Poly(Thionine)-Modified Screen-Printed Electrodes for CA 19-9 Detection and Its Properties in Raman Spectroscopy

Detalhes bibliográficos
Autor(a) principal: Castaño-Guerrero, Yuselis
Data de Publicação: 2022
Outros Autores: Romaguera-Barcelay, Yonny, Moreira, Felismina Teixeira Coelho, Brito, Walter Ricardo, Fortunato, Elvira, Sales, Maria Goreti Ferreira
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/143551
Resumo: Funding Information: Funding: This research was funded by Fundação para a Ciência e Tecnologia grant number SFRH/BD /145590/2019. Funding Information: Acknowledgments: Y.C.-G. acknowledges the PhD grant reference SFRH/BD/145590/2019 to Fundação para a Ciência e Tecnologia. Publisher Copyright: © 2022 by the authors. Licensee MDPI, Basel, Switzerland.
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spelling Poly(Thionine)-Modified Screen-Printed Electrodes for CA 19-9 Detection and Its Properties in Raman SpectroscopyCA 19-9Cancer biomarkerElectrochemistryScreen-printed electrodesSERSThionineAnalytical ChemistryPhysical and Theoretical ChemistrySDG 3 - Good Health and Well-beingFunding Information: Funding: This research was funded by Fundação para a Ciência e Tecnologia grant number SFRH/BD /145590/2019. Funding Information: Acknowledgments: Y.C.-G. acknowledges the PhD grant reference SFRH/BD/145590/2019 to Fundação para a Ciência e Tecnologia. Publisher Copyright: © 2022 by the authors. Licensee MDPI, Basel, Switzerland.Polythionine (PTH) is an electroactive compound known for its excellent electron transfer capacity. It has stable and redox centers in its structure, and it can also be generated by electropoly-merization of thionine (TH). Due to its properties, it has been used in a large number of applications, including the construction of electrochemical biosensors. In this work, PTH is explored for its ability to generate electrons, which allows it to act as an electrochemical probe in a biosensor that detects CA 19-9 on two different substrates, carbon and gold, using differential pulse voltammetry (DPV) as a reading technique in phosphate buffer (PhB). The analytical features of the resulting electrodes are given, showing linear ranges from 0.010 to 10 U/mL. The Raman spectra of PTH films on gold (substrates or nanostars) and carbon (substrates) are also presented and discussed as a potential use for SERS readings as complementary information to electrochemical data.UNINOVA-Instituto de Desenvolvimento de Novas TecnologiasCENIMAT-i3N - Centro de Investigação de Materiais (Lab. Associado I3N)DCM - Departamento de Ciência dos MateriaisRUNCastaño-Guerrero, YuselisRomaguera-Barcelay, YonnyMoreira, Felismina Teixeira CoelhoBrito, Walter RicardoFortunato, ElviraSales, Maria Goreti Ferreira2022-09-06T22:42:35Z2022-02-272022-02-27T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article14application/pdfhttp://hdl.handle.net/10362/143551eng2227-9040PURE: 46292930https://doi.org/10.3390/chemosensors10030092info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:21:59Zoai:run.unl.pt:10362/143551Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:51:00.595655Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Poly(Thionine)-Modified Screen-Printed Electrodes for CA 19-9 Detection and Its Properties in Raman Spectroscopy
title Poly(Thionine)-Modified Screen-Printed Electrodes for CA 19-9 Detection and Its Properties in Raman Spectroscopy
spellingShingle Poly(Thionine)-Modified Screen-Printed Electrodes for CA 19-9 Detection and Its Properties in Raman Spectroscopy
Castaño-Guerrero, Yuselis
CA 19-9
Cancer biomarker
Electrochemistry
Screen-printed electrodes
SERS
Thionine
Analytical Chemistry
Physical and Theoretical Chemistry
SDG 3 - Good Health and Well-being
title_short Poly(Thionine)-Modified Screen-Printed Electrodes for CA 19-9 Detection and Its Properties in Raman Spectroscopy
title_full Poly(Thionine)-Modified Screen-Printed Electrodes for CA 19-9 Detection and Its Properties in Raman Spectroscopy
title_fullStr Poly(Thionine)-Modified Screen-Printed Electrodes for CA 19-9 Detection and Its Properties in Raman Spectroscopy
title_full_unstemmed Poly(Thionine)-Modified Screen-Printed Electrodes for CA 19-9 Detection and Its Properties in Raman Spectroscopy
title_sort Poly(Thionine)-Modified Screen-Printed Electrodes for CA 19-9 Detection and Its Properties in Raman Spectroscopy
author Castaño-Guerrero, Yuselis
author_facet Castaño-Guerrero, Yuselis
Romaguera-Barcelay, Yonny
Moreira, Felismina Teixeira Coelho
Brito, Walter Ricardo
Fortunato, Elvira
Sales, Maria Goreti Ferreira
author_role author
author2 Romaguera-Barcelay, Yonny
Moreira, Felismina Teixeira Coelho
Brito, Walter Ricardo
Fortunato, Elvira
Sales, Maria Goreti Ferreira
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv UNINOVA-Instituto de Desenvolvimento de Novas Tecnologias
CENIMAT-i3N - Centro de Investigação de Materiais (Lab. Associado I3N)
DCM - Departamento de Ciência dos Materiais
RUN
dc.contributor.author.fl_str_mv Castaño-Guerrero, Yuselis
Romaguera-Barcelay, Yonny
Moreira, Felismina Teixeira Coelho
Brito, Walter Ricardo
Fortunato, Elvira
Sales, Maria Goreti Ferreira
dc.subject.por.fl_str_mv CA 19-9
Cancer biomarker
Electrochemistry
Screen-printed electrodes
SERS
Thionine
Analytical Chemistry
Physical and Theoretical Chemistry
SDG 3 - Good Health and Well-being
topic CA 19-9
Cancer biomarker
Electrochemistry
Screen-printed electrodes
SERS
Thionine
Analytical Chemistry
Physical and Theoretical Chemistry
SDG 3 - Good Health and Well-being
description Funding Information: Funding: This research was funded by Fundação para a Ciência e Tecnologia grant number SFRH/BD /145590/2019. Funding Information: Acknowledgments: Y.C.-G. acknowledges the PhD grant reference SFRH/BD/145590/2019 to Fundação para a Ciência e Tecnologia. Publisher Copyright: © 2022 by the authors. Licensee MDPI, Basel, Switzerland.
publishDate 2022
dc.date.none.fl_str_mv 2022-09-06T22:42:35Z
2022-02-27
2022-02-27T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/143551
url http://hdl.handle.net/10362/143551
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 2227-9040
PURE: 46292930
https://doi.org/10.3390/chemosensors10030092
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 14
application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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