Targeting biofilms using phages and their enzymes

Detalhes bibliográficos
Autor(a) principal: Azeredo, Joana
Data de Publicação: 2021
Outros Autores: García, Pilar, Drulis-Kawa, Zuzanna
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/1822/70786
Resumo: "Available online 10 March 2021"
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spelling Targeting biofilms using phages and their enzymesScience & Technology"Available online 10 March 2021"The complex biofilm architecture composed of extracellular polymeric structures (EPS) provides a protective shield to physiologically diverse bacterial cells immersed in its structure. The evolutionary interplay between bacteria and their viruses (phages) forced the latter ones to develop specific strategies to overcome the biofilm defensive barriers and kill sessile cells. Phages are equipped with a wide panel of enzyme-degrading EPS macromolecules which together are powerful weapons to combat biofilms. Antibiofilm performance can be achieved by combining phages or phage-borne enzymes with other antimicrobials such as antibiotics. Nevertheless, a variety of enzymes encoded in phage genomes still need to be explored. To advance in biofilm control strategies we must deepen the understanding of the biofilm biology itself, as well as discover and better exploit the unlimited antibacterial potential of phages.JA was supported by the Portuguese Foundation for Science and Technology (FCT) under the scope of the strategic funding of UIDB/04469/2020 unit. PG was supported by grants from Innovative Training Networks (ITN) Marie Skłodowska-Curie Actions H2020-MSCA-ITN2018. Reference 813439, and PID2019-105311RB-I00 (MICIU/AEI/FEDER, UE, Spain). ZDK was supported by the National Science Centre of Poland (Narodowe Centrum Nauki), grant numbers 2016/21/B/NZ6/01157 and 2017/26/M/NZ1/00233.info:eu-repo/semantics/publishedVersionElsevierUniversidade do MinhoAzeredo, JoanaGarcía, PilarDrulis-Kawa, Zuzanna2021-042021-04-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/70786engAzeredo, Joana; García, Pilar; Drulis-Kawa, Zuzanna, Targeting biofilms using phages and their enzymes. Current Opinion in Biotechnology, 68, 251-261, 20210958-16691879-042910.1016/j.copbio.2021.02.00233714050http://www.journals.elsevier.com/current-opinion-in-biotechnologyinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:18:24Zoai:repositorium.sdum.uminho.pt:1822/70786Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T19:11:13.210149Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Targeting biofilms using phages and their enzymes
title Targeting biofilms using phages and their enzymes
spellingShingle Targeting biofilms using phages and their enzymes
Azeredo, Joana
Science & Technology
title_short Targeting biofilms using phages and their enzymes
title_full Targeting biofilms using phages and their enzymes
title_fullStr Targeting biofilms using phages and their enzymes
title_full_unstemmed Targeting biofilms using phages and their enzymes
title_sort Targeting biofilms using phages and their enzymes
author Azeredo, Joana
author_facet Azeredo, Joana
García, Pilar
Drulis-Kawa, Zuzanna
author_role author
author2 García, Pilar
Drulis-Kawa, Zuzanna
author2_role author
author
dc.contributor.none.fl_str_mv Universidade do Minho
dc.contributor.author.fl_str_mv Azeredo, Joana
García, Pilar
Drulis-Kawa, Zuzanna
dc.subject.por.fl_str_mv Science & Technology
topic Science & Technology
description "Available online 10 March 2021"
publishDate 2021
dc.date.none.fl_str_mv 2021-04
2021-04-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/1822/70786
url http://hdl.handle.net/1822/70786
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Azeredo, Joana; García, Pilar; Drulis-Kawa, Zuzanna, Targeting biofilms using phages and their enzymes. Current Opinion in Biotechnology, 68, 251-261, 2021
0958-1669
1879-0429
10.1016/j.copbio.2021.02.002
33714050
http://www.journals.elsevier.com/current-opinion-in-biotechnology
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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