Chronic hypoparathyroidism: review of 5 clinical cases.
Autor(a) principal: | |
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Data de Publicação: | 1991 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3328 |
Resumo: | In 5 patients with a long clinical evolution of tetany and/or convulsions and with documented hypocalcaemia and hyperphosphatemia, low or inappropriate values of parathormone were detected. Only two of the patients had a history of subtotal thyroidectomy and all presented with basal ganglia calcification, bilateral subcapsular cataracts and prolonged QTc interval in the ECG. After one month of oral therapy with calcium and calcitriol, the values of calcaemia and phosphatemia were in a near-normal range with the exception of a patient in which that normalization was much slower and only occurred after correction of magnesaemia. In this last patient statistical correlation between QTc interval in the ECG and the calcaemia was statistically significant (P less than 0.001). We conclude that the QTc interval can be a useful and accessible index in acute situations of symptomatic hypocalcaemia. |
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Chronic hypoparathyroidism: review of 5 clinical cases.Hipoparatiroidismo crónico: revisão de 5 casos clínicos.In 5 patients with a long clinical evolution of tetany and/or convulsions and with documented hypocalcaemia and hyperphosphatemia, low or inappropriate values of parathormone were detected. Only two of the patients had a history of subtotal thyroidectomy and all presented with basal ganglia calcification, bilateral subcapsular cataracts and prolonged QTc interval in the ECG. After one month of oral therapy with calcium and calcitriol, the values of calcaemia and phosphatemia were in a near-normal range with the exception of a patient in which that normalization was much slower and only occurred after correction of magnesaemia. In this last patient statistical correlation between QTc interval in the ECG and the calcaemia was statistically significant (P less than 0.001). We conclude that the QTc interval can be a useful and accessible index in acute situations of symptomatic hypocalcaemia.In 5 patients with a long clinical evolution of tetany and/or convulsions and with documented hypocalcaemia and hyperphosphatemia, low or inappropriate values of parathormone were detected. Only two of the patients had a history of subtotal thyroidectomy and all presented with basal ganglia calcification, bilateral subcapsular cataracts and prolonged QTc interval in the ECG. After one month of oral therapy with calcium and calcitriol, the values of calcaemia and phosphatemia were in a near-normal range with the exception of a patient in which that normalization was much slower and only occurred after correction of magnesaemia. In this last patient statistical correlation between QTc interval in the ECG and the calcaemia was statistically significant (P less than 0.001). We conclude that the QTc interval can be a useful and accessible index in acute situations of symptomatic hypocalcaemia.Ordem dos Médicos1991-04-30info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3328oai:ojs.www.actamedicaportuguesa.com:article/3328Acta Médica Portuguesa; Vol. 4 No. 2 (1991): Março-Abril; 83-6Acta Médica Portuguesa; Vol. 4 N.º 2 (1991): Março-Abril; 83-61646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3328https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3328/2654Anselmo, JMartins, JMatos, LBoavida, JCarreiras, FCorreia, GLima e Silva, FPereira, ECorrêa, J Cinfo:eu-repo/semantics/openAccess2022-12-20T11:02:04Zoai:ojs.www.actamedicaportuguesa.com:article/3328Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:18:18.314934Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Chronic hypoparathyroidism: review of 5 clinical cases. Hipoparatiroidismo crónico: revisão de 5 casos clínicos. |
title |
Chronic hypoparathyroidism: review of 5 clinical cases. |
spellingShingle |
Chronic hypoparathyroidism: review of 5 clinical cases. Anselmo, J |
title_short |
Chronic hypoparathyroidism: review of 5 clinical cases. |
title_full |
Chronic hypoparathyroidism: review of 5 clinical cases. |
title_fullStr |
Chronic hypoparathyroidism: review of 5 clinical cases. |
title_full_unstemmed |
Chronic hypoparathyroidism: review of 5 clinical cases. |
title_sort |
Chronic hypoparathyroidism: review of 5 clinical cases. |
author |
Anselmo, J |
author_facet |
Anselmo, J Martins, J Matos, L Boavida, J Carreiras, F Correia, G Lima e Silva, F Pereira, E Corrêa, J C |
author_role |
author |
author2 |
Martins, J Matos, L Boavida, J Carreiras, F Correia, G Lima e Silva, F Pereira, E Corrêa, J C |
author2_role |
author author author author author author author author |
dc.contributor.author.fl_str_mv |
Anselmo, J Martins, J Matos, L Boavida, J Carreiras, F Correia, G Lima e Silva, F Pereira, E Corrêa, J C |
description |
In 5 patients with a long clinical evolution of tetany and/or convulsions and with documented hypocalcaemia and hyperphosphatemia, low or inappropriate values of parathormone were detected. Only two of the patients had a history of subtotal thyroidectomy and all presented with basal ganglia calcification, bilateral subcapsular cataracts and prolonged QTc interval in the ECG. After one month of oral therapy with calcium and calcitriol, the values of calcaemia and phosphatemia were in a near-normal range with the exception of a patient in which that normalization was much slower and only occurred after correction of magnesaemia. In this last patient statistical correlation between QTc interval in the ECG and the calcaemia was statistically significant (P less than 0.001). We conclude that the QTc interval can be a useful and accessible index in acute situations of symptomatic hypocalcaemia. |
publishDate |
1991 |
dc.date.none.fl_str_mv |
1991-04-30 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3328 oai:ojs.www.actamedicaportuguesa.com:article/3328 |
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https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3328 |
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oai:ojs.www.actamedicaportuguesa.com:article/3328 |
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por |
language |
por |
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https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3328 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3328/2654 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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application/pdf |
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Ordem dos Médicos |
publisher.none.fl_str_mv |
Ordem dos Médicos |
dc.source.none.fl_str_mv |
Acta Médica Portuguesa; Vol. 4 No. 2 (1991): Março-Abril; 83-6 Acta Médica Portuguesa; Vol. 4 N.º 2 (1991): Março-Abril; 83-6 1646-0758 0870-399X reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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