Potential causal association between gut microbiome and posttraumatic stress disorder

Detalhes bibliográficos
Autor(a) principal: He, Qiang
Data de Publicação: 2024
Outros Autores: Wang, Wenjing, Xu, Dingkang, Xiong, Yang, Tao, Chuanyuan, You, Chao, Ma, Lu, Ma, Junpeng, Nievergelt, Caroline M., Maihofer, Adam X., Klengel, Torsten, Atkinson, Elizabeth G., Chen, Chia Yen, Choi, Karmel W., Coleman, Jonathan R.I., Dalvie, Shareefa, Duncan, Laramie E., Logue, Mark W., Provost, Allison C., Ratanatharathorn, Andrew, Stein, Murray B., Torres, Katy, Aiello, Allison E., Almli, Lynn M., Amstadter, Ananda B., Andersen, Søren B., Andreassen, Ole A., Arbisi, Paul A., Ashley-Koch, Allison E., Austin, S. Bryn, Avdibegovic, Esmina, Babić, Dragan, Bækvad-Hansen, Marie, Baker, Dewleen G., Beckham, Jean C., Bierut, Laura J., Bisson, Jonathan I., Boks, Marco P., Bolger, Elizabeth A., Børglum, Anders D., Bradley, Bekh, Brashear, Megan, Breen, Gerome, Bryant, Richard A., Bustamante, Angela C., Bybjerg-Grauholm, Jonas, Calabrese, Joseph R., Caldas-de-Almeida, José M., Dale, Anders M., Daly, Mark J., Daskalakis, Nikolaos P., Deckert, Jürgen, Delahanty, Douglas L., Dennis, Michelle F., Disner, Seth G., Domschke, Katharina, Dzubur-Kulenovic, Alma, Erbes, Christopher R., Evans, Alexandra, Farrer, Lindsay A., Feeny, Norah C., Flory, Janine D., Forbes, David, Franz, Carol E., Galea, Sandro, Garrett, Melanie E., Gelaye, Bizu, Gelernter, Joel, Geuze, Elbert, Gillespie, Charles, Uka, Aferdita Goci, Gordon, Scott D., Guffanti, Guia, Hammamieh, Rasha, Harnal, Supriya, Hauser, Michael A., Heath, Andrew C., Hemmings, Sian M.J., Hougaard, David Michael, Jakovljevic, Miro, Jett, Marti, Johnson, Eric Otto, Jones, Ian, Jovanovic, Tanja, Qin, Xue Jun, Junglen, Angela G., Karstoft, Karen Inge, Kaufman, Milissa L., Kessler, Ronald C., Khan, Alaptagin, Kimbrel, Nathan A., King, Anthony P., Koen, Nastassja, Kranzler, Henry R., Kremen, William S., Lawford, Bruce R., Lebois, Lauren A.M., Lewis, Catrin E., Linnstaedt, Sarah D., Lori, Adriana, Lugonja, Bozo, Luykx, Jurjen J., Lyons, Michael J., Maples-Keller, Jessica, Marmar, Charles, Martin, Alicia R., Martin, Nicholas G., Maurer, Douglas, Mavissakalian, Matig R., McFarlane, Alexander, McGlinchey, Regina E., McLaughlin, Katie A., McLean, Samuel A., McLeay, Sarah, Mehta, Divya, Milberg, William P., Miller, Mark W., Morey, Rajendra A., Morris, Charles Phillip, Mors, Ole, Mortensen, Preben B., Neale, Benjamin M., Nelson, Elliot C., Nordentoft, Merete, Norman, Sonya B., O’Donnell, Meaghan, Orcutt, Holly K., Panizzon, Matthew S., Peters, Edward S., Peterson, Alan L., Peverill, Matthew, Pietrzak, Robert H., Polusny, Melissa A., Rice, John P., Ripke, Stephan, Risbrough, Victoria B., Roberts, Andrea L., Rothbaum, Alex O., Rothbaum, Barbara O., Roy-Byrne, Peter, Ruggiero, Ken, Rung, Ariane, Rutten, Bart P.F., Saccone, Nancy L., Sanchez, Sixto E., Schijven, Dick, Seedat, Soraya, Seligowski, Antonia V., Seng, Julia S., Sheerin, Christina M., Silove, Derrick, Smith, Alicia K., Smoller, Jordan W., Solovieff, Nadia, Sponheim, Scott R., Stein, Dan J., Sumner, Jennifer A., Teicher, Martin H., Thompson, Wesley K., Trapido, Edward, Uddin, Monica, Ursano, Robert J., van den Heuvel, Leigh Luella, van Hooff, Miranda, Vermetten, Eric, Vinkers, Christiaan H., Voisey, Joanne, Wang, Yunpeng, Wang, Zhewu, Werge, Thomas, Williams, Michelle A., Williamson, Douglas E., Winternitz, Sherry, Wolf, Christiane, Wolf, Erika J., Wolff, Jonathan D., Yehuda, Rachel, Young, Keith A., Young, Ross Mc D., Zhao, Hongyu, Zoellner, Lori A., Liberzon, Israel, Ressler, Kerry J., Haas, Magali, Koenen, Karestan C.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/163915
Resumo: Funding Information: We thank the participants and working staff including the Psychiatric Genomics Consortium Posttraumatic Stress Disorder Working Group, the FinnGen consortium, and the MiBioGen consortium. Publisher Copyright: © 2024, The Author(s).
