Bronchodilator reversibility : what are the differences between asthma and chronic obstructive pulmonary disease?

Detalhes bibliográficos
Autor(a) principal: Barros, Raquel
Data de Publicação: 2020
Outros Autores: Camões De Araújo, Patrícia, Mourato, Cláudia, Budzak, Khrystyna, Oliveira, Ana, Bárbara, Cristina
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10451/45685
Resumo: © 2020 Eurasian Journal of Pulmonology Published by Wolters Kluwer - Medknow.
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spelling Bronchodilator reversibility : what are the differences between asthma and chronic obstructive pulmonary disease?AsthmaBronchodilation criteriaBronchodilator responseChronic obstructive pulmonary disease© 2020 Eurasian Journal of Pulmonology Published by Wolters Kluwer - Medknow.Introduction: Currently, the bronchodilator reversibility is not recommended to differentiate asthma from chronic obstructive pulmonary disease (COPD); however, physiopathological specificities of each disease contribute to the differences in response to the drug. Objectives: The objective of this study is to evaluate the differences in bronchodilator response between asthmatic and COPD patients and to determine which of the bronchodilation criteria have the best ability to detect the positive response in these patients. Materials and methods: This was a cross-sectional study. The sample included 104 patients with asthma or COPD who performed lung function tests between January and March 2018. The whole sample was analyzed according to postbronchodilator variation (Δ) of lung function parameters, and the postbronchodilator reversibility was characterized using a multiple bronchodilation criteria. The drug used in reversibility test was salbutamol. Results: In this study, Δ forced-expiratory volume in the 1st s (ΔFEV1) and a Δ Raw was statistically higher in the group with asthma compared with the group with COPD. In the asthma group, the criteria ↓ functional residual capacity (FRC) ≥10%, ↓Raw ≥ 35%, ↑ forced expiratory flow between 25% and 75% of vital capacity (FEF25%–75%) ≥20% and ↑ FEV1 and / or ↑ forced vital capacity ≥12% and 200 mL were those that presented a greater capacity of detecting a positive response to bronchodilator. The criteria ↑ FEF25%–75%≥20% and ↓ FRC ≥ 10% were those that had the greater ability of detecting airway reversibility in COPD group. Conclusion: The analysis of postbronchodilator FEV1 and raw modifications as well as the using of a combination of multiple bronchodilation criteria contribute to a deeper characterization of bronchodilator reversibility in asthma and COPD.Wolters KluwerRepositório da Universidade de LisboaBarros, RaquelCamões De Araújo, PatríciaMourato, CláudiaBudzak, KhrystynaOliveira, AnaBárbara, Cristina2021-01-06T14:23:24Z20202020-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/45685engEurasian J Pulmonol 2020;22:169-742148-362010.4103/ejop.ejop_16_202148-5402info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-08T16:47:38Zoai:repositorio.ul.pt:10451/45685Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T21:58:02.757086Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Bronchodilator reversibility : what are the differences between asthma and chronic obstructive pulmonary disease?
title Bronchodilator reversibility : what are the differences between asthma and chronic obstructive pulmonary disease?
spellingShingle Bronchodilator reversibility : what are the differences between asthma and chronic obstructive pulmonary disease?
Barros, Raquel
Asthma
Bronchodilation criteria
Bronchodilator response
Chronic obstructive pulmonary disease
title_short Bronchodilator reversibility : what are the differences between asthma and chronic obstructive pulmonary disease?
title_full Bronchodilator reversibility : what are the differences between asthma and chronic obstructive pulmonary disease?
title_fullStr Bronchodilator reversibility : what are the differences between asthma and chronic obstructive pulmonary disease?
title_full_unstemmed Bronchodilator reversibility : what are the differences between asthma and chronic obstructive pulmonary disease?
title_sort Bronchodilator reversibility : what are the differences between asthma and chronic obstructive pulmonary disease?
author Barros, Raquel
author_facet Barros, Raquel
Camões De Araújo, Patrícia
Mourato, Cláudia
Budzak, Khrystyna
Oliveira, Ana
Bárbara, Cristina
author_role author
author2 Camões De Araújo, Patrícia
Mourato, Cláudia
Budzak, Khrystyna
Oliveira, Ana
Bárbara, Cristina
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv Barros, Raquel
Camões De Araújo, Patrícia
Mourato, Cláudia
Budzak, Khrystyna
Oliveira, Ana
Bárbara, Cristina
dc.subject.por.fl_str_mv Asthma
Bronchodilation criteria
Bronchodilator response
Chronic obstructive pulmonary disease
topic Asthma
Bronchodilation criteria
Bronchodilator response
Chronic obstructive pulmonary disease
description © 2020 Eurasian Journal of Pulmonology Published by Wolters Kluwer - Medknow.
publishDate 2020
dc.date.none.fl_str_mv 2020
2020-01-01T00:00:00Z
2021-01-06T14:23:24Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10451/45685
url http://hdl.handle.net/10451/45685
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Eurasian J Pulmonol 2020;22:169-74
2148-3620
10.4103/ejop.ejop_16_20
2148-5402
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Wolters Kluwer
publisher.none.fl_str_mv Wolters Kluwer
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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