Proving the suitability of magnetoelectric stimuli for tissue engineering applications

Detalhes bibliográficos
Autor(a) principal: Ribeiro, C.
Data de Publicação: 2016
Outros Autores: Correia, Vítor Manuel Gomes, Martins, P., Gama, F. M., Lanceros-Méndez, S.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/1822/40151
Resumo: A novel approach for tissue engineering applications based on the use of magnetoelectric materials is presented. This work proves that magnetoelectric Terfenol-D/poly(vinylidene fluoride-co-trifluoroethylene) composites are able to provide mechanical and electrical stimuli to MC3T3-E1 pre-osteoblast cells and that those stimuli can be remotely triggered by an applied magnetic field. Cell proliferation is enhanced up to 25% when cells are cultured under mechanical (up to 110 ppm) and electrical stimulation (up to 0.115 mV), showing that magnetoelectric cell stimulation is a novel and suitable approach for tissue engineering allowing magnetic, mechanical and electrical stimuli.
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spelling Proving the suitability of magnetoelectric stimuli for tissue engineering applicationsBone tissue engineeringCell proliferationMagnetic stimulusMagnetoelectricScience & TechnologyA novel approach for tissue engineering applications based on the use of magnetoelectric materials is presented. This work proves that magnetoelectric Terfenol-D/poly(vinylidene fluoride-co-trifluoroethylene) composites are able to provide mechanical and electrical stimuli to MC3T3-E1 pre-osteoblast cells and that those stimuli can be remotely triggered by an applied magnetic field. Cell proliferation is enhanced up to 25% when cells are cultured under mechanical (up to 110 ppm) and electrical stimulation (up to 0.115 mV), showing that magnetoelectric cell stimulation is a novel and suitable approach for tissue engineering allowing magnetic, mechanical and electrical stimuli.This work is funded by FEDER funds through the “Programa Operacional Fatores de Competitividade—COMPETE” and by national funds arranged by FCT—Fundac¸ ão para a Ciência e a Tecnologia, project reference PEST-C/FIS/UI607/2014. C.R., V.C. and P.M. thank the FCT for the SFRH/BPD/90870/2012, SFRH/BPD/96227/2013 and SFRH/BPD/97739/2013 grants, respectively. The authors thank financial support from the Basque Government Industry Department under the ELKARTEK Program. S.L.M. thanks the Diputación de Bizkaia for financial support under the Bizkaia Talent program.Elsevier B.V.Universidade do MinhoRibeiro, C.Correia, Vítor Manuel GomesMartins, P.Gama, F. M.Lanceros-Méndez, S.2016-042016-04-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/40151engRibeiro, C.; Correia, V.; Martins, P.; Gama, F. M.; Lanceros-Mendez, S., Proving the suitability of magnetoelectric stimuli for tissue engineering applications. Colloids and Surfaces B: Biointerfaces, 140, 430-436, 20160927-77650927-776510.1016/j.colsurfb.2015.12.05526797659http://www.journals.elsevier.com/colloids-and-surfaces-b-biointerfaces/info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:28:12Zoai:repositorium.sdum.uminho.pt:1822/40151Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T19:22:58.092586Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Proving the suitability of magnetoelectric stimuli for tissue engineering applications
title Proving the suitability of magnetoelectric stimuli for tissue engineering applications
spellingShingle Proving the suitability of magnetoelectric stimuli for tissue engineering applications
Ribeiro, C.
Bone tissue engineering
Cell proliferation
Magnetic stimulus
Magnetoelectric
Science & Technology
title_short Proving the suitability of magnetoelectric stimuli for tissue engineering applications
title_full Proving the suitability of magnetoelectric stimuli for tissue engineering applications
title_fullStr Proving the suitability of magnetoelectric stimuli for tissue engineering applications
title_full_unstemmed Proving the suitability of magnetoelectric stimuli for tissue engineering applications
title_sort Proving the suitability of magnetoelectric stimuli for tissue engineering applications
author Ribeiro, C.
author_facet Ribeiro, C.
Correia, Vítor Manuel Gomes
Martins, P.
Gama, F. M.
Lanceros-Méndez, S.
author_role author
author2 Correia, Vítor Manuel Gomes
Martins, P.
Gama, F. M.
Lanceros-Méndez, S.
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Universidade do Minho
dc.contributor.author.fl_str_mv Ribeiro, C.
Correia, Vítor Manuel Gomes
Martins, P.
Gama, F. M.
Lanceros-Méndez, S.
dc.subject.por.fl_str_mv Bone tissue engineering
Cell proliferation
Magnetic stimulus
Magnetoelectric
Science & Technology
topic Bone tissue engineering
Cell proliferation
Magnetic stimulus
Magnetoelectric
Science & Technology
description A novel approach for tissue engineering applications based on the use of magnetoelectric materials is presented. This work proves that magnetoelectric Terfenol-D/poly(vinylidene fluoride-co-trifluoroethylene) composites are able to provide mechanical and electrical stimuli to MC3T3-E1 pre-osteoblast cells and that those stimuli can be remotely triggered by an applied magnetic field. Cell proliferation is enhanced up to 25% when cells are cultured under mechanical (up to 110 ppm) and electrical stimulation (up to 0.115 mV), showing that magnetoelectric cell stimulation is a novel and suitable approach for tissue engineering allowing magnetic, mechanical and electrical stimuli.
publishDate 2016
dc.date.none.fl_str_mv 2016-04
2016-04-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/1822/40151
url http://hdl.handle.net/1822/40151
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Ribeiro, C.; Correia, V.; Martins, P.; Gama, F. M.; Lanceros-Mendez, S., Proving the suitability of magnetoelectric stimuli for tissue engineering applications. Colloids and Surfaces B: Biointerfaces, 140, 430-436, 2016
0927-7765
0927-7765
10.1016/j.colsurfb.2015.12.055
26797659
http://www.journals.elsevier.com/colloids-and-surfaces-b-biointerfaces/
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier B.V.
publisher.none.fl_str_mv Elsevier B.V.
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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