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spelling Potential causal association between gut microbiome and posttraumatic stress disorderPsychiatry and Mental healthCellular and Molecular NeuroscienceBiological PsychiatrySDG 3 - Good Health and Well-beingFunding Information: We thank the participants and working staff including the Psychiatric Genomics Consortium Posttraumatic Stress Disorder Working Group, the FinnGen consortium, and the MiBioGen consortium. Publisher Copyright: © 2024, The Author(s).Background: The causal effects of gut microbiome and the development of posttraumatic stress disorder (PTSD) are still unknown. This study aimed to clarify their potential causal association using mendelian randomization (MR). Methods: The summary-level statistics for gut microbiome were retrieved from a genome-wide association study (GWAS) of the MiBioGen consortium. As to PTSD, the Freeze 2 datasets were originated from the Psychiatric Genomics Consortium Posttraumatic Stress Disorder Working Group (PGC-PTSD), and the replicated datasets were obtained from FinnGen consortium. Single nucleotide polymorphisms meeting MR assumptions were selected as instrumental variables. The inverse variance weighting (IVW) method was employed as the main approach, supplemented by sensitivity analyses to evaluate potential pleiotropy and heterogeneity and ensure the robustness of the MR results. We also performed reverse MR analyses to explore PTSD’s causal effects on the relative abundances of specific features of the gut microbiome. Results: In Freeze 2 datasets from PGC-PTSD, eight bacterial traits revealed a potential causal association between gut microbiome and PTSD (IVW, all P < 0.05). In addition, Genus.Dorea and genus.Sellimonas were replicated in FinnGen datasets, in which eight bacterial traits revealed a potential causal association between gut microbiome and the occurrence of PTSD. The heterogeneity and pleiotropy analyses further supported the robustness of the IVW findings, providing additional evidence for their reliability. Conclusion: Our study provides the potential causal impact of gut microbiomes on the development of PTSD, shedding new light on the understanding of the dysfunctional gut-brain axis in this disorder. Our findings present novel evidence and call for investigations to confirm the association between their links, as well as to illuminate the underlying mechanisms.NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)RUNHe, QiangWang, WenjingXu, DingkangXiong, YangTao, ChuanyuanYou, ChaoMa, LuMa, JunpengNievergelt, Caroline M.Maihofer, Adam X.Klengel, TorstenAtkinson, Elizabeth G.Chen, Chia YenChoi, Karmel W.Coleman, Jonathan R.I.Dalvie, ShareefaDuncan, Laramie E.Logue, Mark W.Provost, Allison C.Ratanatharathorn, AndrewStein, Murray B.Torres, KatyAiello, Allison E.Almli, Lynn M.Amstadter, Ananda B.Andersen, Søren B.Andreassen, Ole A.Arbisi, Paul A.Ashley-Koch, Allison E.Austin, S. BrynAvdibegovic, EsminaBabić, DraganBækvad-Hansen, MarieBaker, Dewleen G.Beckham, Jean C.Bierut, Laura J.Bisson, Jonathan I.Boks, Marco P.Bolger, Elizabeth A.Børglum, Anders D.Bradley, BekhBrashear, MeganBreen, GeromeBryant, Richard A.Bustamante, Angela C.Bybjerg-Grauholm, JonasCalabrese, Joseph R.Caldas-de-Almeida, José M.Dale, Anders M.Daly, Mark J.Daskalakis, Nikolaos P.Deckert, JürgenDelahanty, Douglas L.Dennis, Michelle F.Disner, Seth G.Domschke, KatharinaDzubur-Kulenovic, AlmaErbes, Christopher R.Evans, AlexandraFarrer, Lindsay A.Feeny, Norah