Late-onset neonatal sepsis caused by group A Streptococcus - an unlikely agent

Detalhes bibliográficos
Autor(a) principal: Ventura, Ana
Data de Publicação: 2019
Outros Autores: Rúbio, Catarina, Rodrigues, Diogo, Silva, Inês, Peres, Ana, Cunha, Florbela
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://doi.org/10.25753/BirthGrowthMJ.v28.i1.14558
Resumo: Neonatal sepsis due to group A Streptococcus is rare and has a high associated mortality. The case of a 14-day-old female neonate who presented to the Emergency Department with feed refusal and hyporeactivity is reported. The girl was born at 36 weeks of gestation and had an unremarkable pregnancy and birth. Peripheral white blood cell count was 18.100/mm3 with 81% neutrophils, and C-reactive protein was 13.6 mg/dL. Urinalysis, cerebrospinal fluid cytochemical examination, and chest X-ray were normal. A multisensitive group A Streptococcus was isolated in the blood culture and ten-day course of ampicillin was completed. Urine and cerebrospinal fluid cultures were negative. All co-inhabitants were tested for the presence of group A Streptococcus antigen in the oropharynx, which was positive in a two-year-old cousin. Group A Streptococcus is an uncommon neonatal sepsis agent. Transmission in the community through a carrier should be considered. This case highlights the importance of infection preventive measures for the newborn at home.
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spelling Late-onset neonatal sepsis caused by group A Streptococcus - an unlikely agentSépsis neonatal tardia a Streptococcus do grupo A - um agente improvávelCase ReportsNeonatal sepsis due to group A Streptococcus is rare and has a high associated mortality. The case of a 14-day-old female neonate who presented to the Emergency Department with feed refusal and hyporeactivity is reported. The girl was born at 36 weeks of gestation and had an unremarkable pregnancy and birth. Peripheral white blood cell count was 18.100/mm3 with 81% neutrophils, and C-reactive protein was 13.6 mg/dL. Urinalysis, cerebrospinal fluid cytochemical examination, and chest X-ray were normal. A multisensitive group A Streptococcus was isolated in the blood culture and ten-day course of ampicillin was completed. Urine and cerebrospinal fluid cultures were negative. All co-inhabitants were tested for the presence of group A Streptococcus antigen in the oropharynx, which was positive in a two-year-old cousin. Group A Streptococcus is an uncommon neonatal sepsis agent. Transmission in the community through a carrier should be considered. This case highlights the importance of infection preventive measures for the newborn at home.Sépsis neonatal tardia por Streptococcus do grupo A é uma entidade rara, com mortalidade elevada. É descrito o caso de um recém-nascido do sexo feminino, com 14 dias de vida, que recorreu ao Serviço de Urgência por recusa alimentar e hiporreatividade. Este tinha nascido às 36 semanas de gestação, tendo a gravidez, parto e período neonatal decorrido sem intercorrências. Entre os exames realizados destacamse a contagem leucocitária de 18.100/mm3 com 81% de neutrófilos, proteína C-reativa de 13.6 mg/dL, e exame sumário de urina, exame citoquímico do líquor e radiografia torácica sem alterações. Por isolamento de Streptococcus do grupo A na hemocultura, o recém-nascido cumpriu dez dias de ampicilina. A cultura do líquor e urocultura foram negativas. Foi pesquisada a presença de antigénio de Streptococcus do grupo A na orofaringe em todos os conviventes, sendo positiva numa prima com dois anos. O Streptococcus do grupo A raramente é descrito como agente de sépsis neonatal e a sua transmissão na comunidade através de um portador deve ser considerada. Com este caso, pretende reforçar-se a importância das medidas de prevenção da infeção nos cuidados de puericultura no domicílio.Centro Hospitalar Universitário do Porto2019-04-11T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttps://doi.org/10.25753/BirthGrowthMJ.v28.i1.14558eng2183-9417Ventura, AnaRúbio, CatarinaRodrigues, DiogoSilva, InêsPeres, AnaCunha, Florbelainfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-09-21T14:55:30Zoai:ojs.revistas.rcaap.pt:article/14558Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T15:56:26.911196Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Late-onset neonatal sepsis caused by group A Streptococcus - an unlikely agent
Sépsis neonatal tardia a Streptococcus do grupo A - um agente improvável
title Late-onset neonatal sepsis caused by group A Streptococcus - an unlikely agent
spellingShingle Late-onset neonatal sepsis caused by group A Streptococcus - an unlikely agent
Ventura, Ana
Case Reports
title_short Late-onset neonatal sepsis caused by group A Streptococcus - an unlikely agent
title_full Late-onset neonatal sepsis caused by group A Streptococcus - an unlikely agent
title_fullStr Late-onset neonatal sepsis caused by group A Streptococcus - an unlikely agent
title_full_unstemmed Late-onset neonatal sepsis caused by group A Streptococcus - an unlikely agent
title_sort Late-onset neonatal sepsis caused by group A Streptococcus - an unlikely agent
author Ventura, Ana
author_facet Ventura, Ana
Rúbio, Catarina
Rodrigues, Diogo
Silva, Inês
Peres, Ana
Cunha, Florbela
author_role author
author2 Rúbio, Catarina
Rodrigues, Diogo
Silva, Inês
Peres, Ana
Cunha, Florbela
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Ventura, Ana
Rúbio, Catarina
Rodrigues, Diogo
Silva, Inês
Peres, Ana
Cunha, Florbela
dc.subject.por.fl_str_mv Case Reports
topic Case Reports
description Neonatal sepsis due to group A Streptococcus is rare and has a high associated mortality. The case of a 14-day-old female neonate who presented to the Emergency Department with feed refusal and hyporeactivity is reported. The girl was born at 36 weeks of gestation and had an unremarkable pregnancy and birth. Peripheral white blood cell count was 18.100/mm3 with 81% neutrophils, and C-reactive protein was 13.6 mg/dL. Urinalysis, cerebrospinal fluid cytochemical examination, and chest X-ray were normal. A multisensitive group A Streptococcus was isolated in the blood culture and ten-day course of ampicillin was completed. Urine and cerebrospinal fluid cultures were negative. All co-inhabitants were tested for the presence of group A Streptococcus antigen in the oropharynx, which was positive in a two-year-old cousin. Group A Streptococcus is an uncommon neonatal sepsis agent. Transmission in the community through a carrier should be considered. This case highlights the importance of infection preventive measures for the newborn at home.
publishDate 2019
dc.date.none.fl_str_mv 2019-04-11T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.uri.fl_str_mv https://doi.org/10.25753/BirthGrowthMJ.v28.i1.14558
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dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 2183-9417
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dc.publisher.none.fl_str_mv Centro Hospitalar Universitário do Porto
publisher.none.fl_str_mv Centro Hospitalar Universitário do Porto
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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