Early social deprivation shapes neuronal programming of the social decision‐making network in a cooperatively breeding fish
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.12/8241 |
Resumo: | The early social environment an animal experiences may have pervasive effects on its behaviour. The social decision-making network (SDMN), consisting of interconnected brain nuclei from the forebrain and midbrain, is involved in the regulation of behaviours during social interactions. In species with advanced sociality such as cooperative breeders, offspring are exposed to a large number and a great diversity of social interactions every day of their early life. This diverse social environment may have life-long consequences on the development of several neurophysiological systems within the SDMN, although these effects are largely unknown. We studied these life-long effects in a cooperatively breeding fish, Neolamprologus pulcher, focusing on the expression of genes involved in the monoaminergic and stress response systems in the SDMN. N. pulcher fry were raised until an age of 2 months either with their parents, subordinate helpers and same-clutch siblings (+F), or with same-clutch siblings only (-F). Analysis of the expression of glucocorticoid receptor, mineralocorticoid receptor, corticotropin releasing factor, dopamine receptors 1 and 2, serotonin transporter and DNA methyltransferase 1 genes showed that early social experiences altered the neurogenomic profile of the preoptic area. Moreover, the dopamine receptor 1 gene was up-regulated in the preoptic area of -F fish compared to +F fish. -F fish also showed up-regulation of GR1 expression in the dorsal medial telencephalon (functional equivalent to the basolateral amygdala), and in the dorsolateral telencephalon (functional equivalent to the hippocampus). Our results suggest that early social environment has life-long effects on the development of several neurophysiological systems within the SDMN. |
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Early social deprivation shapes neuronal programming of the social decision‐making network in a cooperatively breeding fishCooperative breedingDevelopmental plasticityDopamine receptorEarly social experienceGlucocorticoid receptorSocial decision-making networkThe early social environment an animal experiences may have pervasive effects on its behaviour. The social decision-making network (SDMN), consisting of interconnected brain nuclei from the forebrain and midbrain, is involved in the regulation of behaviours during social interactions. In species with advanced sociality such as cooperative breeders, offspring are exposed to a large number and a great diversity of social interactions every day of their early life. This diverse social environment may have life-long consequences on the development of several neurophysiological systems within the SDMN, although these effects are largely unknown. We studied these life-long effects in a cooperatively breeding fish, Neolamprologus pulcher, focusing on the expression of genes involved in the monoaminergic and stress response systems in the SDMN. N. pulcher fry were raised until an age of 2 months either with their parents, subordinate helpers and same-clutch siblings (+F), or with same-clutch siblings only (-F). Analysis of the expression of glucocorticoid receptor, mineralocorticoid receptor, corticotropin releasing factor, dopamine receptors 1 and 2, serotonin transporter and DNA methyltransferase 1 genes showed that early social experiences altered the neurogenomic profile of the preoptic area. Moreover, the dopamine receptor 1 gene was up-regulated in the preoptic area of -F fish compared to +F fish. -F fish also showed up-regulation of GR1 expression in the dorsal medial telencephalon (functional equivalent to the basolateral amygdala), and in the dorsolateral telencephalon (functional equivalent to the hippocampus). Our results suggest that early social environment has life-long effects on the development of several neurophysiological systems within the SDMN.Wiley-Blackwell Publishing LtdRepositório do ISPAAntunes, DiogoTeles, Magda C.Zuellig, MatthewFriesen, Caitlin N.Oliveira, Rui FilipeAubin‐Horth, NadiaTaborsky, Barbara2022-07-01T00:30:15Z2021-01-01T00:00:00Z2021-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.12/8241engAntunes, D., Teles, M..C., Zuellig, M., Friesen, C. N. , Oliveira, R. F., Aubin‐Horth, N. & Taborsky, B.(2021). Earlysocial deprivation shapes neuronal programming of the social decision‐making network in a cooperatively breeding fish. Molecular Ecology Doi: | Revised: 4 June 2021 | Accepted: 11 June 2021 DOI: 10.1111/mec.1601910.1111/mec.16019info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-09-05T16:44:01Zoai:repositorio.ispa.pt:10400.12/8241Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T15:26:04.142494Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Early social deprivation shapes neuronal programming of the social decision‐making network in a cooperatively breeding fish |