C.Flory, Janine D.Forbes, DavidFranz, Carol E.Galea, SandroGarrett, Melanie E.Gelaye, BizuGelernter, JoelGeuze, ElbertGillespie, CharlesUka, Aferdita GociGordon, Scott D.Guffanti, GuiaHammamieh, RashaHarnal, SupriyaHauser, Michael A.Heath, Andrew C.Hemmings, Sian M.J.Hougaard, David MichaelJakovljevic, MiroJett, MartiJohnson, Eric OttoJones, IanJovanovic, TanjaQin, Xue JunJunglen, Angela G.Karstoft, Karen IngeKaufman, Milissa L.Kessler, Ronald C.Khan, AlaptaginKimbrel, Nathan A.King, Anthony P.Koen, NastassjaKranzler, Henry R.Kremen, William S.Lawford, Bruce R.Lebois, Lauren A.M.Lewis, Catrin E.Linnstaedt, Sarah D.Lori, AdrianaLugonja, BozoLuykx, Jurjen J.Lyons, Michael J.Maples-Keller, JessicaMarmar, CharlesMartin, Alicia R.Martin, Nicholas G.Maurer, DouglasMavissakalian, Matig R.McFarlane, AlexanderMcGlinchey, Regina E.McLaughlin, Katie A.McLean, Samuel A.McLeay, SarahMehta, DivyaMilberg, William P.Miller, Mark W.Morey, Rajendra A.Morris, Charles PhillipMors, OleMortensen, Preben B.Neale, Benjamin M.Nelson, Elliot C.Nordentoft, MereteNorman, Sonya B.O’Donnell, MeaghanOrcutt, Holly K.Panizzon, Matthew S.Peters, Edward S.Peterson, Alan L.Peverill, MatthewPietrzak, Robert H.Polusny, Melissa A.Rice, John P.Ripke, StephanRisbrough, Victoria B.Roberts, Andrea L.Rothbaum, Alex O.Rothbaum, Barbara O.Roy-Byrne, PeterRuggiero, KenRung, ArianeRutten, Bart P.F.Saccone, Nancy L.Sanchez, Sixto E.Schijven, DickSeedat, SorayaSeligowski, Antonia V.Seng, Julia S.Sheerin, Christina M.Silove, DerrickSmith, Alicia K.Smoller, Jordan W.Solovieff, NadiaSponheim, Scott R.Stein, Dan J.Sumner, Jennifer A.Teicher, Martin H.Thompson, Wesley K.Trapido, EdwardUddin, MonicaUrsano, Robert J.van den Heuvel, Leigh Luellavan Hooff, MirandaVermetten, EricVinkers, Christiaan H.Voisey, JoanneWang, YunpengWang, ZhewuWerge, ThomasWilliams, Michelle A.Williamson, Douglas E.Winternitz, SherryWolf, ChristianeWolf, Erika J.Wolff, Jonathan D.Yehuda, RachelYoung, Keith A.Young, Ross Mc D.Zhao, HongyuZoellner, Lori A.Liberzon, IsraelRessler, Kerry J.Haas, MagaliKoenen, Karestan C.2024-02-22T00:11:40Z2024-01-312024-01-31T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10362/163915eng2158-3188PURE: 83869053https://doi.org/10.1038/s41398-024-02765-7info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:49:34Zoai:run.unl.pt:10362/163915Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:59:55.880788Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Potential causal association between gut microbiome and posttraumatic stress disorder
title Potential causal association between gut microbiome and posttraumatic stress disorder
spellingShingle Potential causal association between gut microbiome and posttraumatic stress disorder
He, Qiang
Psychiatry and Mental health
Cellular and Molecular Neuroscience
Biological Psychiatry
SDG 3 - Good Health and Well-being
title_short Potential causal association between gut microbiome and posttraumatic stress disorder
title_full Potential causal association between gut microbiome and posttraumatic stress disorder
title_fullStr Potential causal association between gut microbiome and posttraumatic stress disorder
title_full_unstemmed Potential causal association between gut microbiome and posttraumatic stress disorder
title_sort Potential causal association between gut microbiome and posttraumatic stress disorder
author He, Qiang
author_facet He, Qiang
Wang, Wenjing
Xu, Dingkang
Xiong, Yang
Tao, Chuanyuan
You, Chao
Ma, Lu
Ma, Junpeng
Nievergelt, Caroline M.
