CUTANEOUS SARCOMA – FROM DIAGNOSIS TO TREATMENT

Detalhes bibliográficos
Autor(a) principal: Fernandes, Sónia
Data de Publicação: 2013
Outros Autores: Pinto, Gabriela Marques, Moura, Cecília, Afonso, Ana, Cardoso, Jorge
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://doi.org/10.29021/spdv.70.3.7
Resumo: The clinical diagnosis of cutaneous sarcomas is not an easy task, mainly due to their complex and hetero- geneous nature. Differential diagnosis may be difficult because there is substantial overlap of clinical features between a sarcoma that develop in superficial tissues (skin and subcutaneous tissue) and benign neoplasm and inflammatory dermatoses. Although not frequent, some types of cutaneous sarcomas have great importance, as they can be associa- ted with recurrence, aggressive local growth or metastasis, and can present high morbi-mortality rates. The authors report five clinical-pathological cases of cutaneous sarcomas – Kaposi’s sarcoma, dermatofibrosarcoma protuberans, atypical fibroxanthoma, leiomyosarcoma and angiosarcoma. A review of the relevant literature about cutaneous sarcomas with particular interest to dermatologists is presented, and we highlight some important clinical, laboratorial, histological and therapeutic findings.KEYWORDS – Skin neoplasms; Sarcoma; Sarcoma, Kaposi; Dermatofibrosarcoma; Histiocytoma, benign fibrous; Leio- myosarcoma; Hemangiosarcomal liposarcoma; Nerve sheath neoplasms.
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spelling CUTANEOUS SARCOMA – FROM DIAGNOSIS TO TREATMENTSARCOMAS CUTÂNEOS – DO DIAGNÓSTICO AO TRATAMENTOThe clinical diagnosis of cutaneous sarcomas is not an easy task, mainly due to their complex and hetero- geneous nature. Differential diagnosis may be difficult because there is substantial overlap of clinical features between a sarcoma that develop in superficial tissues (skin and subcutaneous tissue) and benign neoplasm and inflammatory dermatoses. Although not frequent, some types of cutaneous sarcomas have great importance, as they can be associa- ted with recurrence, aggressive local growth or metastasis, and can present high morbi-mortality rates. The authors report five clinical-pathological cases of cutaneous sarcomas – Kaposi’s sarcoma, dermatofibrosarcoma protuberans, atypical fibroxanthoma, leiomyosarcoma and angiosarcoma. A review of the relevant literature about cutaneous sarcomas with particular interest to dermatologists is presented, and we highlight some important clinical, laboratorial, histological and therapeutic findings.KEYWORDS – Skin neoplasms; Sarcoma; Sarcoma, Kaposi; Dermatofibrosarcoma; Histiocytoma, benign fibrous; Leio- myosarcoma; Hemangiosarcomal liposarcoma; Nerve sheath neoplasms.O diagnóstico dos sarcomas cutâneos é desafiante, devido à complexidade e heterogeneidade deste gru- po de lesões, cuja apresentação nos tecidos superficiais (pele e tecido celular subcutâneo) impõe diagnóstico diferen- cial obrigatório com tumores benignos e processos inflamatórios. Apesar de serem tumores pouco frequentes alguns tipos assumem grande importância por serem localmente invasivos, com elevada morbi-mortalidade associada, taxas de recidiva local e metastização significativas. Os autores apresentam cinco casos clínico-patológicos de sarcomas cutâneos – sarcoma de Kaposi, dermatofibros- sarcoma protuberans, fibroxantoma atípico, leiomiossarcoma e angiossarcoma – e fazem uma breve revisão da literatura sobre os tipos de sarcoma cutâneo com maior interesse na Dermatologia, salientando os aspectos fisiopa- tológicos, clínicos, histopatológicos e terapêuticos particulares.PALAVRAS-CHAVE – Neoplasias da pele; Sarcoma, Sarcoma de Kaposi; Dermatofibrossarcoma protuberans; Fibro- xantoma atípico, Leiomiossarcoma; Angiossarcoma; Lipossarcoma, Neoplasia da bainha do nervo periférico.Sociedade Portuguesa de Dermatologia e Venereologia2013-01-13T00:00:00Zjournal articleinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://doi.org/10.29021/spdv.70.3.7oai:ojs.revista.spdv.com.pt:article/7Journal of the Portuguese Society of Dermatology and Venereology; Vol 70 No 3 (2012): Julho - Setembro; 319Revista da Sociedade Portuguesa de Dermatologia e Venereologia; v. 70 n. 3 (2012): Julho - Setembro; 3192182-24092182-2395reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://revista.spdv.com.pt/index.php/spdv/article/view/7https://doi.org/10.29021/spdv.70.3.7https://revista.spdv.com.pt/index.php/spdv/article/view/7/7Fernandes, SóniaPinto, Gabriela MarquesMoura, CecíliaAfonso, AnaCardoso, Jorgeinfo:eu-repo/semantics/openAccess2022-10-06T12:34:35Zoai:ojs.revista.spdv.com.pt:article/7Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:10:36.841123Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv CUTANEOUS SARCOMA – FROM DIAGNOSIS TO TREATMENT
SARCOMAS CUTÂNEOS – DO DIAGNÓSTICO AO TRATAMENTO
title CUTANEOUS SARCOMA – FROM DIAGNOSIS TO TREATMENT
spellingShingle CUTANEOUS SARCOMA – FROM DIAGNOSIS TO TREATMENT
Fernandes, Sónia
title_short CUTANEOUS SARCOMA – FROM DIAGNOSIS TO TREATMENT
title_full CUTANEOUS SARCOMA – FROM DIAGNOSIS TO TREATMENT
title_fullStr CUTANEOUS SARCOMA – FROM DIAGNOSIS TO TREATMENT
title_full_unstemmed CUTANEOUS SARCOMA – FROM DIAGNOSIS TO TREATMENT
title_sort CUTANEOUS SARCOMA – FROM DIAGNOSIS TO TREATMENT
author Fernandes, Sónia
author_facet Fernandes, Sónia
Pinto, Gabriela Marques
Moura, Cecília
Afonso, Ana
Cardoso, Jorge
author_role author
author2 Pinto, Gabriela Marques
Moura, Cecília
Afonso, Ana
Cardoso, Jorge
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Fernandes, Sónia
Pinto, Gabriela Marques
Moura, Cecília
Afonso, Ana
Cardoso, Jorge
description The clinical diagnosis of cutaneous sarcomas is not an easy task, mainly due to their complex and hetero- geneous nature. Differential diagnosis may be difficult because there is substantial overlap of clinical features between a sarcoma that develop in superficial tissues (skin and subcutaneous tissue) and benign neoplasm and inflammatory dermatoses. Although not frequent, some types of cutaneous sarcomas have great importance, as they can be associa- ted with recurrence, aggressive local growth or metastasis, and can present high morbi-mortality rates. The authors report five clinical-pathological cases of cutaneous sarcomas – Kaposi’s sarcoma, dermatofibrosarcoma protuberans, atypical fibroxanthoma, leiomyosarcoma and angiosarcoma. A review of the relevant literature about cutaneous sarcomas with particular interest to dermatologists is presented, and we highlight some important clinical, laboratorial, histological and therapeutic findings.KEYWORDS – Skin neoplasms; Sarcoma; Sarcoma, Kaposi; Dermatofibrosarcoma; Histiocytoma, benign fibrous; Leio- myosarcoma; Hemangiosarcomal liposarcoma; Nerve sheath neoplasms.
publishDate 2013
dc.date.none.fl_str_mv 2013-01-13T00:00:00Z
dc.type.driver.fl_str_mv journal article
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dc.identifier.uri.fl_str_mv https://doi.org/10.29021/spdv.70.3.7
oai:ojs.revista.spdv.com.pt:article/7
url https://doi.org/10.29021/spdv.70.3.7
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dc.relation.none.fl_str_mv https://revista.spdv.com.pt/index.php/spdv/article/view/7
https://doi.org/10.29021/spdv.70.3.7
https://revista.spdv.com.pt/index.php/spdv/article/view/7/7
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dc.publisher.none.fl_str_mv Sociedade Portuguesa de Dermatologia e Venereologia
publisher.none.fl_str_mv Sociedade Portuguesa de Dermatologia e Venereologia
dc.source.none.fl_str_mv Journal of the Portuguese Society of Dermatology and Venereology; Vol 70 No 3 (2012): Julho - Setembro; 319
Revista da Sociedade Portuguesa de Dermatologia e Venereologia; v. 70 n. 3 (2012): Julho - Setembro; 319
2182-2409
2182-2395
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