Acute Chagas disease associated with ingestion of contaminated food in Brazilian western Amazon
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2023 |
| Outros Autores: | , , , , , , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
| Texto Completo: | http://hdl.handle.net/10362/154768 |
Resumo: | Funding Information: We would like to thank the following institutions for all the support they accorded: Fundação de Medicina Tropical Dr. Heitor Vieira Dourado, Amazonas Health Surveillance Foundation Dr. Rosimary Costa Pinto (FVS‐RCP/AM), the Municipal Health Departments of the affected by the outbreaks and Fundação de Amparo à Pesquisa do Estado do Amazonas for their financial support in acquiring materials for the molecular detection of the parasite. We would also like to thank the public health surveillance teams and the patients who agreed to participate in this study. Publisher Copyright: © 2023 Belgian Society of Tropical Medicine and the Prince Leopold Institute of Tropical Medicine. |
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Acute Chagas disease associated with ingestion of contaminated food in Brazilian western AmazonAçaíChagas disease outbreaks, clinical epidemiologyoral transmissionTrypanosoma cruziRA0421 Public health. Hygiene. Preventive MedicineRZ Other systems of medicineParasitologyPublic Health, Environmental and Occupational HealthInfectious DiseasesFood ScienceSDG 3 - Good Health and Well-beingSDG 2 - Zero HungerSDG 10 - Reduced InequalitiesFunding Information: We would like to thank the following institutions for all the support they accorded: Fundação de Medicina Tropical Dr. Heitor Vieira Dourado, Amazonas Health Surveillance Foundation Dr. Rosimary Costa Pinto (FVS‐RCP/AM), the Municipal Health Departments of the affected by the outbreaks and Fundação de Amparo à Pesquisa do Estado do Amazonas for their financial support in acquiring materials for the molecular detection of the parasite. We would also like to thank the public health surveillance teams and the patients who agreed to participate in this study. Publisher Copyright: © 2023 Belgian Society of Tropical Medicine and the Prince Leopold Institute of Tropical Medicine.Objective: To describe clinical, epidemiological and management information on cases of acute Chagas disease (ACD) by oral transmission in the state of Amazonas in western Amazon. Methods: Manual and electronic medical records of patients diagnosed with ACD at the Fundação de Medicina Tropical Doutor Heitor Vieira Dourado (FMT-HVD) were included. Results: There were 147 cases of acute CD registered from 10 outbreaks that occurred in the state of Amazonas between 2004 and 2022. The transmission pathway was through oral route, with probable contaminated palm fruit juice (açaí and/or papatuá), and involved people from the same family, friends or neighbours. Of 147 identified cases, 87 (59%) were males; cases were aged 10 months to 82 years. The most common symptom was the febrile syndrome (123/147; 91.8%); cardiac alterations were present in 33/100 (33%), (2/147; 1.4%) had severe ACD with meningoencephalitis, and 12 (8.2%) were asymptomatic. Most cases were diagnosed through thick blood smear (132/147; 89.8%), a few (14/147; 9.5%) were diagnosed by serology and (1/147; 0.7%) by polymerase chain reaction (PCR) and blood culture. In all these outbreaks, 74.1% of the patients were analysed by PCR, and Trypanosoma cruzi TcIV was detected in all of them. No deaths were recorded. The incidence of these foci coincided with the fruit harvest period in the state of Amazonas. Conclusion: The occurrence of ACD outbreaks in the Amazon affected individuals of both sexes, young adults, living in rural and peri-urban areas and related to the consumption of regional foods. Early diagnosis is an important factor in surveillance. There was a low frequency of cardiac alterations. Continuous follow-up of most patients was not carried out due to difficulty in getting to specialised centres; therefore, little is known about post-treatment.Vector borne diseases and pathogens (VBD)Global Health and Tropical Medicine (GHTM)Instituto de Higiene e Medicina Tropical (IHMT)RUNde Sousa, Débora Raysa Teixeirade Oliveira Guerra, Jorge AugustoOrtiz, Jessica Vaninado Nascimento Couceiro, Katiada Silva e Silva, Monica Regina HosanahhJorge Brandão, Alba ReginaGuevara, ElsaArcanjo, Ana Ruth Limade Oliveira Júnior, Edival FerreiraSmith-Doria, SusanMwangi, Victor IrunguMorais, Rômulo FreireSilva, George Allan VillaroucoMolina, IsraelSilveira, HenriqueFerreira, João Marcos Bemfica BarbosaGuerra, Maria das Graças Vale Barbosa2023-07-03T22:16:45Z20232023-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10application/pdfhttp://hdl.handle.net/10362/154768eng1360-2276PURE: 65014153https://doi.org/10.1111/tmi.13899info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:37:12Zoai:run.unl.pt:10362/154768Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:55:44.637479Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
| dc.title.none.fl_str_mv |
Acute Chagas disease associated with ingestion of contaminated food in Brazilian western Amazon |
| title |
