Transmissible Mycobacterium tuberculosis Strains Share Genetic Markers and Immune Phenotypes

Detalhes bibliográficos
Autor(a) principal: Nebenzahl-Guimaraes, Hanna
Data de Publicação: 2017
Outros Autores: van Laarhoven, Arjan, Farhat, Maha R., Koeken, Valerie A. C. M., Mandemakers, Jornt J., Zomer, Aldert, van Hijum, Sacha A. F. T., Netea, Mihai G., Murray, Megan, van Crevel, Reinout, van Soolingen, Dick
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/1822/62014
Resumo: Successful transmission of tuberculosis depends on the interplay of human behavior, host immune responses, and Mycobacterium tuberculosis virulence factors. Previous studies have been focused on identifying host risk factors associated with increased transmission, but the contribution of specific genetic variations in mycobacterial strains themselves are still unknown.
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spelling Transmissible Mycobacterium tuberculosis Strains Share Genetic Markers and Immune PhenotypesGenetic MarkersImmunity, CellularMycobacterium tuberculosisPhenotypetuberculosistransmissionbacterial genomesimmunologyCiências Médicas::Medicina BásicaScience & TechnologySuccessful transmission of tuberculosis depends on the interplay of human behavior, host immune responses, and Mycobacterium tuberculosis virulence factors. Previous studies have been focused on identifying host risk factors associated with increased transmission, but the contribution of specific genetic variations in mycobacterial strains themselves are still unknown.This study was funded by the Portuguese Foundation for Science and Technology (FCT) (SFRH/BD/33902/2009 [H.N.-G.]).American Thoracic SocietyUniversidade do MinhoNebenzahl-Guimaraes, Hannavan Laarhoven, ArjanFarhat, Maha R.Koeken, Valerie A. C. M.Mandemakers, Jornt J.Zomer, Aldertvan Hijum, Sacha A. F. T.Netea, Mihai G.Murray, Meganvan Crevel, Reinoutvan Soolingen, Dick20172017-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/62014engNebenzahl-Guimaraes, H., van Laarhoven, A., Farhat, M. R., Koeken, V. A., Mandemakers, et. al. (2017). Transmissible Mycobacterium tuberculosis strains share genetic markers and immune phenotypes. American journal of respiratory and critical care medicine, 195(11), 1519-15271073-449X1535-497010.1164/rccm.201605-1042OC27997216https://www.atsjournals.org/doi/full/10.1164/rccm.201605-1042OCinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:34:13Zoai:repositorium.sdum.uminho.pt:1822/62014Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T19:29:50.420744Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Transmissible Mycobacterium tuberculosis Strains Share Genetic Markers and Immune Phenotypes
title Transmissible Mycobacterium tuberculosis Strains Share Genetic Markers and Immune Phenotypes
spellingShingle Transmissible Mycobacterium tuberculosis Strains Share Genetic Markers and Immune Phenotypes
Nebenzahl-Guimaraes, Hanna
Genetic Markers
Immunity, Cellular
Mycobacterium tuberculosis
Phenotype
tuberculosis
transmission
bacterial genomes
immunology
Ciências Médicas::Medicina Básica
Science & Technology
title_short Transmissible Mycobacterium tuberculosis Strains Share Genetic Markers and Immune Phenotypes
title_full Transmissible Mycobacterium tuberculosis Strains Share Genetic Markers and Immune Phenotypes
title_fullStr Transmissible Mycobacterium tuberculosis Strains Share Genetic Markers and Immune Phenotypes
title_full_unstemmed Transmissible Mycobacterium tuberculosis Strains Share Genetic Markers and Immune Phenotypes
title_sort Transmissible Mycobacterium tuberculosis Strains Share Genetic Markers and Immune Phenotypes
author Nebenzahl-Guimaraes, Hanna
author_facet Nebenzahl-Guimaraes, Hanna
van Laarhoven, Arjan
Farhat, Maha R.
Koeken, Valerie A. C. M.
Mandemakers, Jornt J.
Zomer, Aldert
van Hijum, Sacha A. F. T.
Netea, Mihai G.
Murray, Megan
van Crevel, Reinout
van Soolingen, Dick
author_role author
author2 van Laarhoven, Arjan
Farhat, Maha R.
Koeken, Valerie A. C. M.
Mandemakers, Jornt J.
Zomer, Aldert
van Hijum, Sacha A. F. T.
Netea, Mihai G.
Murray, Megan
van Crevel, Reinout
van Soolingen, Dick
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade do Minho
dc.contributor.author.fl_str_mv Nebenzahl-Guimaraes, Hanna
van Laarhoven, Arjan
Farhat, Maha R.
Koeken, Valerie A. C. M.
Mandemakers, Jornt J.
Zomer, Aldert
van Hijum, Sacha A. F. T.
Netea, Mihai G.
Murray, Megan
van Crevel, Reinout
van Soolingen, Dick
dc.subject.por.fl_str_mv Genetic Markers
Immunity, Cellular
Mycobacterium tuberculosis
Phenotype
tuberculosis
transmission
bacterial genomes
immunology
Ciências Médicas::Medicina Básica
Science & Technology
topic Genetic Markers
Immunity, Cellular
Mycobacterium tuberculosis
Phenotype
tuberculosis
transmission
bacterial genomes
immunology
Ciências Médicas::Medicina Básica
Science & Technology
description Successful transmission of tuberculosis depends on the interplay of human behavior, host immune responses, and Mycobacterium tuberculosis virulence factors. Previous studies have been focused on identifying host risk factors associated with increased transmission, but the contribution of specific genetic variations in mycobacterial strains themselves are still unknown.
publishDate 2017
dc.date.none.fl_str_mv 2017
2017-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/1822/62014
url http://hdl.handle.net/1822/62014
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Nebenzahl-Guimaraes, H., van Laarhoven, A., Farhat, M. R., Koeken, V. A., Mandemakers, et. al. (2017). Transmissible Mycobacterium tuberculosis strains share genetic markers and immune phenotypes. American journal of respiratory and critical care medicine, 195(11), 1519-1527
1073-449X
1535-4970
10.1164/rccm.201605-1042OC
27997216
https://www.atsjournals.org/doi/full/10.1164/rccm.201605-1042OC
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv American Thoracic Society
publisher.none.fl_str_mv American Thoracic Society
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
_version_ 1799132800233766912

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