Q Fever: an Emerging Reality in Portugal

Detalhes bibliográficos
Autor(a) principal: Lencastre Monteiro, R
Data de Publicação: 2021
Outros Autores: Nascimento, R, Diogo, J, Bernardino, R, Leão, R
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.17/3927
Resumo: Q fever is a zoonosis caused by Coxiella burnetii with worldwide distribution at the increasing expression in Europe and endemic in Portugal. It is transmitted by inhalation of aerosols containing spores, main reservoir being cattle, goats and sheep as by ingesting cottage cheese or unpasteurized milk. The majority of patients are asymptomatic; however, they may present with fever, atypical pneumonia, acute hepatitis, cutaneous manifestations and rarely with cardiac or neurological involvement. Although most cases are self-limited, focal persistent or chronic Q fever can manifest years after the onset, wherefore follow-up is essential. The clinical heterogeneity may be so variable that the disease is often diagnosed only if it has been systematically considered. It should be especially taken into account in the presence of risk factors as valvular or joint prostheses, immunocompromised patients, pregnant women and epidemiological setting. The authors present a rare case of Coxiella burnetii pneumonia with cutaneous and hepatic manifestations without any risk factor. This case aims to emphasize the importance of Q fever in the differential diagnosis of fever or atypical pneumonia, even in the absence of known risk factors. The diagnosis is often challenging for clinicians and it is necessary to maintain a high index of suspicion. In Europe and specifically in Portugal is mandatory to report the cases to establish the real impact of this disease.
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spelling Q Fever: an Emerging Reality in PortugalHSAC MEDPortugalQ FeverAtypical PneumoniaCoxiella BurnetiiEndemicQ fever is a zoonosis caused by Coxiella burnetii with worldwide distribution at the increasing expression in Europe and endemic in Portugal. It is transmitted by inhalation of aerosols containing spores, main reservoir being cattle, goats and sheep as by ingesting cottage cheese or unpasteurized milk. The majority of patients are asymptomatic; however, they may present with fever, atypical pneumonia, acute hepatitis, cutaneous manifestations and rarely with cardiac or neurological involvement. Although most cases are self-limited, focal persistent or chronic Q fever can manifest years after the onset, wherefore follow-up is essential. The clinical heterogeneity may be so variable that the disease is often diagnosed only if it has been systematically considered. It should be especially taken into account in the presence of risk factors as valvular or joint prostheses, immunocompromised patients, pregnant women and epidemiological setting. The authors present a rare case of Coxiella burnetii pneumonia with cutaneous and hepatic manifestations without any risk factor. This case aims to emphasize the importance of Q fever in the differential diagnosis of fever or atypical pneumonia, even in the absence of known risk factors. The diagnosis is often challenging for clinicians and it is necessary to maintain a high index of suspicion. In Europe and specifically in Portugal is mandatory to report the cases to establish the real impact of this disease.Repositório do Centro Hospitalar Universitário de Lisboa Central, EPELencastre Monteiro, RNascimento, RDiogo, JBernardino, RLeão, R2021-12-03T16:11:08Z20212021-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.17/3927engCureus. 2021 Oct 25;13(10):e19018.10.7759/cureus.19018.info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-03-10T09:44:38Zoai:repositorio.chlc.min-saude.pt:10400.17/3927Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T17:21:14.151088Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Q Fever: an Emerging Reality in Portugal
title Q Fever: an Emerging Reality in Portugal
spellingShingle Q Fever: an Emerging Reality in Portugal
Lencastre Monteiro, R
HSAC MED
Portugal
Q Fever
Atypical Pneumonia
Coxiella Burnetii
Endemic
title_short Q Fever: an Emerging Reality in Portugal
title_full Q Fever: an Emerging Reality in Portugal
title_fullStr Q Fever: an Emerging Reality in Portugal
title_full_unstemmed Q Fever: an Emerging Reality in Portugal
title_sort Q Fever: an Emerging Reality in Portugal
author Lencastre Monteiro, R
author_facet Lencastre Monteiro, R
Nascimento, R
Diogo, J
Bernardino, R
Leão, R
author_role author
author2 Nascimento, R
Diogo, J
Bernardino, R
Leão, R
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Repositório do Centro Hospitalar Universitário de Lisboa Central, EPE
dc.contributor.author.fl_str_mv Lencastre Monteiro, R
Nascimento, R
Diogo, J
Bernardino, R
Leão, R
dc.subject.por.fl_str_mv HSAC MED
Portugal
Q Fever
Atypical Pneumonia
Coxiella Burnetii
Endemic
topic HSAC MED
Portugal
Q Fever
Atypical Pneumonia
Coxiella Burnetii
Endemic
description Q fever is a zoonosis caused by Coxiella burnetii with worldwide distribution at the increasing expression in Europe and endemic in Portugal. It is transmitted by inhalation of aerosols containing spores, main reservoir being cattle, goats and sheep as by ingesting cottage cheese or unpasteurized milk. The majority of patients are asymptomatic; however, they may present with fever, atypical pneumonia, acute hepatitis, cutaneous manifestations and rarely with cardiac or neurological involvement. Although most cases are self-limited, focal persistent or chronic Q fever can manifest years after the onset, wherefore follow-up is essential. The clinical heterogeneity may be so variable that the disease is often diagnosed only if it has been systematically considered. It should be especially taken into account in the presence of risk factors as valvular or joint prostheses, immunocompromised patients, pregnant women and epidemiological setting. The authors present a rare case of Coxiella burnetii pneumonia with cutaneous and hepatic manifestations without any risk factor. This case aims to emphasize the importance of Q fever in the differential diagnosis of fever or atypical pneumonia, even in the absence of known risk factors. The diagnosis is often challenging for clinicians and it is necessary to maintain a high index of suspicion. In Europe and specifically in Portugal is mandatory to report the cases to establish the real impact of this disease.
publishDate 2021
dc.date.none.fl_str_mv 2021-12-03T16:11:08Z
2021
2021-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.17/3927
url http://hdl.handle.net/10400.17/3927
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Cureus. 2021 Oct 25;13(10):e19018.
10.7759/cureus.19018.
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eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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instacron:RCAAP
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