A rare case of malabsorption of thyroid hormones.

Detalhes bibliográficos
Autor(a) principal: Nobre, E Lacerda
Data de Publicação: 2004
Outros Autores: Jorge, Zulmira, Anselmo, J, Lopes, Carlos, César, Rui, Santos, V, Castro, J Jácome de
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1116
Resumo: We describe the case of a 22-year old male undergoing a total thyroidectomy for euthyroid multi-nodular goitre (TSH: 1.6 microUI/ml). He was discharged treated with LT4 100 mg id. After discharge, he went into full clinical and laboratorial hypothyroidism (TSH = 396 microUI/mL). We were able to rule out failure to take the medication and concomitant use of drugs. In the evaluation of intestinal absorption, only the D-Xylose test proved to be abnormal. After unsuccessful administration of oral T4 and T3, under close nursing supervision, intramuscular (IM) and subcutaneous (SC) forms of administration of T4 were experimented. While both forms achieved normal levels of thyroid hormones, we opted for IM injection as the patient complained of local pain during SC administration. This seems to be the second case described in which it was necessary to resort to parenteral administration of T4 to achieve clinical and laboratorial euthyroidism.
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spelling A rare case of malabsorption of thyroid hormones.Má absorção das hormonas tiroideias.We describe the case of a 22-year old male undergoing a total thyroidectomy for euthyroid multi-nodular goitre (TSH: 1.6 microUI/ml). He was discharged treated with LT4 100 mg id. After discharge, he went into full clinical and laboratorial hypothyroidism (TSH = 396 microUI/mL). We were able to rule out failure to take the medication and concomitant use of drugs. In the evaluation of intestinal absorption, only the D-Xylose test proved to be abnormal. After unsuccessful administration of oral T4 and T3, under close nursing supervision, intramuscular (IM) and subcutaneous (SC) forms of administration of T4 were experimented. While both forms achieved normal levels of thyroid hormones, we opted for IM injection as the patient complained of local pain during SC administration. This seems to be the second case described in which it was necessary to resort to parenteral administration of T4 to achieve clinical and laboratorial euthyroidism.We describe the case of a 22-year old male undergoing a total thyroidectomy for euthyroid multi-nodular goitre (TSH: 1.6 microUI/ml). He was discharged treated with LT4 100 mg id. After discharge, he went into full clinical and laboratorial hypothyroidism (TSH = 396 microUI/mL). We were able to rule out failure to take the medication and concomitant use of drugs. In the evaluation of intestinal absorption, only the D-Xylose test proved to be abnormal. After unsuccessful administration of oral T4 and T3, under close nursing supervision, intramuscular (IM) and subcutaneous (SC) forms of administration of T4 were experimented. While both forms achieved normal levels of thyroid hormones, we opted for IM injection as the patient complained of local pain during SC administration. This seems to be the second case described in which it was necessary to resort to parenteral administration of T4 to achieve clinical and laboratorial euthyroidism.Ordem dos Médicos2004-12-31info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1116oai:ojs.www.actamedicaportuguesa.com:article/1116Acta Médica Portuguesa; Vol. 17 No. 6 (2004): November-December; 487-491Acta Médica Portuguesa; Vol. 17 N.º 6 (2004): Novembro-Dezembro; 487-4911646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1116https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1116/781Nobre, E LacerdaJorge, ZulmiraAnselmo, JLopes, CarlosCésar, RuiSantos, VCastro, J Jácome deinfo:eu-repo/semantics/openAccess2022-12-20T10:57:29Zoai:ojs.www.actamedicaportuguesa.com:article/1116Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:16:58.661856Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv A rare case of malabsorption of thyroid hormones.
Má absorção das hormonas tiroideias.
title A rare case of malabsorption of thyroid hormones.
spellingShingle A rare case of malabsorption of thyroid hormones.
Nobre, E Lacerda
title_short A rare case of malabsorption of thyroid hormones.
title_full A rare case of malabsorption of thyroid hormones.
title_fullStr A rare case of malabsorption of thyroid hormones.
title_full_unstemmed A rare case of malabsorption of thyroid hormones.
title_sort A rare case of malabsorption of thyroid hormones.
author Nobre, E Lacerda
author_facet Nobre, E Lacerda
Jorge, Zulmira
Anselmo, J
Lopes, Carlos
César, Rui
Santos, V
Castro, J Jácome de
author_role author
author2 Jorge, Zulmira
Anselmo, J
Lopes, Carlos
César, Rui
Santos, V
Castro, J Jácome de
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Nobre, E Lacerda
Jorge, Zulmira
Anselmo, J
Lopes, Carlos
César, Rui
Santos, V
Castro, J Jácome de
description We describe the case of a 22-year old male undergoing a total thyroidectomy for euthyroid multi-nodular goitre (TSH: 1.6 microUI/ml). He was discharged treated with LT4 100 mg id. After discharge, he went into full clinical and laboratorial hypothyroidism (TSH = 396 microUI/mL). We were able to rule out failure to take the medication and concomitant use of drugs. In the evaluation of intestinal absorption, only the D-Xylose test proved to be abnormal. After unsuccessful administration of oral T4 and T3, under close nursing supervision, intramuscular (IM) and subcutaneous (SC) forms of administration of T4 were experimented. While both forms achieved normal levels of thyroid hormones, we opted for IM injection as the patient complained of local pain during SC administration. This seems to be the second case described in which it was necessary to resort to parenteral administration of T4 to achieve clinical and laboratorial euthyroidism.
publishDate 2004
dc.date.none.fl_str_mv 2004-12-31
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https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1116/781
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dc.publisher.none.fl_str_mv Ordem dos Médicos
publisher.none.fl_str_mv Ordem dos Médicos
dc.source.none.fl_str_mv Acta Médica Portuguesa; Vol. 17 No. 6 (2004): November-December; 487-491
Acta Médica Portuguesa; Vol. 17 N.º 6 (2004): Novembro-Dezembro; 487-491
1646-0758
0870-399X
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