Plasmatic Klotho and FGF23 levels as biomarkers of CKD-associated cardiac disease in type 2 diabetic patients

Detalhes bibliográficos
Autor(a) principal: Silva, Ana Paula
Data de Publicação: 2019
Outros Autores: Mendes, Filipa, Carias, Eduarda, Baptista Gonçalves, Rui, Fragoso, André, Dias, Carolina, Tavares, Nelson, Mendonça Café, Hugo, Santos, Nélio, Rato, Fátima, Neves, Pedro Leão, Almeida, Edgar
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.1/12480
Resumo: Research over the past decade has focused on the role of Klotho as a cardio protective agent that prevents the effects of aging on the heart and reduces the burden of cardiovascular disease CVD. The role of the interaction between fibroblast growth factor 23-(FGF-23)/Klotho in Klotho-mediated actions is still under debate. The main objective was to ascertain the potential use of plasmatic Klotho and FGF23 as markers for CKD-associated cardiac disease and mortality.
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spelling Plasmatic Klotho and FGF23 levels as biomarkers of CKD-associated cardiac disease in type 2 diabetic patientsKlothoFGF-23CKDCVDLVMIResearch over the past decade has focused on the role of Klotho as a cardio protective agent that prevents the effects of aging on the heart and reduces the burden of cardiovascular disease CVD. The role of the interaction between fibroblast growth factor 23-(FGF-23)/Klotho in Klotho-mediated actions is still under debate. The main objective was to ascertain the potential use of plasmatic Klotho and FGF23 as markers for CKD-associated cardiac disease and mortality.MDPISapientiaSilva, Ana PaulaMendes, FilipaCarias, EduardaBaptista Gonçalves, RuiFragoso, AndréDias, CarolinaTavares, NelsonMendonça Café, HugoSantos, NélioRato, FátimaNeves, Pedro LeãoAlmeida, Edgar2019-05-03T14:09:14Z20192019-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.1/12480eng1422-006710.3390/ijms20071536info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-24T10:24:27Zoai:sapientia.ualg.pt:10400.1/12480Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T20:03:49.855053Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Plasmatic Klotho and FGF23 levels as biomarkers of CKD-associated cardiac disease in type 2 diabetic patients
title Plasmatic Klotho and FGF23 levels as biomarkers of CKD-associated cardiac disease in type 2 diabetic patients
spellingShingle Plasmatic Klotho and FGF23 levels as biomarkers of CKD-associated cardiac disease in type 2 diabetic patients
Silva, Ana Paula
Klotho
FGF-23
CKD
CVD
LVMI
title_short Plasmatic Klotho and FGF23 levels as biomarkers of CKD-associated cardiac disease in type 2 diabetic patients
title_full Plasmatic Klotho and FGF23 levels as biomarkers of CKD-associated cardiac disease in type 2 diabetic patients
title_fullStr Plasmatic Klotho and FGF23 levels as biomarkers of CKD-associated cardiac disease in type 2 diabetic patients
title_full_unstemmed Plasmatic Klotho and FGF23 levels as biomarkers of CKD-associated cardiac disease in type 2 diabetic patients
title_sort Plasmatic Klotho and FGF23 levels as biomarkers of CKD-associated cardiac disease in type 2 diabetic patients
author Silva, Ana Paula
author_facet Silva, Ana Paula
Mendes, Filipa
Carias, Eduarda
Baptista Gonçalves, Rui
Fragoso, André
Dias, Carolina
Tavares, Nelson
Mendonça Café, Hugo
Santos, Nélio
Rato, Fátima
Neves, Pedro Leão
Almeida, Edgar
author_role author
author2 Mendes, Filipa
Carias, Eduarda
Baptista Gonçalves, Rui
Fragoso, André
Dias, Carolina
Tavares, Nelson
Mendonça Café, Hugo
Santos, Nélio
Rato, Fátima
Neves, Pedro Leão
Almeida, Edgar
author2_role author
author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Sapientia
dc.contributor.author.fl_str_mv Silva, Ana Paula
Mendes, Filipa
Carias, Eduarda
Baptista Gonçalves, Rui
Fragoso, André
Dias, Carolina
Tavares, Nelson
Mendonça Café, Hugo
Santos, Nélio
Rato, Fátima
Neves, Pedro Leão
Almeida, Edgar
dc.subject.por.fl_str_mv Klotho
FGF-23
CKD
CVD
LVMI
topic Klotho
FGF-23
CKD
CVD
LVMI
description Research over the past decade has focused on the role of Klotho as a cardio protective agent that prevents the effects of aging on the heart and reduces the burden of cardiovascular disease CVD. The role of the interaction between fibroblast growth factor 23-(FGF-23)/Klotho in Klotho-mediated actions is still under debate. The main objective was to ascertain the potential use of plasmatic Klotho and FGF23 as markers for CKD-associated cardiac disease and mortality.
publishDate 2019
dc.date.none.fl_str_mv 2019-05-03T14:09:14Z
2019
2019-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.1/12480
url http://hdl.handle.net/10400.1/12480
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 1422-0067
10.3390/ijms20071536
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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