HIV and tuberculosis co-infection among migrants in Europe: A systematic review on the prevalence, incidence and mortality

Detalhes bibliográficos
Autor(a) principal: Tavares, Ana Maria
Data de Publicação: 2017
Outros Autores: Fronteira, Ines, Couto, Isabel, Machado, Diana, Viveiros, Miguel, Abecasis, Ana B., Dias, Sonia
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/36492
Resumo: BACKGROUND: International human migration has been rapidly growing. Migrants coming from low and middle income countries continue to be considerably vulnerable and at higher risk for infectious diseases, namely HIV (Human Immunodeficiency Virus) and tuberculosis (TB). In Europe, the number of patients with HIV-TB co-infection has been increasing and migration could be one of the potential driving forces. OBJECTIVE: This systematic review aims to improve the understanding on the burden of HIV-TB co-infection among migrants in Europe and to assess whether these populations are particularly vulnerable to this co-infection compared to nationals. DESIGN: MEDLINE®, Web of Science® and Scopus® databases were searched from March to April 2016 using combinations of keywords. Titles and abstracts were screened and studies meeting the inclusion criteria proceeded for full-text revision. These articles were then selected for data extraction on the prevalence, incidence and mortality. RESULTS: The majority of HIV-TB prevalence data reported in the analysed studies, including extrapulmonary/disseminated TB forms, was higher among migrant vs. nationals, some of the studies even showing increasing trends over time. Additionally, while HIV-TB incidence rates have decreased among migrants and nationals, migrants are still at a higher risk for this co-infection. Migrants with HIV-TB co-infection were also more prone to unsuccessful treatment outcomes, death and drug resistant TB. However, contradicting results also showed lower mortality compared to nationals. CONCLUSIONS: Overall, a disproportionate vulnerability of migrants to acquire the HIV-TB co-infection was observed across studies. Such vulnerability has been associated to low socioeconomic status, poor living conditions and limited access to healthcare. Adequate social support, early detection, appropriate treatment, and adequate access to healthcare are key improvements to tackle HIV-TB co-infection among these populations.
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spelling HIV and tuberculosis co-infection among migrants in Europe: A systematic review on the prevalence, incidence and mortalityINFECTIOUS-DISEASESANTIRETROVIRAL THERAPYRISK-FACTORSIMMIGRANTSEPIDEMIOLOGYIMPACTAREAPOPULATIONSMIGRATIONCOUNTRIESInfectious DiseasesEpidemiologySDG 3 - Good Health and Well-beingBACKGROUND: International human migration has been rapidly growing. Migrants coming from low and middle income countries continue to be considerably vulnerable and at higher risk for infectious diseases, namely HIV (Human Immunodeficiency Virus) and tuberculosis (TB). In Europe, the number of patients with HIV-TB co-infection has been increasing and migration could be one of the potential driving forces. OBJECTIVE: This systematic review aims to improve the understanding on the burden of HIV-TB co-infection among migrants in Europe and to assess whether these populations are particularly vulnerable to this co-infection compared to nationals. DESIGN: MEDLINE®, Web of Science® and Scopus® databases were searched from March to April 2016 using combinations of keywords. Titles and abstracts were screened and studies meeting the inclusion criteria proceeded for full-text revision. These articles were then selected for data extraction on the prevalence, incidence and mortality. RESULTS: The majority of HIV-TB prevalence data reported in the analysed studies, including extrapulmonary/disseminated TB forms, was higher among migrant vs. nationals, some of the studies even showing increasing trends over time. Additionally, while HIV-TB incidence rates have decreased among migrants and nationals, migrants are still at a higher risk for this co-infection. Migrants with HIV-TB co-infection were also more prone to unsuccessful treatment outcomes, death and drug resistant TB. However, contradicting results also showed lower mortality compared to nationals. CONCLUSIONS: Overall, a disproportionate vulnerability of migrants to acquire the HIV-TB co-infection was observed across studies. Such vulnerability has been associated to low socioeconomic status, poor living conditions and limited access to healthcare. Adequate social support, early detection, appropriate treatment, and adequate access to healthcare are key improvements to tackle HIV-TB co-infection among these populations.Instituto de Higiene e Medicina Tropical (IHMT)Global Health and Tropical Medicine (GHTM)Population health, policies and services (PPS)TB, HIV and opportunistic diseases and pathogens (THOP)RUNTavares, Ana MariaFronteira, InesCouto, IsabelMachado, DianaViveiros, MiguelAbecasis, Ana B.Dias, Sonia2018-05-10T22:18:15Z2017-09-282017-09-28T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article16application/pdfhttp://hdl.handle.net/10362/36492eng1932-6203PURE: 3256045https://doi.org/10.1371/journal.pone.0185526info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T04:19:54Zoai:run.unl.pt:10362/36492Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:30:31.262868Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv HIV and tuberculosis co-infection among migrants in Europe: A systematic review on the prevalence, incidence and mortality
title HIV and tuberculosis co-infection among migrants in Europe: A systematic review on the prevalence, incidence and mortality
spellingShingle HIV and tuberculosis co-infection among migrants in Europe: A systematic review on the prevalence, incidence and mortality
Tavares, Ana Maria
INFECTIOUS-DISEASES
ANTIRETROVIRAL THERAPY
RISK-FACTORS
IMMIGRANTS
EPIDEMIOLOGY
IMPACT
AREA
POPULATIONS
MIGRATION
COUNTRIES
Infectious Diseases
Epidemiology
SDG 3 - Good Health and Well-being
title_short HIV and tuberculosis co-infection among migrants in Europe: A systematic review on the prevalence, incidence and mortality
title_full HIV and tuberculosis co-infection among migrants in Europe: A systematic review on the prevalence, incidence and mortality
title_fullStr HIV and tuberculosis co-infection among migrants in Europe: A systematic review on the prevalence, incidence and mortality
title_full_unstemmed HIV and tuberculosis co-infection among migrants in Europe: A systematic review on the prevalence, incidence and mortality
title_sort HIV and tuberculosis co-infection among migrants in Europe: A systematic review on the prevalence, incidence and mortality
author Tavares, Ana Maria
author_facet Tavares, Ana Maria
Fronteira, Ines
Couto, Isabel
Machado, Diana
Viveiros, Miguel
Abecasis, Ana B.
