Passive direct methanol fuel cells acting as fully autonomous electrochemical biosensors

Detalhes bibliográficos
Autor(a) principal: Ferreira, Nádia S.
Data de Publicação: 2022
Outros Autores: Carneiro, Liliana P.T., Viezzer, Christian, Almeida, Maria J. T., Marques, Ana C., Pinto, Alexandra M. F. R., Fortunato, Elvira, Sales, M. Goreti F.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/150643
Resumo: Publisher Copyright: © 2022 The Author(s)
id RCAP_659e4e69b12247bcd408fea060f8e351
oai_identifier_str oai:run.unl.pt:10362/150643
network_acronym_str RCAP
network_name_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository_id_str 7160
spelling Passive direct methanol fuel cells acting as fully autonomous electrochemical biosensorsApplication to sarcosine detectionCancer biomarkerColour displayElectrochromic cellMolecularly imprinted polymerPassive direct methanol fuel cellSarcosineAnalytical ChemistryChemical Engineering(all)ElectrochemistrySDG 3 - Good Health and Well-beingPublisher Copyright: © 2022 The Author(s)This work describes an innovative electrochemical biosensor that advances its autonomy toward an equipment-free design. The biosensor is powered by a passive direct methanol fuel cell (DMFC) and signals the response via an electrochromic display. Briefly, the anode side of the DMFC power source was modified with a biosensor layer developed using molecularly imprinted polymer (MIP) technology to detect sarcosine (an amino acid derivative that is a potential cancer biomarker). The biosensor layer was anchored on the surface of the anode carbon electrode (carbon black with Pt/Ru, 40:20). This was done by bulk radical polymerization with acrylamide, bis-acrylamide, and vinyl phosphonic acid. This layer selectively interacted with sarcosine when integrated into the passive DMFC (single or multiple, in a stack of 4), which acted as a transducer element in a concentration-dependent process. Serial assembly of a stack of hybrid DMFC/biosensor devices triggered an external electrochromic cell (EC) that produced a colour change. Calibrations showed a concentration-dependent sarcosine response from 3.2 to 2000 µM, which is compatible with the concentration of sarcosine in the blood of prostate cancer patients. The final DMFC/biosensor-EC platform showed a colour change perceptible to the naked eye in the presence of increasing sarcosine concentrations. This colour change was controlled by the DMFC operation, making this approach a self-controlled and self-signalling device. Overall, this approach is a proof-of-concept for a fully autonomous biosensor powered by a chemical fuel. This simple and low-cost approach offers the potential to be deployed anywhere and is particularly suitable for point-of-care (POC) analysis.UNINOVA-Instituto de Desenvolvimento de Novas TecnologiasCENIMAT-i3N - Centro de Investigação de Materiais (Lab. Associado I3N)DCM - Departamento de Ciência dos MateriaisRUNFerreira, Nádia S.Carneiro, Liliana P.T.Viezzer, ChristianAlmeida, Maria J. T.Marques, Ana C.Pinto, Alexandra M. F. R.Fortunato, ElviraSales, M. Goreti F.2023-03-15T22:33:25Z2022-10-012022-10-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article9application/pdfhttp://hdl.handle.net/10362/150643eng1572-6657PURE: 55881525https://doi.org/10.1016/j.jelechem.2022.116710info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:32:42Zoai:run.unl.pt:10362/150643Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:54:13.937022Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Passive direct methanol fuel cells acting as fully autonomous electrochemical biosensors
Application to sarcosine detection
title Passive direct methanol fuel cells acting as fully autonomous electrochemical biosensors
spellingShingle Passive direct methanol fuel cells acting as fully autonomous electrochemical biosensors
Ferreira, Nádia S.
Cancer biomarker
Colour display
Electrochromic cell
Molecularly imprinted polymer
Passive direct methanol fuel cell
Sarcosine
Analytical Chemistry
Chemical Engineering(all)
Electrochemistry
SDG 3 - Good Health and Well-being
title_short Passive direct methanol fuel cells acting as fully autonomous electrochemical biosensors
title_full Passive direct methanol fuel cells acting as fully autonomous electrochemical biosensors
title_fullStr Passive direct methanol fuel cells acting as fully autonomous electrochemical biosensors
title_full_unstemmed Passive direct methanol fuel cells acting as fully autonomous electrochemical biosensors
title_sort Passive direct methanol fuel cells acting as fully autonomous electrochemical biosensors
author Ferreira, Nádia S.
author_facet Ferreira, Nádia S.
Carneiro, Liliana P.T.
Viezzer, Christian
Almeida, Maria J. T.
Marques, Ana C.
Pinto, Alexandra M. F. R.
Fortunato, Elvira
Sales, M. Goreti F.
author_role author
author2 Carneiro, Liliana P.T.
Viezzer, Christian
Almeida, Maria J. T.
Marques, Ana C.
Pinto, Alexandra M. F. R.
Fortunato, Elvira
Sales, M. Goreti F.
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv UNINOVA-Instituto de Desenvolvimento de Novas Tecnologias
CENIMAT-i3N - Centro de Investigação de Materiais (Lab. Associado I3N)
DCM - Departamento de Ciência dos Materiais
RUN
dc.contributor.author.fl_str_mv Ferreira, Nádia S.
Carneiro, Liliana P.T.
Viezzer, Christian
Almeida, Maria J. T.
Marques, Ana C.
Pinto, Alexandra M. F. R.
Fortunato, Elvira
Sales, M. Goreti F.
dc.subject.por.fl_str_mv Cancer biomarker
Colour display
Electrochromic cell
Molecularly imprinted polymer
Passive direct methanol fuel cell
Sarcosine
Analytical Chemistry
Chemical Engineering(all)
Electrochemistry
SDG 3 - Good Health and Well-being
topic Cancer biomarker
Colour display
Electrochromic cell
Molecularly imprinted polymer
Passive direct methanol fuel cell
Sarcosine
Analytical Chemistry
Chemical Engineering(all)
Electrochemistry
SDG 3 - Good Health and Well-being
description Publisher Copyright: © 2022 The Author(s)
publishDate 2022
dc.date.none.fl_str_mv 2022-10-01
2022-10-01T00:00:00Z
2023-03-15T22:33:25Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/150643
url http://hdl.handle.net/10362/150643
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 1572-6657
PURE: 55881525
https://doi.org/10.1016/j.jelechem.2022.116710
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 9
application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
_version_ 1799138131841122304

Registros relacionados