Omalizumab induced Takotsubo syndrome : case report

Detalhes bibliográficos
Autor(a) principal: Aguiar-Ricardo, Inês
Data de Publicação: 2019
Outros Autores: Nunes-Ferreira, Afonso, Roda, Ângela, Rosario, Luis
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10451/40043
Resumo: © The Author(s) 2019.The Author(s) 2019. Published by Oxford University Press on behalf of the European Society of Cardiology. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
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spelling Omalizumab induced Takotsubo syndrome : case reportTakotsubo syndromeOmalizumabCase reportLeft ventricular dysfunction© The Author(s) 2019.The Author(s) 2019. Published by Oxford University Press on behalf of the European Society of Cardiology. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.comBackground: Omalizumab is a humanized monoclonal anti-immunoglobulin E antibody, approved for the treatment of spontaneous chronic urticaria, with high efficacy and an excellent safety profile. Although its adverse effects are rare, allergic reactions and cardiovascular events were previously described. Case summary: The authors describe the case of a 75-year-old woman, followed at the outpatient dermatology clinic due to spontaneous chronic urticaria, treated with omalizumab 300 mg every 4 weeks. After the 11th administration of omalizumab, the patient developed an episode of thoracalgia associated with electro- and echocardiographic abnormalities. Coronary angiogram excluded coronary artery disease, and left ventriculography demonstrated mid-apical akinesia and basal hyperkinesia, consistent with the Takotsubo syndrome (TS). Discussion: Takotsubo syndrome was already reported in association with other monoclonal antibodies. However, to our knowledge, this is the first case of TS following the administration of omalizumab.Oxford University PressRepositório da Universidade de LisboaAguiar-Ricardo, InêsNunes-Ferreira, AfonsoRoda, ÂngelaRosario, Luis2019-11-04T15:57:54Z20192019-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/40043engEuropean Heart Journal - Case Reports, Volume 3, Issue 1, March 2019, yty1552514-211910.1093/ehjcr/yty155info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-08T16:39:05Zoai:repositorio.ul.pt:10451/40043Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T21:53:46.022895Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Omalizumab induced Takotsubo syndrome : case report
title Omalizumab induced Takotsubo syndrome : case report
spellingShingle Omalizumab induced Takotsubo syndrome : case report
Aguiar-Ricardo, Inês
Takotsubo syndrome
Omalizumab
Case report
Left ventricular dysfunction
title_short Omalizumab induced Takotsubo syndrome : case report
title_full Omalizumab induced Takotsubo syndrome : case report
title_fullStr Omalizumab induced Takotsubo syndrome : case report
title_full_unstemmed Omalizumab induced Takotsubo syndrome : case report
title_sort Omalizumab induced Takotsubo syndrome : case report
author Aguiar-Ricardo, Inês
author_facet Aguiar-Ricardo, Inês
Nunes-Ferreira, Afonso
Roda, Ângela
Rosario, Luis
author_role author
author2 Nunes-Ferreira, Afonso
Roda, Ângela
Rosario, Luis
author2_role author
author
author
dc.contributor.none.fl_str_mv Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv Aguiar-Ricardo, Inês
Nunes-Ferreira, Afonso
Roda, Ângela
Rosario, Luis
dc.subject.por.fl_str_mv Takotsubo syndrome
Omalizumab
Case report
Left ventricular dysfunction
topic Takotsubo syndrome
Omalizumab
Case report
Left ventricular dysfunction
description © The Author(s) 2019.The Author(s) 2019. Published by Oxford University Press on behalf of the European Society of Cardiology. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
publishDate 2019
dc.date.none.fl_str_mv 2019-11-04T15:57:54Z
2019
2019-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10451/40043
url http://hdl.handle.net/10451/40043
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv European Heart Journal - Case Reports, Volume 3, Issue 1, March 2019, yty155
2514-2119
10.1093/ehjcr/yty155
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Oxford University Press
publisher.none.fl_str_mv Oxford University Press
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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