A literature review on pharmacologic therapy for abdominal aortic aneurysms

Detalhes bibliográficos
Autor(a) principal: Rodrigues,Marta Romão
Data de Publicação: 2023
Outros Autores: Melo,Ryan Gouveia e, Silvestre,Luís, Fernandes,Ruy Fernandes e, Martins,Carlos, Pedro,Luís Mendes
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://scielo.pt/scielo.php?script=sci_arttext&pid=S1646-706X2023000100044
Resumo: Abstract Introduction: Aortic aneurysms affect 3.3% of adults and there is a growing burden of small aneurysms detected, which may grow to need surgical repair. Still, we rely only on surgical therapy for this disease, left to monitor patients until they are candidates for treatment. Pharmacologic therapies have long been proposed and studied and still we have no evidence supporting drug therapy in small aneurysms. In this report we make a narrative review of basic molecular aspects of aneurysm disease and of evidence behind drug therapies that have been proposed and studied throughout the last decades.
id RCAP_5a5ba2f1f75a968a1a472bf666183ef4
oai_identifier_str oai:scielo:S1646-706X2023000100044
network_acronym_str RCAP
network_name_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository_id_str 7160
spelling A literature review on pharmacologic therapy for abdominal aortic aneurysmsaneurysmaortapharmacologytherapyAbstract Introduction: Aortic aneurysms affect 3.3% of adults and there is a growing burden of small aneurysms detected, which may grow to need surgical repair. Still, we rely only on surgical therapy for this disease, left to monitor patients until they are candidates for treatment. Pharmacologic therapies have long been proposed and studied and still we have no evidence supporting drug therapy in small aneurysms. In this report we make a narrative review of basic molecular aspects of aneurysm disease and of evidence behind drug therapies that have been proposed and studied throughout the last decades.Sociedade Portuguesa de Angiologia e Cirurgia Vascular2023-03-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articletext/htmlhttp://scielo.pt/scielo.php?script=sci_arttext&pid=S1646-706X2023000100044Angiologia e Cirurgia Vascular v.19 n.1 2023reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPenghttp://scielo.pt/scielo.php?script=sci_arttext&pid=S1646-706X2023000100044Rodrigues,Marta RomãoMelo,Ryan Gouveia eSilvestre,LuísFernandes,Ruy Fernandes eMartins,CarlosPedro,Luís Mendesinfo:eu-repo/semantics/openAccess2024-02-06T17:23:08Zoai:scielo:S1646-706X2023000100044Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T02:29:32.886323Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv A literature review on pharmacologic therapy for abdominal aortic aneurysms
title A literature review on pharmacologic therapy for abdominal aortic aneurysms
spellingShingle A literature review on pharmacologic therapy for abdominal aortic aneurysms
Rodrigues,Marta Romão
aneurysm
aorta
pharmacology
therapy
title_short A literature review on pharmacologic therapy for abdominal aortic aneurysms
title_full A literature review on pharmacologic therapy for abdominal aortic aneurysms
title_fullStr A literature review on pharmacologic therapy for abdominal aortic aneurysms
title_full_unstemmed A literature review on pharmacologic therapy for abdominal aortic aneurysms
title_sort A literature review on pharmacologic therapy for abdominal aortic aneurysms
author Rodrigues,Marta Romão
author_facet Rodrigues,Marta Romão
Melo,Ryan Gouveia e
Silvestre,Luís
Fernandes,Ruy Fernandes e
Martins,Carlos
Pedro,Luís Mendes
author_role author
author2 Melo,Ryan Gouveia e
Silvestre,Luís
Fernandes,Ruy Fernandes e
Martins,Carlos
Pedro,Luís Mendes
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Rodrigues,Marta Romão
Melo,Ryan Gouveia e
Silvestre,Luís
Fernandes,Ruy Fernandes e
Martins,Carlos
Pedro,Luís Mendes
dc.subject.por.fl_str_mv aneurysm
aorta
pharmacology
therapy
topic aneurysm
aorta
pharmacology
therapy
description Abstract Introduction: Aortic aneurysms affect 3.3% of adults and there is a growing burden of small aneurysms detected, which may grow to need surgical repair. Still, we rely only on surgical therapy for this disease, left to monitor patients until they are candidates for treatment. Pharmacologic therapies have long been proposed and studied and still we have no evidence supporting drug therapy in small aneurysms. In this report we make a narrative review of basic molecular aspects of aneurysm disease and of evidence behind drug therapies that have been proposed and studied throughout the last decades.
publishDate 2023
dc.date.none.fl_str_mv 2023-03-01
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://scielo.pt/scielo.php?script=sci_arttext&pid=S1646-706X2023000100044
url http://scielo.pt/scielo.php?script=sci_arttext&pid=S1646-706X2023000100044
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv http://scielo.pt/scielo.php?script=sci_arttext&pid=S1646-706X2023000100044
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Portuguesa de Angiologia e Cirurgia Vascular
publisher.none.fl_str_mv Sociedade Portuguesa de Angiologia e Cirurgia Vascular
dc.source.none.fl_str_mv Angiologia e Cirurgia Vascular v.19 n.1 2023
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
_version_ 1799137362371936256