Red seaweed-derived compounds as a potential new approach for acne vulgaris care

Detalhes bibliográficos
Autor(a) principal: Januário, Adriana P.
Data de Publicação: 2021
Outros Autores: Félix, Rafael, Félix, Carina, Reboleira, João, Valentão, Patrícia, Lemos, Marco F.L.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.8/7542
Resumo: Funding: This study had the support of the Fundação para a Ciência e a Tecnologia (FCT) Strategic Projects UID/MAR/04292/2020 and UIDB/50006/2020 granted to MARE and REQUIMTE, respectively; the grant awarded to A.P.J. (2020.08202.BD); and project MARINE INVADERS (POCI-01-0145-FEDER-031144). The authors also wish to acknowledge the support of the European Union through EASME Blue Labs project AMALIA, Algae-to-MArket Lab IdeAs (EASME/EMFF/2016/1.2.1.4/03/SI2.750419). The project was also partially funded by RDandT co-promotion project ORCHESTRA (POCI-01-0247-FEDER-070155) through COMPETE, Portugal 2020 and FCT, and COSMOS (MAR-04.03.01-FEAMP-0370) through GAL PESCA OESTE and MAR2020 in the framework of PORTUGAL2020 and the European Maritime and Fisheries Fund.
id RCAP_5c73096a47298841b2f4db4e2ae19e1a
oai_identifier_str oai:iconline.ipleiria.pt:10400.8/7542
network_acronym_str RCAP
network_name_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository_id_str 7160
spelling Red seaweed-derived compounds as a potential new approach for acne vulgaris careAcne pathophysiologyAntibacterialBioactive compoundsCutibacterium acnesInflammationRhodophytaSeaweed extractsFunding: This study had the support of the Fundação para a Ciência e a Tecnologia (FCT) Strategic Projects UID/MAR/04292/2020 and UIDB/50006/2020 granted to MARE and REQUIMTE, respectively; the grant awarded to A.P.J. (2020.08202.BD); and project MARINE INVADERS (POCI-01-0145-FEDER-031144). The authors also wish to acknowledge the support of the European Union through EASME Blue Labs project AMALIA, Algae-to-MArket Lab IdeAs (EASME/EMFF/2016/1.2.1.4/03/SI2.750419). The project was also partially funded by RDandT co-promotion project ORCHESTRA (POCI-01-0247-FEDER-070155) through COMPETE, Portugal 2020 and FCT, and COSMOS (MAR-04.03.01-FEAMP-0370) through GAL PESCA OESTE and MAR2020 in the framework of PORTUGAL2020 and the European Maritime and Fisheries Fund.Acne vulgaris (AV) is a chronic skin disease of the pilosebaceous unit affecting both adolescents and adults. Its pathophysiology includes processes of inflammation, increased keratinization, sebum production, hormonal dysregulation, and bacterial Cutibacterium acnes proliferation. Common AV has been treated with antibiotics since the 1960s, but strain resistance has emerged and is of paramount concern. Macroalgae are known producers of substances with bioactive properties, including anti-viral, antibacterial, antioxidant, and anti-inflammatory properties, among several others. In particular, red algae are rich in bioactive compounds such as polysaccharides, phenolic compounds, lipids, sterols, alkaloids, and terpenoids, conferring them antioxidant, antimicrobial, and anti-inflammatory activities, among others. Thus, the exploration of compounds from marine resources can be an appealing approach to discover new treatment options against AV. The aim of this work is to provide an overview of the current knowledge of the potentialities of red macroalgae in the treatment of AV by reviewing the main therapeutic targets of this disease, and then the existence of compounds or extracts with bioactive properties against them.MDPIIC-OnlineJanuário, Adriana P.Félix, RafaelFélix, CarinaReboleira, JoãoValentão, PatríciaLemos, Marco F.L.2022-08-17T08:02:01Z20212021-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.8/7542engJanuário, A.P.; Félix, R.; Félix, C.; Reboleira, J.; Valentão, P.; Lemos, M.F.L. Red Seaweed-Derived Compounds as a Potential New Approach for Acne Vulgaris Care. Pharmaceutics 2021, 13, 1930. https://doi.org/10.3390/pharmaceutics131119301999-492310.3390/pharmaceutics13111930info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-01-17T15:55:24Zoai:iconline.ipleiria.pt:10400.8/7542Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T01:50:28.692768Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Red seaweed-derived compounds as a potential new approach for acne vulgaris care
title Red seaweed-derived compounds as a potential new approach for acne vulgaris care
spellingShingle Red seaweed-derived compounds as a potential new approach for acne vulgaris care
Januário, Adriana P.
Acne pathophysiology
Antibacterial
Bioactive compounds
Cutibacterium acnes
Inflammation
Rhodophyta
Seaweed extracts
title_short Red seaweed-derived compounds as a potential new approach for acne vulgaris care
title_full Red seaweed-derived compounds as a potential new approach for acne vulgaris care
title_fullStr Red seaweed-derived compounds as a potential new approach for acne vulgaris care
title_full_unstemmed Red seaweed-derived compounds as a potential new approach for acne vulgaris care
title_sort Red seaweed-derived compounds as a potential new approach for acne vulgaris care
author Januário, Adriana P.
author_facet Januário, Adriana P.
Félix, Rafael
Félix, Carina
Reboleira, João
Valentão, Patrícia
Lemos, Marco F.L.
author_role author
author2 Félix, Rafael
Félix, Carina
Reboleira, João
Valentão, Patrícia
Lemos, Marco F.L.
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv IC-Online
dc.contributor.author.fl_str_mv Januário, Adriana P.
Félix, Rafael
Félix, Carina
Reboleira, João
Valentão, Patrícia
Lemos, Marco F.L.
dc.subject.por.fl_str_mv Acne pathophysiology
Antibacterial
Bioactive compounds
Cutibacterium acnes
Inflammation
Rhodophyta
Seaweed extracts
topic Acne pathophysiology
Antibacterial
Bioactive compounds
Cutibacterium acnes
Inflammation
Rhodophyta
Seaweed extracts
description Funding: This study had the support of the Fundação para a Ciência e a Tecnologia (FCT) Strategic Projects UID/MAR/04292/2020 and UIDB/50006/2020 granted to MARE and REQUIMTE, respectively; the grant awarded to A.P.J. (2020.08202.BD); and project MARINE INVADERS (POCI-01-0145-FEDER-031144). The authors also wish to acknowledge the support of the European Union through EASME Blue Labs project AMALIA, Algae-to-MArket Lab IdeAs (EASME/EMFF/2016/1.2.1.4/03/SI2.750419). The project was also partially funded by RDandT co-promotion project ORCHESTRA (POCI-01-0247-FEDER-070155) through COMPETE, Portugal 2020 and FCT, and COSMOS (MAR-04.03.01-FEAMP-0370) through GAL PESCA OESTE and MAR2020 in the framework of PORTUGAL2020 and the European Maritime and Fisheries Fund.
publishDate 2021
dc.date.none.fl_str_mv 2021
2021-01-01T00:00:00Z
2022-08-17T08:02:01Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.8/7542
url http://hdl.handle.net/10400.8/7542
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Januário, A.P.; Félix, R.; Félix, C.; Reboleira, J.; Valentão, P.; Lemos, M.F.L. Red Seaweed-Derived Compounds as a Potential New Approach for Acne Vulgaris Care. Pharmaceutics 2021, 13, 1930. https://doi.org/10.3390/pharmaceutics13111930
1999-4923
10.3390/pharmaceutics13111930
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
_version_ 1799136997075320832

Registros relacionados