Dias, Sonia
author_role author
author2 Fronteira, Ines
Couto, Isabel
Machado, Diana
Viveiros, Miguel
Abecasis, Ana B.
Dias, Sonia
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Instituto de Higiene e Medicina Tropical (IHMT)
Global Health and Tropical Medicine (GHTM)
Population health, policies and services (PPS)
TB, HIV and opportunistic diseases and pathogens (THOP)
RUN
dc.contributor.author.fl_str_mv Tavares, Ana Maria
Fronteira, Ines
Couto, Isabel
Machado, Diana
Viveiros, Miguel
Abecasis, Ana B.
Dias, Sonia
dc.subject.por.fl_str_mv INFECTIOUS-DISEASES
ANTIRETROVIRAL THERAPY
RISK-FACTORS
IMMIGRANTS
EPIDEMIOLOGY
IMPACT
AREA
POPULATIONS
MIGRATION
COUNTRIES
Infectious Diseases
Epidemiology
SDG 3 - Good Health and Well-being
topic INFECTIOUS-DISEASES
ANTIRETROVIRAL THERAPY
RISK-FACTORS
IMMIGRANTS
EPIDEMIOLOGY
IMPACT
AREA
POPULATIONS
MIGRATION
COUNTRIES
Infectious Diseases
Epidemiology
SDG 3 - Good Health and Well-being
description BACKGROUND: International human migration has been rapidly growing. Migrants coming from low and middle income countries continue to be considerably vulnerable and at higher risk for infectious diseases, namely HIV (Human Immunodeficiency Virus) and tuberculosis (TB). In Europe, the number of patients with HIV-TB co-infection has been increasing and migration could be one of the potential driving forces. OBJECTIVE: This systematic review aims to improve the understanding on the burden of HIV-TB co-infection among migrants in Europe and to assess whether these populations are particularly vulnerable to this co-infection compared to nationals. DESIGN: MEDLINE®, Web of Science® and Scopus® databases were searched from March to April 2016 using combinations of keywords. Titles and abstracts were screened and studies meeting the inclusion criteria proceeded for full-text revision. These articles were then selected for data extraction on the prevalence, incidence and mortality. RESULTS: The majority of HIV-TB prevalence data reported in the analysed studies, including extrapulmonary/disseminated TB forms, was higher among migrant vs. nationals, some of the studies even showing increasing trends over time. Additionally, while HIV-TB incidence rates have decreased among migrants and nationals, migrants are still at a higher risk for this co-infection. Migrants with HIV-TB co-infection were also more prone to unsuccessful treatment outcomes, death and drug resistant TB. However, contradicting results also showed lower mortality compared to nationals. CONCLUSIONS: Overall, a disproportionate vulnerability of migrants to acquire the HIV-TB co-infection was observed across studies. Such vulnerability has been associated to low socioeconomic status, poor living conditions and limited access to healthcare. Adequate social support, early detection, appropriate treatment, and adequate access to healthcare are key improvements to tackle HIV-TB co-infection among these populations.
publishDate 2017
dc.date.none.fl_str_mv 2017-09-28
2017-09-28T00:00:00Z
2018-05-10T22:18:15Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/36492
url http://hdl.handle.net/10362/36492
dc.language.iso.fl_str_mv eng
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dc.relation.none.fl_str_mv 1932-6203
PURE: 3256045
https://doi.org/10.1371/journal.pone.0185526
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eu_rights_str_mv openAccess
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