Lucio's Phenomenon: Response to Alternative Treatment with Multibacilar Polychemotherapy
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://doi.org/10.29021/spdv.76.2.804 |
Resumo: | Leprosy is an infectious disease of chronic evolution caused by Mycobacterium leprae. Its chronic course can be interrupted by acute or subacute reactional episodes. Lucius phenomenon is a vasculitic immune reaction that occurs in patients with lepromatous leprosy. It appears with purpuric macules that progress to ascending necrosis and ulceration and heal with an atrophic scar. The authors describe the case of a 73-year-old male patient with ulceronecrotic lesions in the lower limbs and tendinous calcaneal exposure. Clinical-laboratory data and dermatological examination confirmed the diagnosis of lepromatous leprosy with vasculitis of the Lucius-like type. It progressed with a good response to the alternative treatment with multibacillary multidrug therapy. |
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Lucio's Phenomenon: Response to Alternative Treatment with Multibacilar PolychemotherapyFenómeno de Lúcio: Resposta ao Tratamento Alternativo com Poliquimioterapia MultibacilarDrug TherapyCombinationLeprosyLepromatousMycobacterium lepraeLepra LepromatosaMycobacterium lepraeQuimioterapia CombinadaLeprosy is an infectious disease of chronic evolution caused by Mycobacterium leprae. Its chronic course can be interrupted by acute or subacute reactional episodes. Lucius phenomenon is a vasculitic immune reaction that occurs in patients with lepromatous leprosy. It appears with purpuric macules that progress to ascending necrosis and ulceration and heal with an atrophic scar. The authors describe the case of a 73-year-old male patient with ulceronecrotic lesions in the lower limbs and tendinous calcaneal exposure. Clinical-laboratory data and dermatological examination confirmed the diagnosis of lepromatous leprosy with vasculitis of the Lucius-like type. It progressed with a good response to the alternative treatment with multibacillary multidrug therapy.A hanseníase é uma doença infectocontagiosa de evolução crónica, causada pelo Mycobacterium leprae. Seu curso crónico pode ser interrompido por episódios reacionais agudos ou subagudos. O fenómeno de Lúcio é uma reação imunológica vasculítica que ocorre em doentes com lepra lepromatosa. Surge com máculas purpúricas que evoluem com necrose e ulceração, de forma ascendente, deixando cicatriz atrófica. Os autores descrevem o caso de um paciente de 73 anos, sexo masculino, com lesões ulceronecróticas em membros inferiores e exposição tendinosa em calcâneo. Com base em dados clínico-laboratoriais e exame dermatológico, confirmado diagnóstico de lepra lepromatosa com vasculite do tipo fenómeno de Lúcio. Evoluiu com boa resposta ao esquema alternativo de tratamento com poliquimioterapia multibacilar.Sociedade Portuguesa de Dermatologia e Venereologia2018-05-29T00:00:00Zjournal articleinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://doi.org/10.29021/spdv.76.2.804oai:ojs.revista.spdv.com.pt:article/804Journal of the Portuguese Society of Dermatology and Venereology; Vol 76 No 2 (2018): April - June; 185-188Revista da Sociedade Portuguesa de Dermatologia e Venereologia; v. 76 n. 2 (2018): Abril - Junho; 185-1882182-24092182-2395reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://revista.spdv.com.pt/index.php/spdv/article/view/804https://doi.org/10.29021/spdv.76.2.804https://revista.spdv.com.pt/index.php/spdv/article/view/804/569Araujo Dantas, CamilaMedeiros Prohmann, CarolineBarcelos e Silva, LorenaFigueiredo Gatti, RafaelMarçal Machado, ThalitaCordeiro Soubhia, Rosa MariaAntonio, João Robertoinfo:eu-repo/semantics/openAccess2022-10-06T12:35:04Zoai:ojs.revista.spdv.com.pt:article/804Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:11:03.231135Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Lucio's Phenomenon: Response to Alternative Treatment with Multibacilar Polychemotherapy Fenómeno de Lúcio: Resposta ao Tratamento Alternativo com Poliquimioterapia Multibacilar |
