Low protein intake, physical activity, and physical function in European and North American community-dwelling older adults

Detalhes bibliográficos
Autor(a) principal: Mendonça, Nuno
Data de Publicação: 2021
Outros Autores: Hengeveld, Linda M, Visser, Marjolein, Presse, Nancy, Canhão, Helena, Simonsick, Eleanor M, Kritchevsky, Stephen B, Newman, Anne B, Gaudreau, Pierrette, Jagger, Carol
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/115881
Resumo: © The Author(s) 2021. Published by Oxford University Press on behalf of the American Society for Nutrition.
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spelling Low protein intake, physical activity, and physical function in European and North American community-dwelling older adultsa pooled analysis of four longitudinal aging cohortsproteinwalking speedgait speedphysical activityjoint modelsPROMISSolder adultsone-stage meta-analysisSDG 2 - Zero Hunger© The Author(s) 2021. Published by Oxford University Press on behalf of the American Society for Nutrition.BACKGROUND: Dietary protein may slow the decline in muscle mass and function with aging, making it a sensible candidate to prevent or modulate disability progression. At present, studies providing reliable estimates of the association between protein intake and physical function, and its interaction with physical activity (PA), in community-dwelling older adults are lacking. OBJECTIVES: We investigated the longitudinal relation between protein intake and physical function, and the interaction with PA. METHODS: We undertook a pooled analysis of individual participant data from cohorts in the PROMISS (PRevention Of Malnutrition In Senior Subjects in the European Union) consortium (the Health Aging and Body Composition Study, Quebec Longitudinal Study on Nutrition and Successful Aging, Longitudinal Aging Study Amsterdam, and Newcastle 85+) in which 5725 community-dwelling older adults were followed up to 8.5 y. The relation between protein intake and walking speed was determined using joint models (linear mixed-effects and Cox proportional hazards models) and the relation with mobility limitation was investigated using multistate models. RESULTS: Higher protein intake was modestly protective of decline in walking speed in a dose-dependent manner [e.g., protein intake ≥1.2 compared with 0.8 g/kg adjusted body weight (aBW)/d: β = 0.024, 95% CI: 0.009, 0.032 SD/y], with no clear indication of interaction with PA. Participants with protein intake ≥0.8 g/kg aBW/d had also a lower likelihood of incident mobility limitation, which was observed for each level of PA. This association seemed to be dose-dependent for difficulty walking but not for difficulty climbing stairs. No associations between protein intake and other mobility limitations transitions were observed. CONCLUSIONS: Higher daily protein intake can reduce physical function decline not only in older adults with protein intake below the current RDA of 0.8 g/kg BW/d, but also in those with a protein intake that is already considered sufficient. This dose-dependent association was observed for each level of PA, suggesting no clear synergistic association between protein intake and PA in relation to physical function.Centro de Estudos de Doenças Crónicas (CEDOC)NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)Comprehensive Health Research Centre (CHRC) - pólo NMSRUNMendonça, NunoHengeveld, Linda MVisser, MarjoleinPresse, NancyCanhão, HelenaSimonsick, Eleanor MKritchevsky, Stephen BNewman, Anne BGaudreau, PierretteJagger, Carol2021-04-20T22:50:59Z2021-072021-07-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10362/115881eng0002-9165PURE: 29159128https://doi.org/10.1093/ajcn/nqab051info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T04:58:24Zoai:run.unl.pt:10362/115881Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:42:52.065587Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Low protein intake, physical activity, and physical function in European and North American community-dwelling older adults
a pooled analysis of four longitudinal aging cohorts
title Low protein intake, physical activity, and physical function in European and North American community-dwelling older adults
spellingShingle Low protein intake, physical activity, and physical function in European and North American community-dwelling older adults
Mendonça, Nuno
protein
walking speed
gait speed
physical activity
joint models
PROMISS
older adults
one-stage meta-analysis
SDG 2 - Zero Hunger
title_short Low protein intake, physical activity, and physical function in European and North American community-dwelling older adults
title_full Low protein intake, physical activity, and physical function in European and North American community-dwelling older adults
title_fullStr Low protein intake, physical activity, and physical function in European and North American community-dwelling older adults
title_full_unstemmed Low protein intake, physical activity, and physical function in European and North American community-dwelling older adults
title_sort Low protein intake, physical activity, and physical function in European and North American community-dwelling older adults
author Mendonça, Nuno
author_facet Mendonça, Nuno
Hengeveld, Linda M
Visser, Marjolein
Presse, Nancy
Canhão, Helena
Simonsick, Eleanor M
Kritchevsky, Stephen B
Newman, Anne B
Gaudreau, Pierrette
Jagger, Carol
author_role author
author2 Hengeveld, Linda M
Visser, Marjolein
Presse, Nancy
Canhão, Helena
Simonsick, Eleanor M
Kritchevsky, Stephen B
Newman, Anne B
Gaudreau, Pierrette
Jagger, Carol
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Centro de Estudos de Doenças Crónicas (CEDOC)
NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
Comprehensive Health Research Centre (CHRC) - pólo NMS
RUN
dc.contributor.author.fl_str_mv Mendonça, Nuno
Hengeveld, Linda M
Visser, Marjolein
Presse, Nancy
Canhão, Helena
Simonsick, Eleanor M
Kritchevsky, Stephen B
Newman, Anne B
Gaudreau, Pierrette
Jagger, Carol
dc.subject.por.fl_str_mv protein
walking speed
gait speed
physical activity
joint models
PROMISS
older adults
one-stage meta-analysis
SDG 2 - Zero Hunger
topic protein
walking speed
gait speed
physical activity
joint models
PROMISS
older adults
one-stage meta-analysis
SDG 2 - Zero Hunger
description © The Author(s) 2021. Published by Oxford University Press on behalf of the American Society for Nutrition.
publishDate 2021
dc.date.none.fl_str_mv 2021-04-20T22:50:59Z
2021-07
2021-07-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/115881
url http://hdl.handle.net/10362/115881
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 0002-9165
PURE: 29159128
https://doi.org/10.1093/ajcn/nqab051
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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