A3.6 Two components contributing to reduced treg surface CD25 in sle patients and their unaffected relatives

Detalhes bibliográficos
Autor(a) principal: Costa, N
Data de Publicação: 2014
Outros Autores: Marques, O, Godinho, S, Carvalho, C, Leal, B, Vasconcelos, C, Marinho, A, Moraes-Fontes, M F, Gomes da Costa, A, Ponte, C, Marques, R, Coias, T, Martins, A R, Viana, J F, Martins, B, Fesel, C
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.7/677
Resumo: Background FOXP3+ regulatory T-cells (Tregs) in Systemic Lupus Erythematosus (SLE) are in a functionally deficient state with a characteristic reduction or absence of surface CD25 (the IL-2 receptor alpha chain). Genetic variation in the CD25-encoding IL2RA locus is associated with other autoimmune disorders.
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spelling A3.6 Two components contributing to reduced treg surface CD25 in sle patients and their unaffected relativesSystemic Lupus Erythematosus (SLE)CD25FOXP3+Background FOXP3+ regulatory T-cells (Tregs) in Systemic Lupus Erythematosus (SLE) are in a functionally deficient state with a characteristic reduction or absence of surface CD25 (the IL-2 receptor alpha chain). Genetic variation in the CD25-encoding IL2RA locus is associated with other autoimmune disorders.BMJ Publishing GroupARCACosta, NMarques, OGodinho, SCarvalho, CLeal, BVasconcelos, CMarinho, AMoraes-Fontes, M FGomes da Costa, APonte, CMarques, RCoias, TMartins, A RViana, J FMartins, BFesel, C2016-07-08T11:32:13Z2014-032014-03-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.7/677engA3.6 Two components contributing to reduced treg surface CD25 in sle patients and their unaffected relatives N Costa, O Marques, S Godinho, C Carvalho, B Leal, C Vasconcelos, A Marinho, M F Moraes-Fontes, A Gomes da Costa, C Ponte, R Marques, T Coias, A R Martins, J F Viana, B Martins, C Fesel Ann Rheum Dis 2014;73:Suppl 1 A44 doi:10.1136/annrheumdis-2013-205124.10010.1136/annrheumdis-2013-205124.100info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-11-29T14:35:04Zoai:arca.igc.gulbenkian.pt:10400.7/677Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:11:54.830214Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv A3.6 Two components contributing to reduced treg surface CD25 in sle patients and their unaffected relatives
title A3.6 Two components contributing to reduced treg surface CD25 in sle patients and their unaffected relatives
spellingShingle A3.6 Two components contributing to reduced treg surface CD25 in sle patients and their unaffected relatives
Costa, N
Systemic Lupus Erythematosus (SLE)
CD25
FOXP3+
title_short A3.6 Two components contributing to reduced treg surface CD25 in sle patients and their unaffected relatives
title_full A3.6 Two components contributing to reduced treg surface CD25 in sle patients and their unaffected relatives
title_fullStr A3.6 Two components contributing to reduced treg surface CD25 in sle patients and their unaffected relatives
title_full_unstemmed A3.6 Two components contributing to reduced treg surface CD25 in sle patients and their unaffected relatives
title_sort A3.6 Two components contributing to reduced treg surface CD25 in sle patients and their unaffected relatives
author Costa, N
author_facet Costa, N
Marques, O
Godinho, S
Carvalho, C
Leal, B
Vasconcelos, C
Marinho, A
Moraes-Fontes, M F
Gomes da Costa, A
Ponte, C
Marques, R
Coias, T
Martins, A R
Viana, J F
Martins, B
Fesel, C
author_role author
author2 Marques, O
Godinho, S
Carvalho, C
Leal, B
Vasconcelos, C
Marinho, A
Moraes-Fontes, M F
Gomes da Costa, A
Ponte, C
Marques, R
Coias, T
Martins, A R
Viana, J F
Martins, B
Fesel, C
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv ARCA
dc.contributor.author.fl_str_mv Costa, N
Marques, O
Godinho, S
Carvalho, C
Leal, B
Vasconcelos, C
Marinho, A
Moraes-Fontes, M F
Gomes da Costa, A
Ponte, C
Marques, R
Coias, T
Martins, A R
Viana, J F
Martins, B
Fesel, C
dc.subject.por.fl_str_mv Systemic Lupus Erythematosus (SLE)
CD25
FOXP3+
topic Systemic Lupus Erythematosus (SLE)
CD25
FOXP3+
description Background FOXP3+ regulatory T-cells (Tregs) in Systemic Lupus Erythematosus (SLE) are in a functionally deficient state with a characteristic reduction or absence of surface CD25 (the IL-2 receptor alpha chain). Genetic variation in the CD25-encoding IL2RA locus is associated with other autoimmune disorders.
publishDate 2014
dc.date.none.fl_str_mv 2014-03
2014-03-01T00:00:00Z
2016-07-08T11:32:13Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.7/677
url http://hdl.handle.net/10400.7/677
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv A3.6 Two components contributing to reduced treg surface CD25 in sle patients and their unaffected relatives N Costa, O Marques, S Godinho, C Carvalho, B Leal, C Vasconcelos, A Marinho, M F Moraes-Fontes, A Gomes da Costa, C Ponte, R Marques, T Coias, A R Martins, J F Viana, B Martins, C Fesel Ann Rheum Dis 2014;73:Suppl 1 A44 doi:10.1136/annrheumdis-2013-205124.100
10.1136/annrheumdis-2013-205124.100
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv BMJ Publishing Group
publisher.none.fl_str_mv BMJ Publishing Group
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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