Development of L-proline-based Chiral Ionic Liquids for asymmetric Michael Reaction

Detalhes bibliográficos
Autor(a) principal: Zalewska, Karolina
Data de Publicação: 2023
Outros Autores: Pinto, Isabel, Cabrita, Luís, Zakrzewska, Malgorzata E., Noronha, João P., Nunes da Ponte, M., Branco, Luís C.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/152340
Resumo: co-financed by the ERDF under the PT2020 Partnership agreement (POCI-01-0145-FEDER–007265) The NMR spectrometers are part of the National NMR Network (PTNMR) and are partially supported by the Infrastructure Project N◦ 022161 (co-financed by FEDER through COMPETE 2020, POCI and PORL and FCT through PIDDAC).
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spelling Development of L-proline-based Chiral Ionic Liquids for asymmetric Michael Reactionasymmetric Michael reactionchiral ionic liquidsL-prolinesupercritical CO extractionCatalysisEnvironmental Science(all)Physical and Theoretical Chemistryco-financed by the ERDF under the PT2020 Partnership agreement (POCI-01-0145-FEDER–007265) The NMR spectrometers are part of the National NMR Network (PTNMR) and are partially supported by the Infrastructure Project N◦ 022161 (co-financed by FEDER through COMPETE 2020, POCI and PORL and FCT through PIDDAC).Different Chiral Ionic Liquids (CIL) based on L-proline have been developed. Simple and efficient synthetic methodologies are used, allowing preparation in good yields for twelve novel CILs using L-proline as a cation or anion combined with suitable counter-ions. A detailed physical and chemical characterization of the CILs was performed to evaluate the influence of counter-ions on the final properties. The most promissory CILs were tested as efficient chiral catalysts in IL media for asymmetric Michael addition reactions of ketones and aldehydes to nitro-olefins. Similar or even better conversions and enantioselectivities (ee up to 95%) compared to the original L-proline were achieved. Additionally, a good product extraction performance using supercritical CO2 processes was obtained.LAQV@REQUIMTEDQ - Departamento de QuímicaRUNZalewska, KarolinaPinto, IsabelCabrita, LuísZakrzewska, Malgorzata E.Noronha, João P.Nunes da Ponte, M.Branco, Luís C.2023-05-02T22:10:47Z2023-01-252023-01-25T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article16application/pdfhttp://hdl.handle.net/10362/152340eng2073-4344PURE: 51576614https://doi.org/10.3390/catal13020270info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-05-22T18:11:09Zoai:run.unl.pt:10362/152340Portal AgregadorONGhttps://www.rcaap.pt/oai/openairemluisa.alvim@gmail.comopendoar:71602024-05-22T18:11:09Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Development of L-proline-based Chiral Ionic Liquids for asymmetric Michael Reaction
title Development of L-proline-based Chiral Ionic Liquids for asymmetric Michael Reaction
spellingShingle Development of L-proline-based Chiral Ionic Liquids for asymmetric Michael Reaction
Zalewska, Karolina
asymmetric Michael reaction
chiral ionic liquids
L-proline
supercritical CO extraction
Catalysis
Environmental Science(all)
Physical and Theoretical Chemistry
title_short Development of L-proline-based Chiral Ionic Liquids for asymmetric Michael Reaction
title_full Development of L-proline-based Chiral Ionic Liquids for asymmetric Michael Reaction
title_fullStr Development of L-proline-based Chiral Ionic Liquids for asymmetric Michael Reaction
title_full_unstemmed Development of L-proline-based Chiral Ionic Liquids for asymmetric Michael Reaction
title_sort Development of L-proline-based Chiral Ionic Liquids for asymmetric Michael Reaction
author Zalewska, Karolina
author_facet Zalewska, Karolina
Pinto, Isabel
Cabrita, Luís
Zakrzewska, Malgorzata E.
Noronha, João P.
Nunes da Ponte, M.
Branco, Luís C.
author_role author
author2 Pinto, Isabel
Cabrita, Luís
Zakrzewska, Malgorzata E.
Noronha, João P.
Nunes da Ponte, M.
Branco, Luís C.
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv LAQV@REQUIMTE
DQ - Departamento de Química
RUN
dc.contributor.author.fl_str_mv Zalewska, Karolina
Pinto, Isabel
Cabrita, Luís
Zakrzewska, Malgorzata E.
Noronha, João P.
Nunes da Ponte, M.
Branco, Luís C.
dc.subject.por.fl_str_mv asymmetric Michael reaction
chiral ionic liquids
L-proline
supercritical CO extraction
Catalysis
Environmental Science(all)
Physical and Theoretical Chemistry
topic asymmetric Michael reaction
chiral ionic liquids
L-proline
supercritical CO extraction
Catalysis
Environmental Science(all)
Physical and Theoretical Chemistry
description co-financed by the ERDF under the PT2020 Partnership agreement (POCI-01-0145-FEDER–007265) The NMR spectrometers are part of the National NMR Network (PTNMR) and are partially supported by the Infrastructure Project N◦ 022161 (co-financed by FEDER through COMPETE 2020, POCI and PORL and FCT through PIDDAC).
publishDate 2023
dc.date.none.fl_str_mv 2023-05-02T22:10:47Z
2023-01-25
2023-01-25T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/152340
url http://hdl.handle.net/10362/152340
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 2073-4344
PURE: 51576614
https://doi.org/10.3390/catal13020270
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 16
application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv mluisa.alvim@gmail.com
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