Maihofer, Adam X.
Klengel, Torsten
Atkinson, Elizabeth G.
Chen, Chia Yen
Choi, Karmel W.
Coleman, Jonathan R.I.
Dalvie, Shareefa
Duncan, Laramie E.
Logue, Mark W.
Provost, Allison C.
Ratanatharathorn, Andrew
Stein, Murray B.
Torres, Katy
Aiello, Allison E.
Almli, Lynn M.
Amstadter, Ananda B.
Andersen, Søren B.
Andreassen, Ole A.
Arbisi, Paul A.
Ashley-Koch, Allison E.
Austin, S. Bryn
Avdibegovic, Esmina
Babić, Dragan
Bækvad-Hansen, Marie
Baker, Dewleen G.
Beckham, Jean C.
Bierut, Laura J.
Bisson, Jonathan I.
Boks, Marco P.
Bolger, Elizabeth A.
Børglum, Anders D.
Bradley, Bekh
Brashear, Megan
Breen, Gerome
Bryant, Richard A.
Bustamante, Angela C.
Bybjerg-Grauholm, Jonas
Calabrese, Joseph R.
Caldas-de-Almeida, José M.
Dale, Anders M.
Daly, Mark J.
Daskalakis, Nikolaos P.
Deckert, Jürgen
Delahanty, Douglas L.
Dennis, Michelle F.
Disner, Seth G.
Domschke, Katharina
Dzubur-Kulenovic, Alma
Erbes, Christopher R.
Evans, Alexandra
Farrer, Lindsay A.
Feeny, Norah C.
Flory, Janine D.
Forbes, David
Franz, Carol E.
Galea, Sandro
Garrett, Melanie E.
Gelaye, Bizu
Gelernter, Joel
Geuze, Elbert
Gillespie, Charles
Uka, Aferdita Goci
Gordon, Scott D.
Guffanti, Guia
Hammamieh, Rasha
Harnal, Supriya
Hauser, Michael A.
Heath, Andrew C.
Hemmings, Sian M.J.
Hougaard, David Michael
Jakovljevic, Miro
Jett, Marti
Johnson, Eric Otto
Jones, Ian
Jovanovic, Tanja
Qin, Xue Jun
Junglen, Angela G.
Karstoft, Karen Inge
Kaufman, Milissa L.
Kessler, Ronald C.
Khan, Alaptagin
Kimbrel, Nathan A.
King, Anthony P.
Koen, Nastassja
Kranzler, Henry R.
Kremen, William S.
Lawford, Bruce R.
Lebois, Lauren A.M.
Lewis, Catrin E.
Linnstaedt, Sarah D.
Lori, Adriana
Lugonja, Bozo
Luykx, Jurjen J.
Lyons, Michael J.
Maples-Keller, Jessica
Marmar, Charles
Martin, Alicia R.
Martin, Nicholas G.
Maurer, Douglas
Mavissakalian, Matig R.
McFarlane, Alexander
McGlinchey, Regina E.
McLaughlin, Katie A.
McLean, Samuel A.
McLeay, Sarah
Mehta, Divya
Milberg, William P.
Miller, Mark W.
Morey, Rajendra A.
Morris, Charles Phillip
Mors, Ole
Mortensen, Preben B.
Neale, Benjamin M.
Nelson, Elliot C.
Nordentoft, Merete
Norman, Sonya B.
O’Donnell, Meaghan
Orcutt, Holly K.
Panizzon, Matthew S.
Peters, Edward S.
Peterson, Alan L.
Peverill, Matthew
Pietrzak, Robert H.
Polusny, Melissa A.
Rice, John P.
Ripke, Stephan
Risbrough, Victoria B.