title |
Lucio's Phenomenon: Response to Alternative Treatment with Multibacilar Polychemotherapy |
spellingShingle |
Lucio's Phenomenon: Response to Alternative Treatment with Multibacilar Polychemotherapy Araujo Dantas, Camila Drug Therapy Combination Leprosy Lepromatous Mycobacterium leprae Lepra Lepromatosa Mycobacterium leprae Quimioterapia Combinada |
title_short |
Lucio's Phenomenon: Response to Alternative Treatment with Multibacilar Polychemotherapy |
title_full |
Lucio's Phenomenon: Response to Alternative Treatment with Multibacilar Polychemotherapy |
title_fullStr |
Lucio's Phenomenon: Response to Alternative Treatment with Multibacilar Polychemotherapy |
title_full_unstemmed |
Lucio's Phenomenon: Response to Alternative Treatment with Multibacilar Polychemotherapy |
title_sort |
Lucio's Phenomenon: Response to Alternative Treatment with Multibacilar Polychemotherapy |
author |
Araujo Dantas, Camila |
author_facet |
Araujo Dantas, Camila Medeiros Prohmann, Caroline Barcelos e Silva, Lorena Figueiredo Gatti, Rafael Marçal Machado, Thalita Cordeiro Soubhia, Rosa Maria Antonio, João Roberto |
author_role |
author |
author2 |
Medeiros Prohmann, Caroline Barcelos e Silva, Lorena Figueiredo Gatti, Rafael Marçal Machado, Thalita Cordeiro Soubhia, Rosa Maria Antonio, João Roberto |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Araujo Dantas, Camila Medeiros Prohmann, Caroline Barcelos e Silva, Lorena Figueiredo Gatti, Rafael Marçal Machado, Thalita Cordeiro Soubhia, Rosa Maria Antonio, João Roberto |
dc.subject.por.fl_str_mv |
Drug Therapy Combination Leprosy Lepromatous Mycobacterium leprae Lepra Lepromatosa Mycobacterium leprae Quimioterapia Combinada |
topic |
Drug Therapy Combination Leprosy Lepromatous Mycobacterium leprae Lepra Lepromatosa Mycobacterium leprae Quimioterapia Combinada |
description |
Leprosy is an infectious disease of chronic evolution caused by Mycobacterium leprae. Its chronic course can be interrupted by acute or subacute reactional episodes. Lucius phenomenon is a vasculitic immune reaction that occurs in patients with lepromatous leprosy. It appears with purpuric macules that progress to ascending necrosis and ulceration and heal with an atrophic scar. The authors describe the case of a 73-year-old male patient with ulceronecrotic lesions in the lower limbs and tendinous calcaneal exposure. Clinical-laboratory data and dermatological examination confirmed the diagnosis of lepromatous leprosy with vasculitis of the Lucius-like type. It progressed with a good response to the alternative treatment with multibacillary multidrug therapy. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-05-29T00:00:00Z |
dc.type.driver.fl_str_mv |
journal article info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://doi.org/10.29021/spdv.76.2.804 oai:ojs.revista.spdv.com.pt:article/804 |
url |
https://doi.org/10.29021/spdv.76.2.804 |
identifier_str_mv |
oai:ojs.revista.spdv.com.pt:article/804 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://revista.spdv.com.pt/index.php/spdv/article/view/804 https://doi.org/10.29021/spdv.76.2.804 https://revista.spdv.com.pt/index.php/spdv/article/view/804/569 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Sociedade Portuguesa de Dermatologia e Venereologia |
publisher.none.fl_str_mv |
Sociedade Portuguesa de Dermatologia e Venereologia |
dc.source.none.fl_str_mv |
Journal of the Portuguese Society of Dermatology and Venereology; Vol 76 No 2 (2018): April - June; 185-188 Revista da Sociedade Portuguesa de Dermatologia e Venereologia; v. 76 n. 2 (2018): Abril - Junho; 185-188 2182-2409 2182-2395 reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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