MD Automatic epicardial fat segmentation and volume quantification on non-contrast Cardiac Computed Tomography
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10362/150293 |
Resumo: | Epicardial Fat Volume (EFV) represents a valuable predictor of cardio- and cerebrovascular events. However, the manual procedures for EFV calculation, diffused in clinical practice, are highly time-consuming for technicians or physicians and often involve significant intra- or inter-observer variances. To reduce the processing time and improve results repeatability, we propose a computer-assisted tool that automatically performs epicardial fat segmentation and volume quantification on non-contrast cardiac Computed Tomography (CT). The proposed algorithm prioritizes the use of basic image techniques, promoting lower computational complexity. The heart region is selected using Otsu’s Method, Template Matching and Connected Component Analysis. Then, to refine the pericardium delineation, convex hull is applied. Lastly, epicardial fat is segmented by thresholding. In addition to the algorithm, an intuitive software (HARTA) was developed for clinical use, allowing human intervention for adjustments. A set of 878 non-contrast cardiac CT images was used to validate the method. Using HARTA, the average time to segment the epicardial fat on a CT was 15.5 ± 2.42 s, while manually 10 to 26 min were required. Epicardial fat segmentation was evaluated obtaining an accuracy of 98.83% and a Dice Similarity Coefficient of 0.7730. EFV automatic quantification presents Pearson and Spearman correlation coefficients of 0.9366 and 0.8773, respectively. The proposed tool presents potential to be used in clinical contexts, assisting cardiologists to achieve faster and accurate EFV, leading towards personalized diagnosis and therapy. The human intervention component can also improve the automatic results and insure the credibility of this diagnostic support system. The software hereby presented is available for public access at GitHub. |
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MD Automatic epicardial fat segmentation and volume quantification on non-contrast Cardiac Computed TomographyEpicardial fat volumeCardiac adipose tissue quantificationAutomatic segmentationNon-contrast cardiac CTBasic image analysisComputer-assisted toolEpicardial Fat Volume (EFV) represents a valuable predictor of cardio- and cerebrovascular events. However, the manual procedures for EFV calculation, diffused in clinical practice, are highly time-consuming for technicians or physicians and often involve significant intra- or inter-observer variances. To reduce the processing time and improve results repeatability, we propose a computer-assisted tool that automatically performs epicardial fat segmentation and volume quantification on non-contrast cardiac Computed Tomography (CT). The proposed algorithm prioritizes the use of basic image techniques, promoting lower computational complexity. The heart region is selected using Otsu’s Method, Template Matching and Connected Component Analysis. Then, to refine the pericardium delineation, convex hull is applied. Lastly, epicardial fat is segmented by thresholding. In addition to the algorithm, an intuitive software (HARTA) was developed for clinical use, allowing human intervention for adjustments. A set of 878 non-contrast cardiac CT images was used to validate the method. Using HARTA, the average time to segment the epicardial fat on a CT was 15.5 ± 2.42 s, while manually 10 to 26 min were required. Epicardial fat segmentation was evaluated obtaining an accuracy of 98.83% and a Dice Similarity Coefficient of 0.7730. EFV automatic quantification presents Pearson and Spearman correlation coefficients of 0.9366 and 0.8773, respectively. The proposed tool presents potential to be used in clinical contexts, assisting cardiologists to achieve faster and accurate EFV, leading towards personalized diagnosis and therapy. The human intervention component can also improve the automatic results and insure the credibility of this diagnostic support system. The software hereby presented is available for public access at GitHub.UNINOVA-Instituto de Desenvolvimento de Novas TecnologiasCTS - Centro de Tecnologia e SistemasDEE2010-C1 Sistemas Digitais e PercepcionaisDEE - Departamento de Engenharia Electrotécnica e de ComputadoresDF – Departamento de FísicaRUNRebelo, Ana FilipaFerreira, António MiguelFonseca, José M.2023-03-09T22:28:39Z20222022-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article12application/pdfhttp://hdl.handle.net/10362/150293eng2666-9900PURE: 55190839https://doi.org/10.1016/j.cmpbup.2022.100079info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:32:12Zoai:run.unl.pt:10362/150293Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:54:02.346143Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