Roberts, Andrea L.
Rothbaum, Alex O.
Rothbaum, Barbara O.
Roy-Byrne, Peter
Ruggiero, Ken
Rung, Ariane
Rutten, Bart P.F.
Saccone, Nancy L.
Sanchez, Sixto E.
Schijven, Dick
Seedat, Soraya
Seligowski, Antonia V.
Seng, Julia S.
Sheerin, Christina M.
Silove, Derrick
Smith, Alicia K.
Smoller, Jordan W.
Solovieff, Nadia
Sponheim, Scott R.
Stein, Dan J.
Sumner, Jennifer A.
Teicher, Martin H.
Thompson, Wesley K.
Trapido, Edward
Uddin, Monica
Ursano, Robert J.
van den Heuvel, Leigh Luella
van Hooff, Miranda
Vermetten, Eric
Vinkers, Christiaan H.
Voisey, Joanne
Wang, Yunpeng
Wang, Zhewu
Werge, Thomas
Williams, Michelle A.
Williamson, Douglas E.
Winternitz, Sherry
Wolf, Christiane
Wolf, Erika J.
Wolff, Jonathan D.
Yehuda, Rachel
Young, Keith A.
Young, Ross Mc D.
Zhao, Hongyu
Zoellner, Lori A.
Liberzon, Israel
Ressler, Kerry J.
Haas, Magali
Koenen, Karestan C.
author_role author
author2 Wang, Wenjing
Xu, Dingkang
Xiong, Yang
Tao, Chuanyuan
You, Chao
Ma, Lu
Ma, Junpeng
Nievergelt, Caroline M.
Maihofer, Adam X.
Klengel, Torsten
Atkinson, Elizabeth G.
Chen, Chia Yen
Choi, Karmel W.
Coleman, Jonathan R.I.
Dalvie, Shareefa
Duncan, Laramie E.
Logue, Mark W.
Provost, Allison C.
Ratanatharathorn, Andrew
Stein, Murray B.
Torres, Katy
Aiello, Allison E.
Almli, Lynn M.
Amstadter, Ananda B.
Andersen, Søren B.
Andreassen, Ole A.
Arbisi, Paul A.
Ashley-Koch, Allison E.
Austin, S. Bryn
Avdibegovic, Esmina
Babić, Dragan
Bækvad-Hansen, Marie
Baker, Dewleen G.
Beckham, Jean C.
Bierut, Laura J.
Bisson, Jonathan I.
Boks, Marco P.
Bolger, Elizabeth A.
Børglum, Anders D.
Bradley, Bekh
Brashear, Megan
Breen, Gerome
Bryant, Richard A.
Bustamante, Angela C.
Bybjerg-Grauholm, Jonas
Calabrese, Joseph R.
Caldas-de-Almeida, José M.
Dale, Anders M.
Daly, Mark J.
Daskalakis, Nikolaos P.
Deckert, Jürgen
Delahanty, Douglas L.
Dennis, Michelle F.
Disner, Seth G.
Domschke, Katharina
Dzubur-Kulenovic, Alma
Erbes, Christopher R.
Evans, Alexandra
Farrer, Lindsay A.
Feeny, Norah C.
Flory, Janine D.
Forbes, David
Franz, Carol E.
Galea, Sandro
Garrett, Melanie E.
Gelaye, Bizu
Gelernter, Joel
Geuze, Elbert
Gillespie, Charles
Uka, Aferdita Goci
Gordon, Scott D.
Guffanti, Guia
Hammamieh, Rasha
Harnal, Supriya
Hauser, Michael A.
Heath, Andrew C.
Hemmings, Sian M.J.
Hougaard, David Michael
Jakovljevic, Miro
Jett, Marti
Johnson, Eric Otto
Jones, Ian
Jovanovic, Tanja
Qin, Xue Jun
Junglen, Angela G.
Karstoft, Karen Inge
Kaufman, Milissa L.
Kessler, Ronald C.
Khan, Alaptagin
Kimbrel, Nathan A.
King, Anthony P.
Koen, Nastassja
Kranzler, Henry R.
Kremen, William S.
Lawford, Bruce R.
Lebois, Lauren A.M.
Lewis, Catrin E.
Linnstaedt, Sarah D.
Lori, Adriana
Lugonja, Bozo
Luykx, Jurjen J.
