim of the present work was the evaluation of the in vitro cytotoxicity of TiO2 nanoparticles (TiO2 NPs) immobilized in clay (C-TiO2 ) in a hepatocellular carcinoma human cell line (HepG2). In order to understand the origin of the observed effects, TiO2 NPs and clay alone were also studied.This work was supported by TD1204 MODENA COST ActionRepositório Científico do Instituto Nacional de SaúdeBessa, Maria JoãoReinosa, Julian JimenezFernandez, José FranciscoBanares, MiguelTeixeira, João PauloCosta, Carla2019-01-01T01:30:10Z20152015-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.18/3566enginfo:eu-repo/semantics/embargoedAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-20T15:39:47ZPortal AgregadorONG
dc.title.none.fl_str_mv Cytotoxicity of Clay-TiO2 nanostructures in human HepG2 cells
title Cytotoxicity of Clay-TiO2 nanostructures in human HepG2 cells
spellingShingle Cytotoxicity of Clay-TiO2 nanostructures in human HepG2 cells
Bessa, Maria João
Cytotoxicity
Nanomaterials
Nanotechnology
Genotoxicidade Ambiental
title_short Cytotoxicity of Clay-TiO2 nanostructures in human HepG2 cells
title_full Cytotoxicity of Clay-TiO2 nanostructures in human HepG2 cells
title_fullStr Cytotoxicity of Clay-TiO2 nanostructures in human HepG2 cells
title_full_unstemmed Cytotoxicity of Clay-TiO2 nanostructures in human HepG2 cells
title_sort Cytotoxicity of Clay-TiO2 nanostructures in human HepG2 cells
author Bessa, Maria João
author_facet Bessa, Maria João
Reinosa, Julian Jimenez
Fernandez, José Francisco
Banares, Miguel
Teixeira, João Paulo
Costa, Carla
author_role author
author2 Reinosa, Julian Jimenez
Fernandez, José Francisco
Banares, Miguel
Teixeira, João Paulo
Costa, Carla
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório Científico do Instituto Nacional de Saúde
dc.contributor.author.fl_str_mv Bessa, Maria João
Reinosa, Julian Jimenez
Fernandez, José Francisco
Banares, Miguel
Teixeira, João Paulo
Costa, Carla
dc.subject.por.fl_str_mv Cytotoxicity
Nanomaterials
Nanotechnology
Genotoxicidade Ambiental
topic Cytotoxicity
Nanomaterials
Nanotechnology
Genotoxicidade Ambiental
description Background and Objective: In the last decades, nanotechnology has become increasingly attractive to different scientific and industrial fields as it becomes evident that manufactured nanomaterials offer a whole new range of potentialities. On the other hand, different studies have been showing that nanomaterials can be toxic and therefore may harm both the environment and the human health. Recent advances in the production of nanomaterials lead to the development of new structures, namely of nanoparticles immobilized in microstructures that by presenting new physico-chemical features must be test in regards to their toxic potential. Therefore, the aim of the present work was the evaluation of the in vitro cytotoxicity of TiO2 nanoparticles (TiO2 NPs) immobilized in clay (C-TiO2 ) in a hepatocellular carcinoma human cell line (HepG2). In order to understand the origin of the observed effects, TiO2 NPs and clay alone were also studied.
publishDate 2015
dc.date.none.fl_str_mv 2015
2015-01-01T00:00:00Z
2019-01-01T01:30:10Z
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dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.18/3566
url http://hdl.handle.net/10400.18/3566
dc.language.iso.fl_str_mv eng
language eng
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dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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