Uncharted Source of Medicinal Products : The Case of the Hedychium Genus
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.3/5818 |
Resumo: | A current research topic of great interest is the study of the therapeutic properties of plants and of their bioactive secondary metabolites. Plants have been used to treat all types of health problems from allergies to cancer, in addition to their use in the perfumery industry and as food. Hedychium species are among those plants used in folk medicine in several countries and several works have been reported to verify if and how effectively these plants exert the effects reported in folk medicine, studying their essential oils, extracts and pure secondary metabolites. Hedychium coronarium and Hedychium spicatum are the most studied species. Interesting compounds have been identified like coronarin D, which possesses antibacterial, antifungal and antitumor activities, as well as isocoronarin D, linalool and villosin that exhibit better cytotoxicity towards tumor cell lines than the reference compounds used, with villosin not affecting the non-tumor cell line. Linalool and α-pinene are the most active compounds found in Hedychium essential oils, while β-pinene is identified as the most widespread compound, being reported in 12 different Hedychium species. Since only some Hedychium species have been investigated, this review hopes to shed some light on the uncharted territory that is the Hedychium genus. |
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Uncharted Source of Medicinal Products : The Case of the Hedychium GenusHedychiumCoronarin DVillosinTraditional MedicineAnti-acetylcholinesteraseAntidiabeticAnti-inflammatoryAntimicrobialAntioxidantAntitumorA current research topic of great interest is the study of the therapeutic properties of plants and of their bioactive secondary metabolites. Plants have been used to treat all types of health problems from allergies to cancer, in addition to their use in the perfumery industry and as food. Hedychium species are among those plants used in folk medicine in several countries and several works have been reported to verify if and how effectively these plants exert the effects reported in folk medicine, studying their essential oils, extracts and pure secondary metabolites. Hedychium coronarium and Hedychium spicatum are the most studied species. Interesting compounds have been identified like coronarin D, which possesses antibacterial, antifungal and antitumor activities, as well as isocoronarin D, linalool and villosin that exhibit better cytotoxicity towards tumor cell lines than the reference compounds used, with villosin not affecting the non-tumor cell line. Linalool and α-pinene are the most active compounds found in Hedychium essential oils, while β-pinene is identified as the most widespread compound, being reported in 12 different Hedychium species. Since only some Hedychium species have been investigated, this review hopes to shed some light on the uncharted territory that is the Hedychium genus.This research was funded by project MACBIOPEST (MAC2/1.1a/289), program Interreg MAC 2014–2020 co-financed by DRCT (Azores Regional Government), supporting W.R. Tavares’s grant, as well as by FCT—Fundação para a Ciência e Tecnologia, the European Union, QREN, FEDER, and COMPETE, through funding the cE3c center (UIDB/00329/2020) and the LAQV-REQUIMTE (UIDB/50006/2020).MDPIRepositório da Universidade dos AçoresTavares, Wilson R.Barreto, Maria do CarmoSeca, Ana M. L.2021-03-25T13:44:54Z2020-042020-04-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.3/5818engTavares, W.R., Barreto, M.C. & Seca, A.M.L. (2020). Uncharted source of medicinal products, the case of the Hedychium. “Medicines”, 7, 23. DOI: 10.3390/medicines7050023.2305-632010.3390/medicines7050023http://europepmc.org/articles/PMC7281329https://www.ncbi.nlm.nih.gov/pubmed/32354114info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-12-20T14:34:12Zoai:repositorio.uac.pt:10400.3/5818Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:28:02.018490Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Uncharted Source of Medicinal Products : The Case of the Hedychium Genus |
title |
Uncharted Source of Medicinal Products : The Case of the Hedychium Genus |
spellingShingle |
Uncharted Source of Medicinal Products : The Case of the Hedychium Genus Tavares, Wilson R. Hedychium Coronarin D Villosin Traditional Medicine Anti-acetylcholinesterase Antidiabetic Anti-inflammatory Antimicrobial Antioxidant Antitumor |
title_short |
Uncharted Source of Medicinal Products : The Case of the Hedychium Genus |
title_full |
Uncharted Source of Medicinal Products : The Case of the Hedychium Genus |
title_fullStr |
Uncharted Source of Medicinal Products : The Case of the Hedychium Genus |
title_full_unstemmed |
Uncharted Source of Medicinal Products : The Case of the Hedychium Genus |
title_sort |
Uncharted Source of Medicinal Products : The Case of the Hedychium Genus |
author |
Tavares, Wilson R. |
author_facet |
Tavares, Wilson R. Barreto, Maria do Carmo Seca, Ana M. L. |
author_role |
author |
author2 |
Barreto, Maria do Carmo Seca, Ana M. L. |
author2_role |
author author |
dc.contributor.none.fl_str_mv |
Repositório da Universidade dos Açores |
dc.contributor.author.fl_str_mv |
Tavares, Wilson R. Barreto, Maria do Carmo Seca, Ana M. L. |
dc.subject.por.fl_str_mv |
Hedychium Coronarin D Villosin Traditional Medicine Anti-acetylcholinesterase Antidiabetic Anti-inflammatory Antimicrobial Antioxidant Antitumor |
topic |
Hedychium Coronarin D Villosin Traditional Medicine Anti-acetylcholinesterase Antidiabetic Anti-inflammatory Antimicrobial Antioxidant Antitumor |
description |
A current research topic of great interest is the study of the therapeutic properties of plants and of their bioactive secondary metabolites. Plants have been used to treat all types of health problems from allergies to cancer, in addition to their use in the perfumery industry and as food. Hedychium species are among those plants used in folk medicine in several countries and several works have been reported to verify if and how effectively these plants exert the effects reported in folk medicine, studying their essential oils, extracts and pure secondary metabolites. Hedychium coronarium and Hedychium spicatum are the most studied species. Interesting compounds have been identified like coronarin D, which possesses antibacterial, antifungal and antitumor activities, as well as isocoronarin D, linalool and villosin that exhibit better cytotoxicity towards tumor cell lines than the reference compounds used, with villosin not affecting the non-tumor cell line. Linalool and α-pinene are the most active compounds found in Hedychium essential oils, while β-pinene is identified as the most widespread compound, being reported in 12 different Hedychium species. Since only some Hedychium species have been investigated, this review hopes to shed some light on the uncharted territory that is the Hedychium genus. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-04 2020-04-01T00:00:00Z 2021-03-25T13:44:54Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.3/5818 |
url |
http://hdl.handle.net/10400.3/5818 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Tavares, W.R., Barreto, M.C. & Seca, A.M.L. (2020). Uncharted source of medicinal products, the case of the Hedychium. “Medicines”, 7, 23. DOI: 10.3390/medicines7050023. 2305-6320 10.3390/medicines7050023 http://europepmc.org/articles/PMC7281329 https://www.ncbi.nlm.nih.gov/pubmed/32354114 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
MDPI |
publisher.none.fl_str_mv |
MDPI |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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