Nanoparticle exposure and hazard in the ceramic industry: an overview of potential sources, toxicity and health effects
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.18/6542 |
Resumo: | The ceramic industry is an industrial sector of great impact in the global economy that has been benefiting from advances in materials and processing technologies. Ceramic manufacturing has a strong potential for airborne particle formation and emission, namely of ultrafine particles (UFP) and nanoparticles (NP), meaning that workers of those industries are at risk of potential exposure to these particles. At present, little is known on the impact of engineered nanoparticles (ENP) on the environment and human health and no established Occupational Exposure Limits (OEL) or specific regulations to airborne nanoparticles (ANP) exposure exist raising concerns about the possible consequences of such exposure. In this paper, we provide an overview of the current knowledge on occupational exposure to NP in the ceramic industry and their impact on human health. Possible sources and exposure scenarios, a summary of the existing methods for evaluation and monitoring of ANP in the workplace environment and proposed Nano Reference Values (NRV) for different classes of NP are presented. Case studies on occupational exposure to ANP generated at different stages of the ceramic manufacturing process are described. Finally, the toxicological potential of intentional and unintentional ANP that have been identified in the ceramic industry workplace environment is discussed based on the existing evidence from in vitro and in vivo inhalation toxicity studies. |
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Nanoparticle exposure and hazard in the ceramic industry: an overview of potential sources, toxicity and health effectsAirborne NanoparticlesCeramic IndustryHuman HealthOccupational ExposureToxicityGenotoxicidade AmbientalThe ceramic industry is an industrial sector of great impact in the global economy that has been benefiting from advances in materials and processing technologies. Ceramic manufacturing has a strong potential for airborne particle formation and emission, namely of ultrafine particles (UFP) and nanoparticles (NP), meaning that workers of those industries are at risk of potential exposure to these particles. At present, little is known on the impact of engineered nanoparticles (ENP) on the environment and human health and no established Occupational Exposure Limits (OEL) or specific regulations to airborne nanoparticles (ANP) exposure exist raising concerns about the possible consequences of such exposure. In this paper, we provide an overview of the current knowledge on occupational exposure to NP in the ceramic industry and their impact on human health. Possible sources and exposure scenarios, a summary of the existing methods for evaluation and monitoring of ANP in the workplace environment and proposed Nano Reference Values (NRV) for different classes of NP are presented. Case studies on occupational exposure to ANP generated at different stages of the ceramic manufacturing process are described. Finally, the toxicological potential of intentional and unintentional ANP that have been identified in the ceramic industry workplace environment is discussed based on the existing evidence from in vitro and in vivo inhalation toxicity studies.This work was supported by the Portuguese Foundation for Science and Technology (FCT) through the ERA-NET SIINN project CERASAFE (SIINN/0004/2014). M.J. Bessa and F. Brandão are recipients of FCT PhD scholarships (SFRH/BD/120646/2016 and SFRH/BD/101060/2014) under the framework of Programa Operacional Capital Humano (POCH) and European Union fundingElsevier/ Academic PressRepositório Científico do Instituto Nacional de SaúdeBessa, Maria JoãoBrandão, FátimaViana, MarGomes, João F.Monfort, EliseoCassee, Flemming R.Fraga, SóniaTeixeira, João Paulo2020-04-28T20:42:58Z2020-052020-05-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.18/6542engEnviron Res. 2020 May;184:109297. doi: 10.1016/j.envres.2020.109297. Epub 2020 Feb 240013-935110.1016/j.envres.2020.109297info:eu-repo/semantics/embargoedAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-20T15:41:42Zoai:repositorio.insa.pt:10400.18/6542Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:41:33.589054Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Nanoparticle exposure and hazard in the ceramic industry: an overview of potential sources, toxicity and health effects |
title |
Nanoparticle exposure and hazard in the ceramic industry: an overview of potential sources, toxicity and health effects |
spellingShingle |
Nanoparticle exposure and hazard in the ceramic industry: an overview of potential sources, toxicity and health effects Bessa, Maria João Airborne Nanoparticles Ceramic Industry Human Health Occupational Exposure Toxicity Genotoxicidade Ambiental |
title_short |
Nanoparticle exposure and hazard in the ceramic industry: an overview of potential sources, toxicity and health effects |
title_full |
Nanoparticle exposure and hazard in the ceramic industry: an overview of potential sources, toxicity and health effects |
title_fullStr |
Nanoparticle exposure and hazard in the ceramic industry: an overview of potential sources, toxicity and health effects |
title_full_unstemmed |
Nanoparticle exposure and hazard in the ceramic industry: an overview of potential sources, toxicity and health effects |
title_sort |
Nanoparticle exposure and hazard in the ceramic industry: an overview of potential sources, toxicity and health effects |
author |
Bessa, Maria João |
author_facet |
Bessa, Maria João Brandão, Fátima Viana, Mar Gomes, João F. Monfort, Eliseo Cassee, Flemming R. Fraga, Sónia Teixeira, João Paulo |
author_role |
author |
author2 |
Brandão, Fátima Viana, Mar Gomes, João F. Monfort, Eliseo Cassee, Flemming R. Fraga, Sónia Teixeira, João Paulo |
author2_role |
author author author author author author author |
dc.contributor.none.fl_str_mv |
Repositório Científico do Instituto Nacional de Saúde |
dc.contributor.author.fl_str_mv |
Bessa, Maria João Brandão, Fátima Viana, Mar Gomes, João F. Monfort, Eliseo Cassee, Flemming R. Fraga, Sónia Teixeira, João Paulo |
dc.subject.por.fl_str_mv |
Airborne Nanoparticles Ceramic Industry Human Health Occupational Exposure Toxicity Genotoxicidade Ambiental |
topic |
Airborne Nanoparticles Ceramic Industry Human Health Occupational Exposure Toxicity Genotoxicidade Ambiental |
description |
The ceramic industry is an industrial sector of great impact in the global economy that has been benefiting from advances in materials and processing technologies. Ceramic manufacturing has a strong potential for airborne particle formation and emission, namely of ultrafine particles (UFP) and nanoparticles (NP), meaning that workers of those industries are at risk of potential exposure to these particles. At present, little is known on the impact of engineered nanoparticles (ENP) on the environment and human health and no established Occupational Exposure Limits (OEL) or specific regulations to airborne nanoparticles (ANP) exposure exist raising concerns about the possible consequences of such exposure. In this paper, we provide an overview of the current knowledge on occupational exposure to NP in the ceramic industry and their impact on human health. Possible sources and exposure scenarios, a summary of the existing methods for evaluation and monitoring of ANP in the workplace environment and proposed Nano Reference Values (NRV) for different classes of NP are presented. Case studies on occupational exposure to ANP generated at different stages of the ceramic manufacturing process are described. Finally, the toxicological potential of intentional and unintentional ANP that have been identified in the ceramic industry workplace environment is discussed based on the existing evidence from in vitro and in vivo inhalation toxicity studies. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-04-28T20:42:58Z 2020-05 2020-05-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.18/6542 |
url |
http://hdl.handle.net/10400.18/6542 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Environ Res. 2020 May;184:109297. doi: 10.1016/j.envres.2020.109297. Epub 2020 Feb 24 0013-9351 10.1016/j.envres.2020.109297 |
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info:eu-repo/semantics/embargoedAccess |
eu_rights_str_mv |
embargoedAccess |
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application/pdf |
dc.publisher.none.fl_str_mv |
Elsevier/ Academic Press |
publisher.none.fl_str_mv |
Elsevier/ Academic Press |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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