Nanoparticle exposure and hazard in the ceramic industry: an overview of potential sources, toxicity and health effects

Detalhes bibliográficos
Autor(a) principal: Bessa, Maria João
Data de Publicação: 2020
Outros Autores: Brandão, Fátima, Viana, Mar, Gomes, João F., Monfort, Eliseo, Cassee, Flemming R., Fraga, Sónia, Teixeira, João Paulo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.18/6542
Resumo: The ceramic industry is an industrial sector of great impact in the global economy that has been benefiting from advances in materials and processing technologies. Ceramic manufacturing has a strong potential for airborne particle formation and emission, namely of ultrafine particles (UFP) and nanoparticles (NP), meaning that workers of those industries are at risk of potential exposure to these particles. At present, little is known on the impact of engineered nanoparticles (ENP) on the environment and human health and no established Occupational Exposure Limits (OEL) or specific regulations to airborne nanoparticles (ANP) exposure exist raising concerns about the possible consequences of such exposure. In this paper, we provide an overview of the current knowledge on occupational exposure to NP in the ceramic industry and their impact on human health. Possible sources and exposure scenarios, a summary of the existing methods for evaluation and monitoring of ANP in the workplace environment and proposed Nano Reference Values (NRV) for different classes of NP are presented. Case studies on occupational exposure to ANP generated at different stages of the ceramic manufacturing process are described. Finally, the toxicological potential of intentional and unintentional ANP that have been identified in the ceramic industry workplace environment is discussed based on the existing evidence from in vitro and in vivo inhalation toxicity studies.
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spelling Nanoparticle exposure and hazard in the ceramic industry: an overview of potential sources, toxicity and health effectsAirborne NanoparticlesCeramic IndustryHuman HealthOccupational ExposureToxicityGenotoxicidade AmbientalThe ceramic industry is an industrial sector of great impact in the global economy that has been benefiting from advances in materials and processing technologies. Ceramic manufacturing has a strong potential for airborne particle formation and emission, namely of ultrafine particles (UFP) and nanoparticles (NP), meaning that workers of those industries are at risk of potential exposure to these particles. At present, little is known on the impact of engineered nanoparticles (ENP) on the environment and human health and no established Occupational Exposure Limits (OEL) or specific regulations to airborne nanoparticles (ANP) exposure exist raising concerns about the possible consequences of such exposure. In this paper, we provide an overview of the current knowledge on occupational exposure to NP in the ceramic industry and their impact on human health. Possible sources and exposure scenarios, a summary of the existing methods for evaluation and monitoring of ANP in the workplace environment and proposed Nano Reference Values (NRV) for different classes of NP are presented. Case studies on occupational exposure to ANP generated at different stages of the ceramic manufacturing process are described. Finally, the toxicological potential of intentional and unintentional ANP that have been identified in the ceramic industry workplace environment is discussed based on the existing evidence from in vitro and in vivo inhalation toxicity studies.This work was supported by the Portuguese Foundation for Science and Technology (FCT) through the ERA-NET SIINN project CERASAFE (SIINN/0004/2014). M.J. Bessa and F. Brandão are recipients of FCT PhD scholarships (SFRH/BD/120646/2016 and SFRH/BD/101060/2014) under the framework of Programa Operacional Capital Humano (POCH) and European Union fundingElsevier/ Academic PressRepositório Científico do Instituto Nacional de SaúdeBessa, Maria JoãoBrandão, FátimaViana, MarGomes, João F.Monfort, EliseoCassee, Flemming R.Fraga, SóniaTeixeira, João Paulo2020-04-28T20:42:58Z2020-052020-05-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.18/6542engEnviron Res. 2020 May;184:109297. doi: 10.1016/j.envres.2020.109297. Epub 2020 Feb 240013-935110.1016/j.envres.2020.109297info:eu-repo/semantics/embargoedAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-20T15:41:42Zoai:repositorio.insa.pt:10400.18/6542Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:41:33.589054Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Nanoparticle exposure and hazard in the ceramic industry: an overview of potential sources, toxicity and health effects
title Nanoparticle exposure and hazard in the ceramic industry: an overview of potential sources, toxicity and health effects
spellingShingle Nanoparticle exposure and hazard in the ceramic industry: an overview of potential sources, toxicity and health effects
Bessa, Maria João
Airborne Nanoparticles
Ceramic Industry
Human Health
Occupational Exposure
Toxicity
Genotoxicidade Ambiental
title_short Nanoparticle exposure and hazard in the ceramic industry: an overview of potential sources, toxicity and health effects
title_full Nanoparticle exposure and hazard in the ceramic industry: an overview of potential sources, toxicity and health effects
title_fullStr Nanoparticle exposure and hazard in the ceramic industry: an overview of potential sources, toxicity and health effects
title_full_unstemmed Nanoparticle exposure and hazard in the ceramic industry: an overview of potential sources, toxicity and health effects
title_sort Nanoparticle exposure and hazard in the ceramic industry: an overview of potential sources, toxicity and health effects
author Bessa, Maria João
author_facet Bessa, Maria João
Brandão, Fátima
Viana, Mar
Gomes, João F.
Monfort, Eliseo
Cassee, Flemming R.
Fraga, Sónia
Teixeira, João Paulo
author_role author
author2 Brandão, Fátima
Viana, Mar
Gomes, João F.
Monfort, Eliseo
Cassee, Flemming R.
Fraga, Sónia
Teixeira, João Paulo
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório Científico do Instituto Nacional de Saúde
dc.contributor.author.fl_str_mv Bessa, Maria João
Brandão, Fátima
Viana, Mar
Gomes, João F.
Monfort, Eliseo
Cassee, Flemming R.
Fraga, Sónia
Teixeira, João Paulo
dc.subject.por.fl_str_mv Airborne Nanoparticles
Ceramic Industry
Human Health
Occupational Exposure
Toxicity
Genotoxicidade Ambiental
topic Airborne Nanoparticles
Ceramic Industry
Human Health
Occupational Exposure
Toxicity
Genotoxicidade Ambiental
description The ceramic industry is an industrial sector of great impact in the global economy that has been benefiting from advances in materials and processing technologies. Ceramic manufacturing has a strong potential for airborne particle formation and emission, namely of ultrafine particles (UFP) and nanoparticles (NP), meaning that workers of those industries are at risk of potential exposure to these particles. At present, little is known on the impact of engineered nanoparticles (ENP) on the environment and human health and no established Occupational Exposure Limits (OEL) or specific regulations to airborne nanoparticles (ANP) exposure exist raising concerns about the possible consequences of such exposure. In this paper, we provide an overview of the current knowledge on occupational exposure to NP in the ceramic industry and their impact on human health. Possible sources and exposure scenarios, a summary of the existing methods for evaluation and monitoring of ANP in the workplace environment and proposed Nano Reference Values (NRV) for different classes of NP are presented. Case studies on occupational exposure to ANP generated at different stages of the ceramic manufacturing process are described. Finally, the toxicological potential of intentional and unintentional ANP that have been identified in the ceramic industry workplace environment is discussed based on the existing evidence from in vitro and in vivo inhalation toxicity studies.
publishDate 2020
dc.date.none.fl_str_mv 2020-04-28T20:42:58Z
2020-05
2020-05-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.18/6542
url http://hdl.handle.net/10400.18/6542
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Environ Res. 2020 May;184:109297. doi: 10.1016/j.envres.2020.109297. Epub 2020 Feb 24
0013-9351
10.1016/j.envres.2020.109297
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dc.publisher.none.fl_str_mv Elsevier/ Academic Press
publisher.none.fl_str_mv Elsevier/ Academic Press
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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