MD Automatic epicardial fat segmentation and volume quantification on non-contrast Cardiac Computed Tomography |
title |
MD Automatic epicardial fat segmentation and volume quantification on non-contrast Cardiac Computed Tomography |
spellingShingle |
MD Automatic epicardial fat segmentation and volume quantification on non-contrast Cardiac Computed Tomography Rebelo, Ana Filipa Epicardial fat volume Cardiac adipose tissue quantification Automatic segmentation Non-contrast cardiac CT Basic image analysis Computer-assisted tool |
title_short |
MD Automatic epicardial fat segmentation and volume quantification on non-contrast Cardiac Computed Tomography |
title_full |
MD Automatic epicardial fat segmentation and volume quantification on non-contrast Cardiac Computed Tomography |
title_fullStr |
MD Automatic epicardial fat segmentation and volume quantification on non-contrast Cardiac Computed Tomography |
title_full_unstemmed |
MD Automatic epicardial fat segmentation and volume quantification on non-contrast Cardiac Computed Tomography |
title_sort |
MD Automatic epicardial fat segmentation and volume quantification on non-contrast Cardiac Computed Tomography |
author |
Rebelo, Ana Filipa |
author_facet |
Rebelo, Ana Filipa Ferreira, António Miguel Fonseca, José M. |
author_role |
author |
author2 |
Ferreira, António Miguel Fonseca, José M. |
author2_role |
author author |
dc.contributor.none.fl_str_mv |
UNINOVA-Instituto de Desenvolvimento de Novas Tecnologias CTS - Centro de Tecnologia e Sistemas DEE2010-C1 Sistemas Digitais e Percepcionais DEE - Departamento de Engenharia Electrotécnica e de Computadores DF – Departamento de Física RUN |
dc.contributor.author.fl_str_mv |
Rebelo, Ana Filipa Ferreira, António Miguel Fonseca, José M. |
dc.subject.por.fl_str_mv |
Epicardial fat volume Cardiac adipose tissue quantification Automatic segmentation Non-contrast cardiac CT Basic image analysis Computer-assisted tool |
topic |
Epicardial fat volume Cardiac adipose tissue quantification Automatic segmentation Non-contrast cardiac CT Basic image analysis Computer-assisted tool |
description |
Epicardial Fat Volume (EFV) represents a valuable predictor of cardio- and cerebrovascular events. However, the manual procedures for EFV calculation, diffused in clinical practice, are highly time-consuming for technicians or physicians and often involve significant intra- or inter-observer variances. To reduce the processing time and improve results repeatability, we propose a computer-assisted tool that automatically performs epicardial fat segmentation and volume quantification on non-contrast cardiac Computed Tomography (CT). The proposed algorithm prioritizes the use of basic image techniques, promoting lower computational complexity. The heart region is selected using Otsu’s Method, Template Matching and Connected Component Analysis. Then, to refine the pericardium delineation, convex hull is applied. Lastly, epicardial fat is segmented by thresholding. In addition to the algorithm, an intuitive software (HARTA) was developed for clinical use, allowing human intervention for adjustments. A set of 878 non-contrast cardiac CT images was used to validate the method. Using HARTA, the average time to segment the epicardial fat on a CT was 15.5 ± 2.42 s, while manually 10 to 26 min were required. Epicardial fat segmentation was evaluated obtaining an accuracy of 98.83% and a Dice Similarity Coefficient of 0.7730. EFV automatic quantification presents Pearson and Spearman correlation coefficients of 0.9366 and 0.8773, respectively. The proposed tool presents potential to be used in clinical contexts, assisting cardiologists to achieve faster and accurate EFV, leading towards personalized diagnosis and therapy. The human intervention component can also improve the automatic results and insure the credibility of this diagnostic support system. The software hereby presented is available for public access at GitHub. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022 2022-01-01T00:00:00Z 2023-03-09T22:28:39Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10362/150293 |
url |
http://hdl.handle.net/10362/150293 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
2666-9900 PURE: 55190839 https://doi.org/10.1016/j.cmpbup.2022.100079 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
12 application/pdf |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
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1799138130465390592 |