title |
Early social deprivation shapes neuronal programming of the social decision‐making network in a cooperatively breeding fish |
spellingShingle |
Early social deprivation shapes neuronal programming of the social decision‐making network in a cooperatively breeding fish Antunes, Diogo Cooperative breeding Developmental plasticity Dopamine receptor Early social experience Glucocorticoid receptor Social decision-making network |
title_short |
Early social deprivation shapes neuronal programming of the social decision‐making network in a cooperatively breeding fish |
title_full |
Early social deprivation shapes neuronal programming of the social decision‐making network in a cooperatively breeding fish |
title_fullStr |
Early social deprivation shapes neuronal programming of the social decision‐making network in a cooperatively breeding fish |
title_full_unstemmed |
Early social deprivation shapes neuronal programming of the social decision‐making network in a cooperatively breeding fish |
title_sort |
Early social deprivation shapes neuronal programming of the social decision‐making network in a cooperatively breeding fish |
author |
Antunes, Diogo |
author_facet |
Antunes, Diogo Teles, Magda C. Zuellig, Matthew Friesen, Caitlin N. Oliveira, Rui Filipe Aubin‐Horth, Nadia Taborsky, Barbara |
author_role |
author |
author2 |
Teles, Magda C. Zuellig, Matthew Friesen, Caitlin N. Oliveira, Rui Filipe Aubin‐Horth, Nadia Taborsky, Barbara |
author2_role |
author author author author author author |
dc.contributor.none.fl_str_mv |
Repositório do ISPA |
dc.contributor.author.fl_str_mv |
Antunes, Diogo Teles, Magda C. Zuellig, Matthew Friesen, Caitlin N. Oliveira, Rui Filipe Aubin‐Horth, Nadia Taborsky, Barbara |
dc.subject.por.fl_str_mv |
Cooperative breeding Developmental plasticity Dopamine receptor Early social experience Glucocorticoid receptor Social decision-making network |
topic |
Cooperative breeding Developmental plasticity Dopamine receptor Early social experience Glucocorticoid receptor Social decision-making network |
description |
The early social environment an animal experiences may have pervasive effects on its behaviour. The social decision-making network (SDMN), consisting of interconnected brain nuclei from the forebrain and midbrain, is involved in the regulation of behaviours during social interactions. In species with advanced sociality such as cooperative breeders, offspring are exposed to a large number and a great diversity of social interactions every day of their early life. This diverse social environment may have life-long consequences on the development of several neurophysiological systems within the SDMN, although these effects are largely unknown. We studied these life-long effects in a cooperatively breeding fish, Neolamprologus pulcher, focusing on the expression of genes involved in the monoaminergic and stress response systems in the SDMN. N. pulcher fry were raised until an age of 2 months either with their parents, subordinate helpers and same-clutch siblings (+F), or with same-clutch siblings only (-F). Analysis of the expression of glucocorticoid receptor, mineralocorticoid receptor, corticotropin releasing factor, dopamine receptors 1 and 2, serotonin transporter and DNA methyltransferase 1 genes showed that early social experiences altered the neurogenomic profile of the preoptic area. Moreover, the dopamine receptor 1 gene was up-regulated in the preoptic area of -F fish compared to +F fish. -F fish also showed up-regulation of GR1 expression in the dorsal medial telencephalon (functional equivalent to the basolateral amygdala), and in the dorsolateral telencephalon (functional equivalent to the hippocampus). Our results suggest that early social environment has life-long effects on the development of several neurophysiological systems within the SDMN. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-01-01T00:00:00Z 2021-01-01T00:00:00Z 2022-07-01T00:30:15Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.12/8241 |
url |
http://hdl.handle.net/10400.12/8241 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Antunes, D., Teles, M..C., Zuellig, M., Friesen, C. N. , Oliveira, R. F., Aubin‐Horth, N. & Taborsky, B.(2021). Earlysocial deprivation shapes neuronal programming of the social decision‐making network in a cooperatively breeding fish. Molecular Ecology Doi: | Revised: 4 June 2021 | Accepted: 11 June 2021 DOI: 10.1111/mec.16019 10.1111/mec.16019 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Wiley-Blackwell Publishing Ltd |
publisher.none.fl_str_mv |
Wiley-Blackwell Publishing Ltd |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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