Growth patterns, metabolic indicators and osteoarticular status in the Lusitano horse : a longitudinal study
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.5/21896 |
Resumo: | Research Areas: Science & Technology - Other Topics |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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7160 |
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Growth patterns, metabolic indicators and osteoarticular status in the Lusitano horse : a longitudinal study3rd metacarpal bonedevelopmental orthopedic diseaseosteochondral conditions joccage-related-changesLusitano Horseparathyroid-hormonequantitative ultrasonographynoninvasive assessmentserum concentrationsskeletal metabolismResearch Areas: Science & Technology - Other TopicsDevelopment of a healthy musculoskeletal system is of high concern for horse breeders and users. A longitudinal field study was performed in order to: (i) evaluate growth patterns and long-term changes on bone quality, bone metabolism, growth factors and metabolic variables in the Lusitano horse; and (ii) retrospectively assess whether these changes were related with radiographic findings regarding osteochondrosis-like lesions (OC) at the onset of training. Thirty-four Lusitano foals born and raised at four stud-farms, were periodically weighed (BW), and measured (withers height-WH) from birth to 36 months of age. On the same days, blood samples were collected for determination of osteocalcin, bone alkaline phosphatase, insulin-like growth factor I (IGF-I), leptin, insulin, glucose, parathyroid hormone (PTH), calcium, phosphorus and magnesium plasma concentrations, and quantitative ultrasound measurements were performed on the right third metacarpal bone (McIII). At the end of the study horses underwent radiographic examination of the four fetlocks, hocks and stifles. According to their radiographic status (OC negative vs. OC positive), Richards growth function was adjusted to BW and WH data. Instantaneous BW and WH growth rates (BW IADG and WH IADG) were calculated for each foal, from the resolution of the first derivative of growth models for seven age-classes. The presence of radiographic findings compatible with OC at the onset of training was associated with changes in BW and WH growth rates. Positive horses presented higher BW IADG from six to 18 months of age and lower WH IADG before 45 days of age (P<0.001). Speed of sound measurements (SOS), bone markers, growth factors and other metabolic variables change markedly with age (P<0.01). OC positive horses tended to have lower SOS values at the lateral region of McIII, lower IGF-I, and higher insulin and PTH concentrations (P<0.1). This study provides indirect evidence that monitoring foals’ growth during the first year of life may be of assistance in managing the occurrence of OC. Further studies with a higher number of animals and a controlled feed intake should be pursued.Chris Rogers, Massey University, NEWZEALANDRepositório da Universidade de LisboaFradinho, M.J.Mateus, LuisaBernardes, NunoBessa, R.J.B.Caldeira, Rui M.Ferreira-Dias, Graça2021-09-21T22:57:18Z2019-07-172019-07-17T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.5/21896engFradinho MJ, Mateus L, Bernardes N, Bessa RJB, Caldeira RM, Ferreira-Dias G 2019. Growth patterns, metabolic indicators and osteoarticular status in the Lusitano horse : a longitudinal study. PLoSONE 14(7):e021990010.1371/journal.pone.02199001932-6203info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-03-06T14:51:27Zoai:www.repository.utl.pt:10400.5/21896Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T17:06:26.173040Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Growth patterns, metabolic indicators and osteoarticular status in the Lusitano horse : a longitudinal study |
title |
Growth patterns, metabolic indicators and osteoarticular status in the Lusitano horse : a longitudinal study |
spellingShingle |
Growth patterns, metabolic indicators and osteoarticular status in the Lusitano horse : a longitudinal study Fradinho, M.J. 3rd metacarpal bone developmental orthopedic disease osteochondral conditions jocc age-related-changes Lusitano Horse parathyroid-hormone quantitative ultrasonography noninvasive assessment serum concentrations skeletal metabolism |
title_short |
Growth patterns, metabolic indicators and osteoarticular status in the Lusitano horse : a longitudinal study |
title_full |
Growth patterns, metabolic indicators and osteoarticular status in the Lusitano horse : a longitudinal study |
title_fullStr |
Growth patterns, metabolic indicators and osteoarticular status in the Lusitano horse : a longitudinal study |
title_full_unstemmed |
Growth patterns, metabolic indicators and osteoarticular status in the Lusitano horse : a longitudinal study |
title_sort |
Growth patterns, metabolic indicators and osteoarticular status in the Lusitano horse : a longitudinal study |
author |
Fradinho, M.J. |
author_facet |
Fradinho, M.J. Mateus, Luisa Bernardes, Nuno Bessa, R.J.B. Caldeira, Rui M. Ferreira-Dias, Graça |
author_role |
author |
author2 |
Mateus, Luisa Bernardes, Nuno Bessa, R.J.B. Caldeira, Rui M. Ferreira-Dias, Graça |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
Repositório da Universidade de Lisboa |
dc.contributor.author.fl_str_mv |
Fradinho, M.J. Mateus, Luisa Bernardes, Nuno Bessa, R.J.B. Caldeira, Rui M. Ferreira-Dias, Graça |
dc.subject.por.fl_str_mv |
3rd metacarpal bone developmental orthopedic disease osteochondral conditions jocc age-related-changes Lusitano Horse parathyroid-hormone quantitative ultrasonography noninvasive assessment serum concentrations skeletal metabolism |
topic |
3rd metacarpal bone developmental orthopedic disease osteochondral conditions jocc age-related-changes Lusitano Horse parathyroid-hormone quantitative ultrasonography noninvasive assessment serum concentrations skeletal metabolism |
description |
Research Areas: Science & Technology - Other Topics |
publishDate |
2019 |
dc.date.none.fl_str_mv |
2019-07-17 2019-07-17T00:00:00Z 2021-09-21T22:57:18Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.5/21896 |
url |
http://hdl.handle.net/10400.5/21896 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Fradinho MJ, Mateus L, Bernardes N, Bessa RJB, Caldeira RM, Ferreira-Dias G 2019. Growth patterns, metabolic indicators and osteoarticular status in the Lusitano horse : a longitudinal study. PLoSONE 14(7):e0219900 10.1371/journal.pone.0219900 1932-6203 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Chris Rogers, Massey University, NEWZEALAND |
publisher.none.fl_str_mv |
Chris Rogers, Massey University, NEWZEALAND |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
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1799131156913848320 |