Lyons, Michael J.
Maples-Keller, Jessica
Marmar, Charles
Martin, Alicia R.
Martin, Nicholas G.
Maurer, Douglas
Mavissakalian, Matig R.
McFarlane, Alexander
McGlinchey, Regina E.
McLaughlin, Katie A.
McLean, Samuel A.
McLeay, Sarah
Mehta, Divya
Milberg, William P.
Miller, Mark W.
Morey, Rajendra A.
Morris, Charles Phillip
Mors, Ole
Mortensen, Preben B.
Neale, Benjamin M.
Nelson, Elliot C.
Nordentoft, Merete
Norman, Sonya B.
O’Donnell, Meaghan
Orcutt, Holly K.
Panizzon, Matthew S.
Peters, Edward S.
Peterson, Alan L.
Peverill, Matthew
Pietrzak, Robert H.
Polusny, Melissa A.
Rice, John P.
Ripke, Stephan
Risbrough, Victoria B.
Roberts, Andrea L.
Rothbaum, Alex O.
Rothbaum, Barbara O.
Roy-Byrne, Peter
Ruggiero, Ken
Rung, Ariane
Rutten, Bart P.F.
Saccone, Nancy L.
Sanchez, Sixto E.
Schijven, Dick
Seedat, Soraya
Seligowski, Antonia V.
Seng, Julia S.
Sheerin, Christina M.
Silove, Derrick
Smith, Alicia K.
Smoller, Jordan W.
Solovieff, Nadia
Sponheim, Scott R.
Stein, Dan J.
Sumner, Jennifer A.
Teicher, Martin H.
Thompson, Wesley K.
Trapido, Edward
Uddin, Monica
Ursano, Robert J.
van den Heuvel, Leigh Luella
van Hooff, Miranda
Vermetten, Eric
Vinkers, Christiaan H.
Voisey, Joanne
Wang, Yunpeng
Wang, Zhewu
Werge, Thomas
Williams, Michelle A.
Williamson, Douglas E.
Winternitz, Sherry
Wolf, Christiane
Wolf, Erika J.
Wolff, Jonathan D.
Yehuda, Rachel
Young, Keith A.
Young, Ross Mc D.
Zhao, Hongyu
Zoellner, Lori A.
Liberzon, Israel
Ressler, Kerry J.
Haas, Magali
Koenen, Karestan C.
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dc.contributor.none.fl_str_mv NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
RUN
dc.contributor.author.fl_str_mv He, Qiang
Wang, Wenjing
Xu, Dingkang
Xiong, Yang
Tao, Chuanyuan
You, Chao
Ma, Lu
Ma, Junpeng
Nievergelt, Caroline M.
Maihofer, Adam X.
Klengel, Torsten
Atkinson, Elizabeth G.
Chen, Chia Yen
Choi, Karmel W.
Coleman, Jonathan R.I.
Dalvie, Shareefa
Duncan, Laramie E.
Logue, Mark W.
Provost, Allison C.
Ratanatharathorn, Andrew
Stein, Murray B.
Torres, Katy
Aiello, Allison E.
Almli, Lynn M.
Amstadter, Ananda B.
Andersen, Søren B.
Andreassen, Ole A.
Arbisi, Paul A.
Ashley-Koch, Allison E.
Austin, S. Bryn
Avdibegovic, Esmina
Babić, Dragan
Bækvad-Hansen, Marie
Baker, Dewleen G.
Beckham, Jean C.
Bierut, Laura J.
Bisson, Jonathan I.
Boks, Marco P.
Bolger, Elizabeth A.
Børglum, Anders D.
Bradley, Bekh
Brashear, Megan
Breen, Gerome
Bryant, Richard A.
Bustamante, Angela C.
Bybjerg-Grauholm, Jonas
Calabrese, Joseph R.
Caldas-de-Almeida, José M.
Dale, Anders M.
Daly, Mark J.
Daskalakis, Nikolaos P.
Deckert, Jürgen
Delahanty, Douglas L.
Dennis, Michelle F.
Disner, Seth G.
Domschke, Katharina
Dzubur-Kulenovic, Alma
Erbes, Christopher R.
Evans, Alexandra
Farrer, Lindsay A.
Feeny, Norah C.
Flory, Janine D.
Forbes, David
Franz, Carol E.
