Exploring the phytochemicals of Acacia melanoxylon R. Br.

Detalhes bibliográficos
Autor(a) principal: Alves, Diana
Data de Publicação: 2021
Outros Autores: Duarte, Sidónio, Arsénio, Pedro, Gonçalves, Joana, Rodrigues, Cecíla M.P., Ana Lourenço, Lourenço, Patrícia Máximo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.5/22757
Resumo: Invasive species are currently a world menace to the environment, although the study of their chemistry may provide a means for their future beneficial use. From a study of Portuguese Acacia melanoxylon R. Br. five known compounds were isolated: lupeol, 3 -Z-coumaroyl lupeol, 3 -E-coumaroyl lupeol (dioslupecin A), kolavic acid 15-methyl ester and vomifoliol (blumenol A). Their structures were elucidated by 1D and 2D NMR spectroscopy and mass spectrometry, and as a result some corrections are made to their previous 13C NMR assignments. Cytotoxicity of 3 -Ecoumaroyl lupeol (dioslupecin A) and kolavic acid 15-methyl ester was evaluated against HCT116 human colorectal cancer cells although biological activity was not evident
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spelling Exploring the phytochemicals of Acacia melanoxylon R. Br.invasive speciesAcacia melanoxylonterpenoidsHCT116 human colorectal cancer cellscytotoxicityInvasive species are currently a world menace to the environment, although the study of their chemistry may provide a means for their future beneficial use. From a study of Portuguese Acacia melanoxylon R. Br. five known compounds were isolated: lupeol, 3 -Z-coumaroyl lupeol, 3 -E-coumaroyl lupeol (dioslupecin A), kolavic acid 15-methyl ester and vomifoliol (blumenol A). Their structures were elucidated by 1D and 2D NMR spectroscopy and mass spectrometry, and as a result some corrections are made to their previous 13C NMR assignments. Cytotoxicity of 3 -Ecoumaroyl lupeol (dioslupecin A) and kolavic acid 15-methyl ester was evaluated against HCT116 human colorectal cancer cells although biological activity was not evidentMDPIRepositório da Universidade de LisboaAlves, DianaDuarte, SidónioArsénio, PedroGonçalves, JoanaRodrigues, Cecíla M.P.Ana Lourenço, LourençoPatrícia Máximo2021-12-17T10:30:13Z20212021-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.5/22757engAlves, D.; Duarte, S.; Arsénio, P.; Gonçalves, J.; Rodrigues, C.M.P.; Lourenço, A.; Máximo, P. Exploring the Phytochemicals of Acacia melanoxylon R. Br. Plants 2021https://doi.org/10.3390/ plants10122698info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-03-06T14:52:18Zoai:www.repository.utl.pt:10400.5/22757Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T17:07:06.000191Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Exploring the phytochemicals of Acacia melanoxylon R. Br.
title Exploring the phytochemicals of Acacia melanoxylon R. Br.
spellingShingle Exploring the phytochemicals of Acacia melanoxylon R. Br.
Alves, Diana
invasive species
Acacia melanoxylon
terpenoids
HCT116 human colorectal cancer cells
cytotoxicity
title_short Exploring the phytochemicals of Acacia melanoxylon R. Br.
title_full Exploring the phytochemicals of Acacia melanoxylon R. Br.
title_fullStr Exploring the phytochemicals of Acacia melanoxylon R. Br.
title_full_unstemmed Exploring the phytochemicals of Acacia melanoxylon R. Br.
title_sort Exploring the phytochemicals of Acacia melanoxylon R. Br.
author Alves, Diana
author_facet Alves, Diana
Duarte, Sidónio
Arsénio, Pedro
Gonçalves, Joana
Rodrigues, Cecíla M.P.
Ana Lourenço, Lourenço
Patrícia Máximo
author_role author
author2 Duarte, Sidónio
Arsénio, Pedro
Gonçalves, Joana
Rodrigues, Cecíla M.P.
Ana Lourenço, Lourenço
Patrícia Máximo
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv Alves, Diana
Duarte, Sidónio
Arsénio, Pedro
Gonçalves, Joana
Rodrigues, Cecíla M.P.
Ana Lourenço, Lourenço
Patrícia Máximo
dc.subject.por.fl_str_mv invasive species
Acacia melanoxylon
terpenoids
HCT116 human colorectal cancer cells
cytotoxicity
topic invasive species
Acacia melanoxylon
terpenoids
HCT116 human colorectal cancer cells
cytotoxicity
description Invasive species are currently a world menace to the environment, although the study of their chemistry may provide a means for their future beneficial use. From a study of Portuguese Acacia melanoxylon R. Br. five known compounds were isolated: lupeol, 3 -Z-coumaroyl lupeol, 3 -E-coumaroyl lupeol (dioslupecin A), kolavic acid 15-methyl ester and vomifoliol (blumenol A). Their structures were elucidated by 1D and 2D NMR spectroscopy and mass spectrometry, and as a result some corrections are made to their previous 13C NMR assignments. Cytotoxicity of 3 -Ecoumaroyl lupeol (dioslupecin A) and kolavic acid 15-methyl ester was evaluated against HCT116 human colorectal cancer cells although biological activity was not evident
publishDate 2021
dc.date.none.fl_str_mv 2021-12-17T10:30:13Z
2021
2021-01-01T00:00:00Z
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format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.5/22757
url http://hdl.handle.net/10400.5/22757
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Alves, D.; Duarte, S.; Arsénio, P.; Gonçalves, J.; Rodrigues, C.M.P.; Lourenço, A.; Máximo, P. Exploring the Phytochemicals of Acacia melanoxylon R. Br. Plants 2021
https://doi.org/10.3390/ plants10122698
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