Acute Chagas disease associated with ingestion of contaminated food in Brazilian western Amazon |
| spellingShingle |
Acute Chagas disease associated with ingestion of contaminated food in Brazilian western Amazon de Sousa, Débora Raysa Teixeira Açaí Chagas disease outbreaks, clinical epidemiology oral transmission Trypanosoma cruzi RA0421 Public health. Hygiene. Preventive Medicine RZ Other systems of medicine Parasitology Public Health, Environmental and Occupational Health Infectious Diseases Food Science SDG 3 - Good Health and Well-being SDG 2 - Zero Hunger SDG 10 - Reduced Inequalities |
| title_short |
Acute Chagas disease associated with ingestion of contaminated food in Brazilian western Amazon |
| title_full |
Acute Chagas disease associated with ingestion of contaminated food in Brazilian western Amazon |
| title_fullStr |
Acute Chagas disease associated with ingestion of contaminated food in Brazilian western Amazon |
| title_full_unstemmed |
Acute Chagas disease associated with ingestion of contaminated food in Brazilian western Amazon |
| title_sort |
Acute Chagas disease associated with ingestion of contaminated food in Brazilian western Amazon |
| author |
de Sousa, Débora Raysa Teixeira |
| author_facet |
de Sousa, Débora Raysa Teixeira de Oliveira Guerra, Jorge Augusto Ortiz, Jessica Vanina do Nascimento Couceiro, Katia da Silva e Silva, Monica Regina Hosanahh Jorge Brandão, Alba Regina Guevara, Elsa Arcanjo, Ana Ruth Lima de Oliveira Júnior, Edival Ferreira Smith-Doria, Susan Mwangi, Victor Irungu Morais, Rômulo Freire Silva, George Allan Villarouco Molina, Israel Silveira, Henrique Ferreira, João Marcos Bemfica Barbosa Guerra, Maria das Graças Vale Barbosa |
| author_role |
author |
| author2 |
de Oliveira Guerra, Jorge Augusto Ortiz, Jessica Vanina do Nascimento Couceiro, Katia da Silva e Silva, Monica Regina Hosanahh Jorge Brandão, Alba Regina Guevara, Elsa Arcanjo, Ana Ruth Lima de Oliveira Júnior, Edival Ferreira Smith-Doria, Susan Mwangi, Victor Irungu Morais, Rômulo Freire Silva, George Allan Villarouco Molina, Israel Silveira, Henrique Ferreira, João Marcos Bemfica Barbosa Guerra, Maria das Graças Vale Barbosa |
| author2_role |
author author author author author author author author author author author author author author author author |
| dc.contributor.none.fl_str_mv |
Vector borne diseases and pathogens (VBD) Global Health and Tropical Medicine (GHTM) Instituto de Higiene e Medicina Tropical (IHMT) RUN |
| dc.contributor.author.fl_str_mv |
de Sousa, Débora Raysa Teixeira de Oliveira Guerra, Jorge Augusto Ortiz, Jessica Vanina do Nascimento Couceiro, Katia da Silva e Silva, Monica Regina Hosanahh Jorge Brandão, Alba Regina Guevara, Elsa Arcanjo, Ana Ruth Lima de Oliveira Júnior, Edival Ferreira Smith-Doria, Susan Mwangi, Victor Irungu Morais, Rômulo Freire Silva, George Allan Villarouco Molina, Israel Silveira, Henrique Ferreira, João Marcos Bemfica Barbosa Guerra, Maria das Graças Vale Barbosa |
| dc.subject.por.fl_str_mv |
Açaí Chagas disease outbreaks, clinical epidemiology oral transmission Trypanosoma cruzi RA0421 Public health. Hygiene. Preventive Medicine RZ Other systems of medicine Parasitology Public Health, Environmental and Occupational Health Infectious Diseases Food Science SDG 3 - Good Health and Well-being SDG 2 - Zero Hunger SDG 10 - Reduced Inequalities |
| topic |
Açaí Chagas disease outbreaks, clinical epidemiology oral transmission Trypanosoma cruzi RA0421 Public health. Hygiene. Preventive Medicine RZ Other systems of medicine Parasitology Public Health, Environmental and Occupational Health Infectious Diseases Food Science SDG 3 - Good Health and Well-being SDG 2 - Zero Hunger SDG 10 - Reduced Inequalities |
| description |
Funding Information: We would like to thank the following institutions for all the support they accorded: Fundação de Medicina Tropical Dr. Heitor Vieira Dourado, Amazonas Health Surveillance Foundation Dr. Rosimary Costa Pinto (FVS‐RCP/AM), the Municipal Health Departments of the affected by the outbreaks and Fundação de Amparo à Pesquisa do Estado do Amazonas for their financial support in acquiring materials for the molecular detection of the parasite. We would also like to thank the public health surveillance teams and the patients who agreed to participate in this study. Publisher Copyright: © 2023 Belgian Society of Tropical Medicine and the Prince Leopold Institute of Tropical Medicine. |
| publishDate |
2023 |
| dc.date.none.fl_str_mv |
2023-07-03T22:16:45Z 2023 2023-01-01T00:00:00Z |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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article |
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publishedVersion |
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http://hdl.handle.net/10362/154768 |
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http://hdl.handle.net/10362/154768 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
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1360-2276 PURE: 65014153 https://doi.org/10.1111/tmi.13899 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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10 application/pdf |
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