From Chronic Alcohol Consumption to Coma: Report of an Uncommon Cause

Detalhes bibliográficos
Autor(a) principal: Melo e Silva, João Pedro
Data de Publicação: 2023
Outros Autores: Soares Dionísio, Antony, Barbosa Mateus, Daniela, Pais Silva, Filipa, Gonçalves Pereira, João
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.26/45751
Resumo: Marchiafava-Bignami disease is a rare condition characterized by demyelination of the corpus callosum that can evolve into necrosis. It is associated with thiamine deficiency, chronic alcohol consumption, and less frequently, severe malnutrition. The diagnosis is based on clinical presentation - altered mental state and changes in a neurological examination - and on neuroimaging studies, especially magnetic resonance imaging. Treatment with parenteral thiamine is recommended. The authors present a case of a 50-year-old male, with chronic alcohol abuse and malnutrition, admitted to the hospital with an acute form of the Marchiafava-Bignami disease. An early diagnosis and treatment facilitated neurological and cognitive recovery.
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spelling From Chronic Alcohol Consumption to Coma: Report of an Uncommon Causemarchiafava-bignami diseasethiamine deficiencydemyelinationcorpus callosumcomaalcoholismMarchiafava-Bignami disease is a rare condition characterized by demyelination of the corpus callosum that can evolve into necrosis. It is associated with thiamine deficiency, chronic alcohol consumption, and less frequently, severe malnutrition. The diagnosis is based on clinical presentation - altered mental state and changes in a neurological examination - and on neuroimaging studies, especially magnetic resonance imaging. Treatment with parenteral thiamine is recommended. The authors present a case of a 50-year-old male, with chronic alcohol abuse and malnutrition, admitted to the hospital with an acute form of the Marchiafava-Bignami disease. An early diagnosis and treatment facilitated neurological and cognitive recovery.Repositório ComumMelo e Silva, João PedroSoares Dionísio, AntonyBarbosa Mateus, DanielaPais Silva, FilipaGonçalves Pereira, João2023-07-27T10:45:54Z2023-03-202023-03-20T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.26/45751eng10.7759/cureus.36411info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-10T05:02:05Zoai:comum.rcaap.pt:10400.26/45751Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T22:35:40.627020Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv From Chronic Alcohol Consumption to Coma: Report of an Uncommon Cause
title From Chronic Alcohol Consumption to Coma: Report of an Uncommon Cause
spellingShingle From Chronic Alcohol Consumption to Coma: Report of an Uncommon Cause
Melo e Silva, João Pedro
marchiafava-bignami disease
thiamine deficiency
demyelination
corpus callosum
coma
alcoholism
title_short From Chronic Alcohol Consumption to Coma: Report of an Uncommon Cause
title_full From Chronic Alcohol Consumption to Coma: Report of an Uncommon Cause
title_fullStr From Chronic Alcohol Consumption to Coma: Report of an Uncommon Cause
title_full_unstemmed From Chronic Alcohol Consumption to Coma: Report of an Uncommon Cause
title_sort From Chronic Alcohol Consumption to Coma: Report of an Uncommon Cause
author Melo e Silva, João Pedro
author_facet Melo e Silva, João Pedro
Soares Dionísio, Antony
Barbosa Mateus, Daniela
Pais Silva, Filipa
Gonçalves Pereira, João
author_role author
author2 Soares Dionísio, Antony
Barbosa Mateus, Daniela
Pais Silva, Filipa
Gonçalves Pereira, João
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Repositório Comum
dc.contributor.author.fl_str_mv Melo e Silva, João Pedro
Soares Dionísio, Antony
Barbosa Mateus, Daniela
Pais Silva, Filipa
Gonçalves Pereira, João
dc.subject.por.fl_str_mv marchiafava-bignami disease
thiamine deficiency
demyelination
corpus callosum
coma
alcoholism
topic marchiafava-bignami disease
thiamine deficiency
demyelination
corpus callosum
coma
alcoholism
description Marchiafava-Bignami disease is a rare condition characterized by demyelination of the corpus callosum that can evolve into necrosis. It is associated with thiamine deficiency, chronic alcohol consumption, and less frequently, severe malnutrition. The diagnosis is based on clinical presentation - altered mental state and changes in a neurological examination - and on neuroimaging studies, especially magnetic resonance imaging. Treatment with parenteral thiamine is recommended. The authors present a case of a 50-year-old male, with chronic alcohol abuse and malnutrition, admitted to the hospital with an acute form of the Marchiafava-Bignami disease. An early diagnosis and treatment facilitated neurological and cognitive recovery.
publishDate 2023
dc.date.none.fl_str_mv 2023-07-27T10:45:54Z
2023-03-20
2023-03-20T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.26/45751
url http://hdl.handle.net/10400.26/45751
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.7759/cureus.36411
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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