Galea, Sandro
Garrett, Melanie E.
Gelaye, Bizu
Gelernter, Joel
Geuze, Elbert
Gillespie, Charles
Uka, Aferdita Goci
Gordon, Scott D.
Guffanti, Guia
Hammamieh, Rasha
Harnal, Supriya
Hauser, Michael A.
Heath, Andrew C.
Hemmings, Sian M.J.
Hougaard, David Michael
Jakovljevic, Miro
Jett, Marti
Johnson, Eric Otto
Jones, Ian
Jovanovic, Tanja
Qin, Xue Jun
Junglen, Angela G.
Karstoft, Karen Inge
Kaufman, Milissa L.
Kessler, Ronald C.
Khan, Alaptagin
Kimbrel, Nathan A.
King, Anthony P.
Koen, Nastassja
Kranzler, Henry R.
Kremen, William S.
Lawford, Bruce R.
Lebois, Lauren A.M.
Lewis, Catrin E.
Linnstaedt, Sarah D.
Lori, Adriana
Lugonja, Bozo
Luykx, Jurjen J.
Lyons, Michael J.
Maples-Keller, Jessica
Marmar, Charles
Martin, Alicia R.
Martin, Nicholas G.
Maurer, Douglas
Mavissakalian, Matig R.
McFarlane, Alexander
McGlinchey, Regina E.
McLaughlin, Katie A.
McLean, Samuel A.
McLeay, Sarah
Mehta, Divya
Milberg, William P.
Miller, Mark W.
Morey, Rajendra A.
Morris, Charles Phillip
Mors, Ole
Mortensen, Preben B.
Neale, Benjamin M.
Nelson, Elliot C.
Nordentoft, Merete
Norman, Sonya B.
O’Donnell, Meaghan
Orcutt, Holly K.
Panizzon, Matthew S.
Peters, Edward S.
Peterson, Alan L.
Peverill, Matthew
Pietrzak, Robert H.
Polusny, Melissa A.
Rice, John P.
Ripke, Stephan
Risbrough, Victoria B.
Roberts, Andrea L.
Rothbaum, Alex O.
Rothbaum, Barbara O.
Roy-Byrne, Peter
Ruggiero, Ken
Rung, Ariane
Rutten, Bart P.F.
Saccone, Nancy L.
Sanchez, Sixto E.
Schijven, Dick
Seedat, Soraya
Seligowski, Antonia V.
Seng, Julia S.
Sheerin, Christina M.
Silove, Derrick
Smith, Alicia K.
Smoller, Jordan W.
Solovieff, Nadia
Sponheim, Scott R.
Stein, Dan J.
Sumner, Jennifer A.
Teicher, Martin H.
Thompson, Wesley K.
Trapido, Edward
Uddin, Monica
Ursano, Robert J.
van den Heuvel, Leigh Luella
van Hooff, Miranda
Vermetten, Eric
Vinkers, Christiaan H.
Voisey, Joanne
Wang, Yunpeng
Wang, Zhewu
Werge, Thomas
Williams, Michelle A.
Williamson, Douglas E.
Winternitz, Sherry
Wolf, Christiane
Wolf, Erika J.
Wolff, Jonathan D.
Yehuda, Rachel
Young, Keith A.
Young, Ross Mc D.
Zhao, Hongyu
Zoellner, Lori A.
Liberzon, Israel
Ressler, Kerry J.
Haas, Magali
Koenen, Karestan C.
dc.subject.por.fl_str_mv Psychiatry and Mental health
Cellular and Molecular Neuroscience
Biological Psychiatry
SDG 3 - Good Health and Well-being
topic Psychiatry and Mental health
Cellular and Molecular Neuroscience
Biological Psychiatry
SDG 3 - Good Health and Well-being
description Funding Information: We thank the participants and working staff including the Psychiatric Genomics Consortium Posttraumatic Stress Disorder Working Group, the FinnGen consortium, and the MiBioGen consortium. Publisher Copyright: © 2024, The Author(s).
publishDate 2024
dc.date.none.fl_str_mv 2024-02-22T00:11:40Z
2024-01-31
2024-01-31T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/163915
url http://hdl.handle.net/10362/163915
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 2158-3188
PURE: 83869053
https://doi.org/10.1038/s41398-024-02765-7
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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